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Thrombosis in Fontan patient on apixaban
We report a case of large thrombus in a 24-year-old male born with double inlet left ventricle in the lateral tunnel Fontan while on apixaban.
Source: International Journal of Cardiology - December 27, 2014 Category: Cardiology Authors: Candida Pinto, Bennett P. Samuel, Christopher Ratnasamy, Joseph J. Vettukattil Source Type: research

Cost-Effectiveness Analysis of Alternative Screening and Treatment Strategies for Heterozygous Familial Hypercholesterolemia in the United States
This study evaluates the cost-effectiveness of genetic screening and lipid-based screening with statin adherence measures compared to lipid-based screening alone in the US.
Source: International Journal of Cardiology - December 23, 2014 Category: Cardiology Authors: Christina X. Chen, Joel W. Hay Source Type: research

Risk of cardiovascular disease: The effects of diabetes and anti-diabetic drugs — A nested case–control study
Type 2 diabetes (DM) increases the risk of cardiovascular disease. We investigated the effects of antidiabetic drugs on the composite endpoint (CE) of ischemic heart disease, heart failure or stroke in DM patients.
Source: International Journal of Cardiology - November 13, 2014 Category: Cardiology Authors: Michael Gejl, Jakob Starup-Linde, Jan Scheel-Thomsen, Soeren Gregersen, Peter Vestergaard Source Type: research

Risk of cardiovascular disease: The effects of diabetes and anti-diabetic drugs - a nested case-control study
Type 2 diabetes (DM) increases the risk of cardiovascular disease. We investigated the effects of antidiabetic drugs on the composite endpoint (CE) of ischemic heart disease, heart failure or stroke in DM patients.
Source: International Journal of Cardiology - November 13, 2014 Category: Cardiology Authors: Michael Gejl, Jakob Starup-Linde, Jan Scheel-Thomsen, Soeren Gregersen, Peter Vestergaard Source Type: research

Patterns of cardiovascular drugs prescribed for an elderly Swedish population
Cardiovascular diseases (CVDs), such as coronary heart disease, atrial fibrillation, heart failure and stroke, are increasingly common as people age. Therefore, cardiovascular drugs are the most frequently prescribed medications for preventive and therapeutic purposes among older adults [1]. However, several factors make cardiovascular drug treatment in elderly people complicated. Age-related pathophysiological changes in the cardiovascular system, liver and kidney can affect the pharmacokinetics and pharmacodynamics of commonly used drugs, which makes older persons more vulnerable to adverse drug events [2].
Source: International Journal of Cardiology - October 7, 2014 Category: Cardiology Authors: Mozhu Ding, Rui Wang, Kristina Johnell, Chengxuan Qiu Tags: Letter to the Editor Source Type: research

A Brugada-like electrocardiogram pattern induced after radiofrequency catheter ablation of atrial fibrillation
Radiofrequency catheter ablation (RFCA) of the left atrium (LA) targeting the initiating triggers inside the pulmonary vein (PV) to disconnect PVs has become a very promising and successful treatment in patients with symptomatic and drug refractory atrial fibrillation (AF) of no or minimal structural heart disease [1]. Known complications of RFCA have been defined and investigated, including pulmonary vein stenosis, aortic root and atrial perforation, stroke and pericardial effusion and so on [1,2].
Source: International Journal of Cardiology - August 23, 2014 Category: Cardiology Authors: Chunying Jiang, Rui Wang, Wen Lu, Bing Han Tags: Letter to the Editor Source Type: research

Edentulism associates with poor cardiovascular health. Results from the Atahualpa Project
Edentulism – used as a proxy for chronic inflammatory periodontal disease – has been linked to an increased risk of adverse vascular outcomes [1]. While the importance of this relationship has been studied in industrialized nations, there is scarce information on its public health impact in underserved populations. Limited access to oral health care and lack of awareness on the repercussions of poor dental habits on systemic health contribute to the problem, and may be one of the factors responsible for the increasing burden of stroke and ischemic heart disease in rural areas of Latin America [2].
Source: International Journal of Cardiology - August 1, 2014 Category: Cardiology Authors: Oscar H. Del Brutto, Robertino M. Mera, Victor J. Del Brutto, Mauricio Zambrano, Jipson E. Montenegro, Pablo R. Castillo Tags: Letter to the Editor Source Type: research

Edentulism associates with poor cardiovascular health. Results from The Atahualpa Project
Edentulism – used as a proxy for chronic inflammatory periodontal disease – has been linked to an increased risk of adverse vascular outcomes [1]. While the importance of this relationship has been studied in industrialized nations, there is scarce information on its public health impact in underserved populations. Limited access to oral health care and lack of awareness on the repercussions of poor dental habits on systemic health contributes to the problem, and may be one of the factors responsible for the increasing burden of stroke and ischemic heart disease in rural areas of Latin America [2].
Source: International Journal of Cardiology - August 1, 2014 Category: Cardiology Authors: Oscar H. Del Brutto, Robertino M. Mera, Victor J. Del Brutto, Mauricio Zambrano, Jipson E. Montenegro, Pablo R. Castillo Source Type: research

Adherence to dietary guidelines and cardiovascular disease risk in the EPIC-NL cohort
Global and national dietary guidelines have been created to lower chronic disease risk. The aim of this study was to assess whether greater adherence to the WHO guidelines (Healthy Diet Indicator (HDI)); the Dutch guidelines for a healthy diet (Dutch Healthy Diet-index (DHD-index)); and the Dietary Approaches to Stop Hypertension (DASH) diet was associated with a lower risk of cardiovascular disease (CVD), coronary heart disease (CHD) or stroke.
Source: International Journal of Cardiology - July 12, 2014 Category: Cardiology Authors: Ellen A. Struijk, Anne M. May, Nick L.W. Wezenbeek, Heidi P. Fransen, Sabita S. Soedamah-Muthu, Anouk Geelen, Jolanda M.A. Boer, Yvonne T. van der Schouw, H. Bas Bueno-de-Mesquita, Joline W.J. Beulens Source Type: research

Risk of coronary heart disease and risk of stroke in women with polycystic ovary syndrome: A systematic review and meta-analysis
Source: International Journal of Cardiology - July 8, 2014 Category: Cardiology Authors: Sarah Anderson, John A. Barry, Paul J. Hardiman Source Type: research

Secular changes in rates of coronary heart disease, fatal coronary heart disease, and out-of-hospital fatal coronary heart disease
In the Atherosclerosis Risk in Communities (ARIC) surveillance study, out-of-hospital fatal coronary heart disease (CHD) declined more slowly than total fatal CHD over 1987–2008 ; however, the upper age limit was 74 and temporal changes in risk factors and preventive therapies were not considered. To evaluate secular trends in CHD, fatal CHD, and out-of-hospital fatal CHD in a broader age range accounting for changes in risk factors and therapies, we used data from the ARIC cohort study , the Cardiovascular Health Study (CHS) , and the REasons for Geographic And Racial Differences in Stroke (REGARDS) study . ARIC and CHS...
Source: International Journal of Cardiology - April 24, 2014 Category: Cardiology Authors: Emily B. Levitan, Rikki M. Tanner, Hong Zhao, Paul Muntner, Evan L. Thacker, George Howard, Stephen P. Glasser, Vera Bittner, Michael E. Farkouh, Robert S. Rosenson, Monika M. Safford Tags: Letters to the Editor Source Type: research

The relationship between insulin-sensitive obesity and cardiovascular diseases in a Chinese population: Results of the REACTION study
Conclusion: Both general and abdominal obesity were associated with elevated prevalent cardiovascular diseases and 10-year CHD risk, regardless of the presence or absence of insulin resistance.
Source: International Journal of Cardiology - February 6, 2014 Category: Cardiology Authors: Jieli Lu, Yufang Bi, Tiange Wang, Weiqing Wang, Yiming Mu, Jiajun Zhao, Chao Liu, Lulu Chen, Lixin Shi, Qiang Li, Qin Wan, Shengli Wu, Guijun Qin, Tao Yang, Li Yan, Yan Liu, Guixia Wang, Zuojie Luo, Xulei Tang, Gang Chen, Yanan Huo, Zhengnan Gao, Qing Su, Tags: Original Articles Source Type: research

Successful management of a twice complicated case by implantation of three CoreValve prostheses
An 80year old man, diabetic on oral medication and with permanent atrial fibrillation with a single chamber pacemaker, was referred to our hospital for severe symptomatic aortic valve stenosis. His trans-thoracic echocardiography confirmed severe aortic stenosis with a mean/peak gradient of 45/85mmHg, an estimated aortic valve area of 0.7cm2 and good systolic function with an ejection fraction of 50%. His past medical history was remarkable for a minor stroke without neurological impairment and moderate kidney dysfunction with creatinine of 2.3mg/dL. A cardiac catheterization revealed no obstructive coronary heart disease.
Source: International Journal of Cardiology - January 27, 2014 Category: Cardiology Authors: George Latsios, Kostantinos Toutouzas, Dimitris Tousoulis, Andreas Synetos, Antonios Mastrokostopoulos, Konstantinos Stathogiannis, Themis Spyridopoulos, Ulrich Gerckens, Christodoulos Stefanadis Tags: Letters to the Editor Source Type: research

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