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Source: Advances in Chronic Kidney Disease
Condition: Nephritis
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The Impact of APOL1 on Chronic Kidney Disease and Hypertension
This article reviews relationships between mild to moderate essential hypertension and chronic kidney disease with a focus on the role of APOL1 in development of hypertension. Available evidence strongly supports that APOL1 renal-risk variants associate with glomerulosclerosis in African Americans, which then causes secondary hypertension, not with essential hypertension per se.
Source: Advances in Chronic Kidney Disease - April 24, 2019 Category: Urology & Nephrology Source Type: research
