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IJERPH, Vol. 15, Pages 2733: Statins and Cardiovascular Disease Outcomes in Chronic Kidney Disease: Reaffirmation vs. Repudiation
orris Cardiovascular disease (CVD) burden is several-fold higher in patients with chronic kidney disease (CKD). Although statins have been shown to provide significant CVD benefits in both the general population and patients with CKD, this has not translated into survival advantage in patients with advanced CKD or on dialysis. It has been reported that CVD risk continues to escalate as CKD progresses to end-stage kidney disease (ESKD); however, the CVD risk reduction by statins appears to decline as patients’ progress from the early to later stages of CKD. Statins have also been associated with a higher i...
Source: International Journal of Environmental Research and Public Health - December 4, 2018 Category: Environmental Health Authors: Chamberlain I. Obialo Elizabeth O. Ofili Keith C. Norris Tags: Review Source Type: research