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Trends in Hospitalizations and Outcomes for Acute Cardiovascular Disease and Stroke: 1999-2011.
CONCLUSIONS: -Hospitalizations for acute cardiovascular disease and stroke from 1999 through 2011 declined more rapidly than for other conditions. For these conditions, mortality and readmission outcomes improved. PMID: 25135276 [PubMed - as supplied by publisher]
Source: Circulation - August 18, 2014 Category: Cardiology Authors: Krumholz HM, Normand SL, Wang Y Tags: Circulation Source Type: research

Does Myocardial Infarction Beget Atrial Fibrillation and Atrial Fibrillation Beget Myocardial Infarction?
Abstract Atrial fibrillation (AF) affects millions of people worldwide.(1) It is already known several decades that AF is not a benign condition, and it's associated with a 5-fold increased risk of stroke, 3-fold increased risk of heart failure, and doubling of risk of dementia and death.(2-4) Myocardial infarction, and coronary heart disease, are traditional risk factors of AF,(5) however, whether myocardial infarction is a consequence of AF, has not been studied in great detail yet. The focus of current treatment for AF is pointed towards prevention of stroke. This is of utmost importance; however the other card...
Source: Circulation - April 27, 2015 Category: Cardiology Authors: Vermond RA, Van Gelder IC, Crijns HJ, Rienstra M Tags: Circulation Source Type: research

Assessment of Cardiovascular Risk in Older Patients with Gout Initiating Febuxostat versus Allopurinol: A Population-Based Cohort Study.
Conclusions -Among a cohort of 99,744 older Medicare patients with gout, overall there was no difference in the risk of MI, stroke, new onset HF, coronary revascularization, or all-cause mortality between patients initiating febuxostat compared with allopurinol. However, there seemed to be a trend toward an increased, albeit not statistically significant, risk for all-cause mortality in patients who used febuxostat for over 3 years versus allopurinol for over 3 years. The risk of HF exacerbation was slightly lower in febuxostat initiators. PMID: 29899013 [PubMed - as supplied by publisher]
Source: Circulation - June 13, 2018 Category: Cardiology Authors: Zhang M, Solomon DH, Desai RJ, Kang EH, Liu J, Neogi T, Kim SC Tags: Circulation Source Type: research

The Study of Cardiovascular Health Outcomes in the Era of Claims Data: The Cardiovascular Health Study.
CONCLUSIONS: -The use of diagnostic codes from claims data as clinical events, especially when restricted to primary diagnoses, leads to an underestimation of event rates. Additionally, claims-based events data represent a composite endpoint that includes the outcome of interest and selected (misclassified) non-event hospitalizations. PMID: 26538580 [PubMed - as supplied by publisher]
Source: Circulation - November 4, 2015 Category: Cardiology Authors: Psaty BM, Delaney JA, Arnold AM, Curtis LH, Fitzpatrick AL, Heckbert SR, McKnight B, Ives D, Gottdiener JS, Kuller LH, Longstreth WT Tags: Circulation Source Type: research

Cost-Effectiveness of Catheter Ablation Versus Antiarrhythmic Drug Therapy in Atrial Fibrillation: The CABANA Randomized Clinical Trial
CONCLUSION: Catheter ablation of atrial fibrillation was economically attractive compared with drug therapy in the CABANA Trial overall at present benchmarks for health care value in the United States on the basis of projected incremental QALYs but not LYs alone.PMID:35726631 | DOI:10.1161/CIRCULATIONAHA.122.058575
Source: Circulation - June 21, 2022 Category: Cardiology Authors: Derek S Chew Yanhong Li Patricia A Cowper Kevin J Anstrom Jonathan P Piccini Jeanne E Poole Melanie R Daniels Kristi H Monahan Linda Davidson-Ray Tristram D Bahnson Hussein R Al-Khalidi Kerry L Lee Douglas L Packer Daniel B Mark CABANA Investigators Source Type: research

Comparison of Unibody and Non-Unibody Endografts for Abdominal Aortic Aneurysm Repair in Medicare Beneficiaries: The SAFE-AAA Study
CONCLUSIONS: In the SAFE-AAA Study, unibody endografts failed to meet noninferiority compared with non-unibody endografts with respect to aortic reintervention, rupture, and mortality. These data support the urgency of instituting a prospective longitudinal surveillance program for monitoring safety events related to aortic stent grafts.PMID:36866664 | DOI:10.1161/CIRCULATIONAHA.122.062123
Source: Circulation - March 3, 2023 Category: Cardiology Authors: Eric A Secemsky Yang Song Tianyu Sun Carmen Gacchina Johnson Megan Gatski Li Wang Andrew Farb Robert E Lee Aurko Shaw Jiaman Xu Robert W Yeh Source Type: research