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Sex and gender differences in risk, pathophysiology and complications of type 2 diabetes mellitus.
Authors: Kautzky-Willer A, Harreiter J, Pacini G Abstract T2DM is more frequently diagnosed at lower age and body-mass-index in men, however the most prominent risk factor, which is obesity, is more common in women. Generally, large sex-ratio differences across countries are observed. Diversities in biology, culture, lifestyle, environment and socioeconomic status impact differences between males and females in predisposition, development and clinical presentation. Genetic effects and epigenetic mechanisms, nutritional factors and sedentary lifestyle affect risk and complications differently in both sexes. Furtherm...
Source: Endocrine Reviews - May 11, 2016 Category: Endocrinology Tags: Endocr Rev Source Type: research