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Source: Annals of Allergy, Asthma and Immunology
Condition: Hives
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Total 345 results found since Jan 2013.
Generalized urticaria following the use of e-cigarette: a case reported during a switching trial
E-cigarettes (ECs) are popular, yet controversial, tobacco-cigarette substitutes among smokers worldwide1 and are typically used by US youth.2
Source: Annals of Allergy, Asthma and Immunology - September 5, 2023 Category: Allergy & Immunology Authors: Stefan Gospodaru, Gheorghe Bordeniuc, Valeriu Fala, Thomas Bruce Casale, Riccardo Polosa Tags: Letters Source Type: research
Recall Urticaria with Infusion of Agalsidase Beta
No funding was received for this work.
Source: Annals of Allergy, Asthma and Immunology - August 7, 2023 Category: Allergy & Immunology Authors: Raagini Suresh Yedidi, Jonathan A. Bernstein Tags: Letters Source Type: research
Evidence-based use of antihistamines for treatment of allergic conditions
Available since the 1940s, H1-antihistamines are mainstay treatments for allergic conditions such as allergic rhinitis and urticaria. They function as inverse agonists that bind to the H1 receptor to inhibit histamine-induced inflammation. The older, first-generation drugs are no longer recommended for patient use due to their well documented negative side effect profile. Evidence has been accumulating to support a newer generation of H1-antihistamines in oral and intranasal formulations, including in combination with intranasal corticosteroids.
Source: Annals of Allergy, Asthma and Immunology - July 28, 2023 Category: Allergy & Immunology Authors: Sophia Linton, Lubnaa Hossenbaccus, Anne K. Ellis Tags: CME Reviews Source Type: research
Zymogen Granule Protein 16-like and Carboxypeptidase B, new allergens in Hedgehog hypersensitivity
Pet ownership is becoming more and more common.1 Even most exotic ones such as hedgehog, seem to be getting fashionable. However they are not exempt from causing allergies. Hedgehogs are spiny mammals that belong to the subfamily Erinaceinae, order Erinaceomorpha. They are originally from Europe, Asia and Africa. There are 6 genera and 15 species of hedgehogs. Among these, the one most frequently encountered in captivity is the african pygmy hedgehog. Pygmy Hedgehog has been reported to prompt different symptoms ranging from nasal itching to urticaria or even respiratory problems.
Source: Annals of Allergy, Asthma and Immunology - May 27, 2023 Category: Allergy & Immunology Authors: Isabel El ías-Sáenz, Natalia Rodríguez-Otero, Carlos Fernández-Lozano, Borja Bartolomé-Zavala, David González-de-Olano Source Type: research
Safety and outcomes of “at-home self-provocation tests” in patients with mild nonsteroidal anti-inflammatory drug–induced urticaria/angioedema
Nonsteroidal anti-inflammatory drug (NSAID) hypersensitivity is common; however, many patients do not receive an accurate diagnosis and are using unnecessary alternative drugs or have medication restrictions.
Source: Annals of Allergy, Asthma and Immunology - April 23, 2023 Category: Allergy & Immunology Authors: So-Young Park, Youngsang Yoo, Jin-Young Huh, Daegeun Lee, Kangjoon Kim, Jae-Woo Jung, Jae-Chol Choi, Ji-Hyang Lee, Woo-Jung Song, Tae-Bum Kim, You-Sook Cho, Hyouk-Soo Kwon Source Type: research
Safety and outcomes of “at-home self-provocation tests” in patients with mild NSAID-induced urticaria/angioedema (NIUA)
Drug hypersensitivity reactions (DHRs) are unpredictable and heterogeneous type B adverse drug reactions (ADRs).1,2 Various drugs can lead to hypersensitivity; however, nonsteroidal anti-inflammatory drugs (NSAIDs) are recognized as one of the most common causes.3,4 Although NSAID hypersensitivity varies in symptoms, time of onset, and involved mechanisms, it can be categorized according to two major mechanisms: (1) non-immunological mechanisms, such as pharmacologic (secondary to cyclooxygenase-1 (COX-1) inhibition); or (2) immune-mediated reactions (specific IgE or T cells).
Source: Annals of Allergy, Asthma and Immunology - April 23, 2023 Category: Allergy & Immunology Authors: So-Young Park, Young-Sang Yoo, Jin-Young Huh, Daegeun Lee, Jae-Woo Jung, Ji-Hyang Lee, Woo-Jung Song, Tae-Bum Kim, You-Sook Cho, Hyouk-Soo Kwon Tags: Original Article Source Type: research
Severe atopic dermatitis improved with identification and targeted therapy of cholinergic urticaria
Abbreviations: AD = atopic dermatitis; QoL = quality of life
Source: Annals of Allergy, Asthma and Immunology - February 7, 2023 Category: Allergy & Immunology Authors: Ashley Y. Wu, Jessica H. Plager, Basil M. Kahwash Source Type: research
A confirmed fosfomycin induced mast cell activation with anaphylaxis
We present the case of a 61-year-old woman who was prescribed fosfomycin-tromethamine (Monuril ®) because of an uncomplicated urinary tract infection. She had no known previous exposure to fosfomycin-tromethamine. Within 10 minutes after intake of a first single oral dose of 3g, the patient experienced anaphylaxis with generalized pruritus, hives on the extremities, nausea, diarrhea, and sev ere hypotension (blood pressure 60/30 mmHg). She recovered after two intramuscular injections of epinephrine 0.5 mg.
Source: Annals of Allergy, Asthma and Immunology - December 12, 2022 Category: Allergy & Immunology Authors: Michiel Beyens, Dorien Pint, Alessandro Toscano, Didier Ebo, Vito Sabato Tags: Letters Source Type: research
A confirmed fosfomycin-induced mast cell activation with anaphylaxis
We present the case of a 61-year-old woman who was prescribed fosfomycin-tromethamine (Monuril, Zambon, Brussel, Belgium) because of an uncomplicated urinary tract infection. She had no known previous exposure to fosfomycin-tromethamine. Within 10 minutes after intake of a first single oral dose of 3 g, the patient experienced anaphylaxis with generalized pruritus, hives on the extremities, nausea, diarrhea, and severe hypotension (blood pressure 60/30 mm Hg). She recovered after 2 intramuscular injections of epinephrine 0.5 mg.
Source: Annals of Allergy, Asthma and Immunology - December 12, 2022 Category: Allergy & Immunology Authors: Michiel Beyens, Dorien Pint, Alessandro Toscano, Didier Ebo, Vito Sabato Tags: Letters Source Type: research
Update on skin diseases
Recent articles on allergic skin conditions indicate ongoing progress in the understanding of these conditions and advances in management strategies. These articles include studies with very practical and immediate application to the clinical management of patients, in addition to data on emerging therapeutic options. Starting with urticaria, De et al1 conducted a study to evaluate the readability, quality, and timeliness of online patient educational content for urticaria. Of 35 websites analyzed, none scored “excellent,” and only 5 scored “good” using validated quality assessment instruments.
Source: Annals of Allergy, Asthma and Immunology - November 30, 2022 Category: Allergy & Immunology Authors: Marc A. Riedl Tags: Editorial Source Type: research
Interleukin-6 and cytokine release syndrome
Immediate drug hypersensitivity reactions (DHRs) are historically thought to be because of immunoglobulin E (IgE) cross-linking, causing mast cell degranulation and release of mediators like tryptase and histamine. With the increasing use of monoclonal antibodies, it has become apparent that some patients present atypical features during immediate DHRs, including occurrence in initial exposure, a lack of urticaria and angioedema, and the presence of fever, chills, rigors and musculoskeletal pain as the predominant symptoms.
Source: Annals of Allergy, Asthma and Immunology - November 4, 2022 Category: Allergy & Immunology Authors: Erika Yue Lee, Baruch D. Jakubovic Tags: Review Source Type: research
IL-6 and Cytokine Release Syndrome: a new understanding in drug hypersensitivity reactions
Immediate drug hypersensitivity reactions (DHRs) are historically thought to be due to IgE cross-linking, causing mast cell degranulation and release of mediators like tryptase and histamine. With the increasing use of monoclonal antibodies, it has become apparent that some patients present atypical features during immediate DHRs, including occurrence in initial exposure, a lack of urticaria and angioedema, and presence of fever, chills rigors and musculoskeletal pain as the predominant symptoms.
Source: Annals of Allergy, Asthma and Immunology - November 4, 2022 Category: Allergy & Immunology Authors: Erika Yue Lee, Baruch D Jakubovic Tags: Review Source Type: research
Swelling without hives and normal complement
Patients presenting with isolated angioedema without urticaria or wheals, who have normal complement study results, are a clinical challenge. Assuming the clinician has ruled out drug-induced (eg, ace inhibitor [ACE-i] mediated) angioedema, these patients can be difficult to manage. This in part is owing to lack of diagnostic testing available to the clinician to determine a true pathophysiology (is it kinin mediated, histamine mediated, or other?). Depending on the literature you read, these patients can be classified as having normal C1 inhibitor hereditary angioedema (HAE) if there is a family history or genetic testing...
Source: Annals of Allergy, Asthma and Immunology - November 1, 2022 Category: Allergy & Immunology Authors: Jay Adam Lieberman Tags: Editorial Source Type: research
Persistently elevated baseline tryptase - a case of hereditary alpha tryptasemia
Hereditary Alpha Tryptasemia (HaT) is an autosomal dominant genetic condition resulting from inheriting an extra TPSAB1 gene copy, which encodes alpha and beta tryptase. Most cases involve increased copy numbers of alpha tryptase gene, but documented cases of beta tryptase gene duplications exist. HaT typically presents with tryptase levels greater than 8 ng/mL. Phenotypes vary in severity and history may include idiopathic anaphylaxis, vibratory urticaria, musculoskeletal problems, and dysautonomia.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2022 Category: Allergy & Immunology Authors: A. Khan Tags: M367 Source Type: research
Chronic spontaneous urticaria, low histamine diet as a treatment
Chronic Spontaneous Urticaria (CSU) is defined as urticaria that persists longer than six weeks. It was previously known as Chronic Idiopathic Urticaria. The current mainstay treatments for CSU include antihistamines and immunomodulators. The exact pathogenesis of CSU remains unclear. Here, we discuss two patients treated for CSU who demonstrated persistently elevated histamine levels with normal tryptase suggesting a non-mast-cell-mediated histamine elevation. Both were responsive to low-Histamine diet (LHD) as a primary treatment.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2022 Category: Allergy & Immunology Authors: A. Ricks, M. Khan, L. Yao Tags: M315 Source Type: research
