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Source: Medicine
Condition: Depression

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Total 62 results found since Jan 2013.

An Increased Risk of Reversible Dementia May Occur After Zolpidem Derivative Use in the Elderly Population: A Population-Based Case-Control Study
Abstract: We evaluate the effects of zolpidem use to develop dementia or Alzheimer disease from the Taiwan National Health Insurance Research Database (NHIRD). A retrospective population-based nested case–control study. Newly diagnosed dementia patients 65 years and older and controls were sampled. A total of 8406 dementia and 16,812 control subjects were enrolled from Taiwan NHIRD during 2006 to 2010. The relationships between zolpidem use and dementia were measured using odds and adjusted odds ratios. The relationship between the average cumulative doses for zolpidem and dementia was also analyzed. Zolpidem alone or wi...
Source: Medicine - May 1, 2015 Category: Internal Medicine Tags: Article: Observational Study Source Type: research

Low Serum Levels of Uric Acid are Associated With Development of Poststroke Depression
This study sought to examine the possible association between serum uric acid levels and the development of PSD. We recruited 196 patients with acute ischemic stroke and 100 healthy volunteers. Serum uric acid levels were tested by uricase-PAP method within 24 hr after admission. Neuropsychological evaluations were conducted at 3-month poststroke. The 17-item Hamilton Depression Scale was used to assess depressive symptoms. Diagnosis of PSD was made in accordance with DSM-IV criteria for depression. Multivariate analyses were conducted using logistic regression models. Fifty-six patients (28.6%) were diagnosed as having ...
Source: Medicine - November 1, 2015 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Edaravone reduces depression severity in patients with symptomatic intracranial stenosis and is associated with the serum expression of sex hormones
Objective: To investigate the effect of edaravone on depression relief in symptomatic patients with intracranial stenosis and its relationship with the expression of sex hormones. Methods: We recruited 112 patients with symptomatic intracranial arterial stenosis from Renmin Hospital, Wuhan University, between October 2014 and October 2017. All patients were divided into the traditional or experimental (traditional treatment + intravenous infusion of edaravone 30 mg twice a day for 14 days) treatment groups. The general clinical data were collected, and neurological functional recovery using the Modified Rankin Scale...
Source: Medicine - February 1, 2020 Category: Internal Medicine Tags: Research Article: Clinical Trial/Experimental Study Source Type: research

Complementary and alternative therapies for poststroke depression: A protocol for systematic review and network meta-analysis
Conclusion: The results of this study will provide references for evaluating the effects of different CAM therapies on PSD, and provide decision-making references for clinical practitioners, patients, and health policy makers. Ethics and dissemination: This study does not require ethical approval. the results will be disseminated through a peer-reviewed publication. OSF registration number: DOI 10.17605/OSF.IO/TNGH6.
Source: Medicine - September 18, 2020 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research

Efficacy and safety of massage in the treatment of poststroke depression: A systematic review and meta-analysis of protocols
Conclusion: It will be substantiated in this review whether massage therapy is a reliable intervention for poststroke depression by examining the evidence collected. INPLASY registration number: INPLASY2020110085.
Source: Medicine - January 29, 2021 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research

Association Between Tuberculosis and Parkinson Disease: A Nationwide, Population-Based Cohort Study
Abstract: Few studies have investigated the association between tuberculosis (TB) and Parkinson disease (PD). This nationwide, population-based, retrospective cohort study investigated the risk of PD in patients with TB. We selected patients newly diagnosed with TB (International Classification of Diseases, Ninth Revision, Clinical Modification: 011) from 2000 to 2009 in the Taiwan National Health Insurance Database as the TB cohort. The comparison cohort (the non-TB cohort) was frequency matched to the TB cohort at a ratio of 4:1 by sex, age, and the index date. We analyzed the risks of PD by using Cox proportional hazar...
Source: Medicine - February 1, 2016 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Profile of the Older Population Living in Miami-Dade County, Florida: An Observational Study
This study examined cross-sectional data (demographics, health outcomes, risk factors, health assess, and utilization) collected from probability-sampled, household-based surveys conducted in 3 areas of MDC: north Miami-Dade, Little Haiti, and South Miami. The questionnaire was administered face-to-face by trained interviewers in English, Spanish, French, or Creole. Analyses were restricted to households containing at least 1 member aged 65 years or older (n = 935). One consenting adult answered the questionnaire on behalf of household members. The mean age of the respondent (60% females) was 60 years. Overall, respon...
Source: Medicine - May 1, 2016 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Pharmacological and psychotherapeutic interventions for management of poststroke depression: A Bayesian network meta-analysis of randomized controlled trials
Conclusion: Formal ethical approval is not required as primary data will not be collected. Our results will help to reduce the uncertainty about the effectiveness and safety of PSD management, which will encourage further research for other therapeutic options. The review will be disseminated in peer-reviewed publications and conference presentations. PROSPERO registration number: CRD42016049049
Source: Medicine - February 1, 2017 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research

Effectiveness of paroxetine in the treatment of poststroke depression
This study retrospectively investigated the effectiveness of paroxetine for the treatment of poststroke depression (PSD). Seventy patient cases with PSD were included in this study, and were assigned to an intervention group and a control group equally. All patients received routine treatment in both groups. Additionally, patients in the intervention group underwent paroxetine, while patients in the control group received psychotherapy for a total of 8 weeks intervention. The primary outcomes included depression, measured by Hamilton depression rating scale (HAMD); and anxiety, measured by Hamilton Anxiety Rating Scale (H...
Source: Medicine - July 1, 2018 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Sensory-motor and cardiorespiratory sensory rehabilitation associated with transcranial photobiomodulation in patients with central nervous system injury: Trial protocol for a single-center, randomized, double-blind, and controlled clinical trial
Background: Central nervous system diseases such as stroke, spinal cord injury, traumatic brain injury, and multiple sclerosis can be fatal or cause sequelae, affecting sensorimotor and cardiorespiratory systems and quality of life. These subjects present a low response to aerobic and resistance exercise, due to decreased recruitment of muscle fibers and reduction of metabolic capacity. Aerobic exercises bring benefits in terms of fatigue retardation, gait improvement, regulation of the autonomic nervous system, neuroprotection of the brain, stimulation of the production of endogenous neutrotransmitters related to genera...
Source: Medicine - June 1, 2019 Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research

Comparative effectiveness of different forms of traditional Chinese medicine for treatment of post-stroke depression: Protocol for network meta-analysis of randomized controlled trials: Erratum
No abstract available
Source: Medicine - October 1, 2019 Category: Internal Medicine Tags: Erratum Source Type: research

Network meta-analysis of Chinese patent medicine adjuvant treatment of poststroke depression
Conclusion: This study will provide systematic evidence-based medicine evidence for Chinese patent medicine adjuvant treatment for poststroke depression, and help clinicians, patients with poststroke depression and decision-makers to make more effective, safer, and economic optimal treatment plan in the decision-making process. PROSPERO registration number: CRD42020164543
Source: Medicine - July 31, 2020 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research

Association between periodontitis and bipolar disorder: A nationwide cohort study
Whether periodontitis is a risk factor for developing bipolar disorders (BD) has not been investigated. We aimed to determine whether periodontitis is associated with the subsequent development of BD and examine the risk factors for BD among patients with periodontitis. Using ambulatory and inpatient claims data from the National Health Insurance Research Database (NHIRD), we identified 12,337 patients who were aged at least 20 years and newly diagnosed with periodontitis between 2000 and 2004. The date of the first claim with a periodontitis diagnosis was set as the index date. For each patient with periodontitis, 4 subj...
Source: Medicine - July 31, 2020 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Nonpharmacological therapies for central poststroke pain: A systematic review
Conclusions: Nonpharmacological therapies appear to be effective in CPSP, but the evidence is relatively weak. Invasive electrical brain stimulation can be accompanied by serious adverse events, but most patients recover from these effects.
Source: Medicine - October 16, 2020 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

Efficacy of individualized education in patients with type 2 diabetes mellitus: A randomized clinical study protocol
Conclusion: Individualized diabetes education may improve the clinical outcomes in patients with type 2 DM. Trial registration: The protocol was registered in Research Registry (researchregistry6232).
Source: Medicine - December 11, 2020 Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research