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Cost-Effectiveness of Statins for Primary Cardiovascular Prevention in Chronic Kidney Disease
ConclusionsAlthough statins reduce absolute CVD risk in patients with CKD, the increased risk of rhabdomyolysis, and competing risks associated with progressive CKD, partly offset these gains. Low-cost generic statins appear cost-effective for primary prevention of CVD in patients with mild-to-moderate CKD and hypertension.
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - March 18, 2013 Category: Cardiology Source Type: research

Soluble Guanylate Cyclase Stimulators: a Novel Treatment Option for Heart Failure Associated with Cardiorenal Syndromes?
Abstract Heart failure in the setting of chronic kidney disease (CKD) is an increasingly common scenario and carries a poor prognosis. Clinicians lack tools for primary or secondary heart failure prevention in patients with cardiorenal syndromes. In patients without CKD, angiotensin-converting enzyme inhibitors (ACE-I) or angiotensin receptor blockers (ARB) and statins mitigate cardiovascular risk in large part due to salutary effects on the endothelium. In the setting of CKD, use of these therapies is limited by adverse effects of hyperkalemia in pre-dialysis CKD (ACE-I/ARB), or potential increased risk of stroke...
Source: Current Heart Failure Reports - April 26, 2016 Category: Cardiology Source Type: research

Low Body Mass Index without Malnutrition Is an Independent Risk Factor for Major Cardiovascular Events in Patients with Hemodialysis
In conclusion, BMI < 18.5 without malnutrition may be an independent risk factor for MACE in patients with hemodialysis.PMID:36184553 | DOI:10.1536/ihj.22-333
Source: International Heart Journal - October 2, 2022 Category: Cardiology Authors: Takuya Kishi Akira Kitajima Kohei Yamanouchi Yoshitaka Hirooka Shuji Toda Ayako Takamori Kazuma Fujimoto Chie Kishi Yoshiyuki Tomiyoshi Source Type: research

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