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Source: Biochimica et Biophysica Acta (BBA) Molecular Cell Research
Condition: Depression

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HPI/AMF inhibition halts the development of the aggressive phenotype of breast cancer stem cells
Publication date: Available online 23 June 2017 Source:Biochimica et Biophysica Acta (BBA) - Molecular Cell Research Author(s): Juan Carlos Gallardo-Pérez, Alhelí Adán-Ladrón de Guevara, Alvaro Marín-Hernández, Rafael Moreno-Sánchez, Sara Rodríguez-Enríquez Cancer stem cells are responsible for tumor recurrence and metastasis. A new highly reproducible procedure for human breast cancer MCF-7 stem cells (BCSC) isolation and selection was developed by using a combination of hypoxia/hypoglycemia plus taxol and adriamycin for 24h. The BCSC enriched fraction (i) expressed (2–15 times) the typical stemness protein ma...
Source: Biochimica et Biophysica Acta (BBA) Molecular Cell Research - June 23, 2017 Category: Molecular Biology Source Type: research