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Combined Application of Human Amniotic Membrane Mesenchymal Stem Cells and a Modified PGS-co-PCL Film in an Experimental Model of Myocardial Ischemia-Reperfusion Injury
Appl Biochem Biotechnol. 2023 Apr 3. doi: 10.1007/s12010-023-04446-5. Online ahead of print.ABSTRACTAccording to the World Health Organization (WHO), about 3.9 million people die annually of ischemic heart disease (IHD). Several clinical trials have shown that stem cell therapy is a promising therapeutic approach to IHD. Human amniotic membrane mesenchymal stem cells (hAMSCs) positively affect the repair of myocardial ischemia-reperfusion (MI/R) injury by stimulating endogenous repair mechanisms. The differentiated hAMSCs with and without modified PGS-co-PCL film were applied in the myocardium. MI/R injury was induced by l...
Source: Applied Biochemistry and Biotechnology - April 3, 2023 Category: Biochemistry Authors: Nastaran Bahrami Mahsa Ale-Ebrahim Yasin Asadi Nooshin Barikrow Ali Salimi Fatemeh Roholah Source Type: research

Nanodomains in cardiopulmonary disorders and the impact of air pollution.
Abstract Air pollution is a major environmental threat and each year about 7 million people reported to die as a result of air pollution. Consequently, exposure to air pollution is linked to increased morbidity and mortality world-wide. Diesel automotive engines are a major source of urban air pollution in the western societies encompassing particulate matter and diesel exhaust particles (DEP). Air pollution is envisioned as primary cause for cardiovascular dysfunction, such as ischemic heart disease, cardiac dysrhythmias, heart failure, cerebrovascular disease and stroke. Air pollution also causes lung dysfunctio...
Source: Biochemical Society Transactions - June 28, 2020 Category: Biochemistry Authors: Cattani-Cavalieri I, Valença SDS, Schmidt M Tags: Biochem Soc Trans Source Type: research