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Source: Advances in Therapy
Condition: Heart Failure
Management: Funding

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Cardiac and Hemodynamic Benefits: Mode of Action of Ivabradine in Heart Failure
Abstract Heart failure has seen a number of therapeutic advances in recent years. Despite this, heart failure is still related to increasing rates of morbidity, repeated hospitalizations, and mortality. Ivabradine is a recent treatment option for heart failure. It has a mode of action that includes reduction in heart rate, and leads to improvement in outcomes related to heart failure mortality and morbidity, as demonstrated by the results of the SHIFT trial in patients with systolic heart failure, functional classes II and III on the New York Heart Association classification, and left ventricular ejection fractio...
Source: Advances in Therapy - October 31, 2015 Category: Drugs & Pharmacology Source Type: research