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Molecular Mechanisms of Lipid-Based Metabolic Adaptation Strategies in Response to Cold
Cells. 2023 May 10;12(10):1353. doi: 10.3390/cells12101353.ABSTRACTTemperature changes and periods of detrimental cold occur frequently for many organisms in their natural habitats. Homeothermic animals have evolved metabolic adaptation strategies to increase mitochondrial-based energy expenditure and heat production, largely relying on fat as a fuel source. Alternatively, certain species are able to repress their metabolism during cold periods and enter a state of decreased physiological activity known as torpor. By contrast, poikilotherms, which are unable to maintain their internal temperature, predominantly increase me...
Source: Cancer Control - July 6, 2023 Category: Cancer & Oncology Authors: Gang Wu Ralf Baumeister Thomas Heimbucher Source Type: research