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Source: Circulation
Condition: Heart Failure
Management: WHO
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Plasminogen Activator Inhibitor-1: A Novel Therapeutic Target for Hypertension?
Abstract
Hypertension is the most common reversible risk factor for stroke, myocardial infarction, and heart failure, affecting greater than 60 million individuals in the United State alone and 1 billion globally(1). According to the World Health Organization, hypertension is now the leading cause of preventable death worldwide(2). Importantly, the prevalence and complications of hypertension increase significantly with age. However, despite the availability of many anti-hypertensive agents of distinct pharmacologic classes and evidence-based guideline recommendations for step-wise, multi-drug regimens, control of...
Source: Circulation - October 3, 2013 Category: Cardiology Authors: Simon DI, Simon NM Tags: Circulation Source Type: research
