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Source: International Journal of Cardiology
Condition: Heart Failure

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Total 126 results found since Jan 2013.

Stroke risk reduction with oral anticoagulation using CHADS-VASc in a Japanese AF population: a modeling analysis
Current clinical guidelines recommend that risk stratification for ischaemic stroke in patients with nonvalvular AF (NVAF) should be performed using the CHA2DS2-VASc score (Congestive heart failure, Hypertension, Age≥75years [double], Diabetes mellitus, previous thromboembolism [double], Vascular disease, Age 65–74 years, and female gender) to aid decision making for antithrombotic treatment, with a preference for Non-Vitamin K Oral Anticoagulants (NOACs) in those with CHA2DS2-VASc score ≥1. However, CHA2DS2-VASc score is not recommended in the 2014 Japanese Circulation Society (JCS) guidelines for patients with NVAF.
Source: International Journal of Cardiology - December 5, 2014 Category: Cardiology Authors: Keitaro Senoo, Deirdre A. Lane, Gregory Y.H. Lip Source Type: research

Diabetes mellitus and risk of ischemic stroke in patients with heart failure and no atrial fibrillation
The risk of ischemic stroke, systemic thromboembolism, and all-cause death among heart failure patients previously diagnosed with diabetes mellitus is poorly described. We evaluated the risk of these endpoints among heart failure patients without diagnosed atrial fibrillation according to the presence of diabetes mellitus.
Source: International Journal of Cardiology - February 2, 2016 Category: Cardiology Authors: Line Melgaard, Anders Gorst-Rasmussen, Peter Søgaard, Lars Hvilsted Rasmussen, Gregory Y.H. Lip, Torben Bjerregaard Larsen Source Type: research

Advanced interatrial block predicts new-onset atrial fibrillation and ischemic stroke in patients with heart failure: The “Bayes' Syndrome-HF” study
We examined the prevalence of IAB and whether advanced IAB could predict new-ons et AF and/or stroke in HF patients.
Source: International Journal of Cardiology - May 18, 2018 Category: Cardiology Authors: Luis Alberto Escobar-Robledo, Antoni Bay és-de-Luna, Josep Lupón, Adrian Baranchuk, Pedro Moliner, Manuel Martínez-Sellés, Elisabet Zamora, Marta de Antonio, Mar Domingo, Germán Cediel, Julio Núñez, Evelyn Santiago-Vacas, Antoni Bayés-Genís Source Type: research

Revascularisation therapies improve the outcomes of ischemic stroke patients with atrial fibrillation and heart failure
Atrial fibrillation (AF) and heart failure (HF) carry a poor prognosis in acute ischaemic stroke (AIS). The impact of revascularisation therapies on outcomes in these patients is not fully understood.
Source: International Journal of Cardiology - October 1, 2020 Category: Cardiology Authors: Tiberiu A. Pana, Mohamed O. Mohamed, Allan B. Clark, Eoin Fahy, Mamas A. Mamas, Phyo K. Myint Source Type: research

A general theory of acute and chronic heart failure
Abstract: Current concepts of heart failure propose multiple heterogeneous pathophysiological mechanisms. Recently a theoretical framework for understanding chronic heart failure was suggested. This paper develops this framework to include acute heart failure syndromes.We propose that all acute heart failure syndromes may be understood in terms of a relative fall in left ventricular stroke volume. The initial compensatory mechanism is frequently a tachycardia often resulting in a near normal cardiac output. In more severe forms a fall in cardiac output causes hypotension or cardiogenic shock. In chronic heart failure the s...
Source: International Journal of Cardiology - April 9, 2012 Category: Cardiology Authors: David H. MacIver, Mark J. Dayer, Andrew J.I. Harrison Tags: Reviews Source Type: research

Atrial fibrillation management, outcomes and predictors of stable disease in daily practice: Prospective non-interventional study
Conclusions: The relatively low proportion of stable patients and in particular, the high hospitalization and stroke rate indicate difficulties in everyday management of patients with AF.
Source: International Journal of Cardiology - April 4, 2012 Category: Cardiology Authors: Ralph F. Bosch, Wilhelm Kirch, Juergen-Detlef Theuer, David Pittrow, Annette Kohlhaußen, Stefan N. Willich, Hendrik Bonnemeier Tags: Original Articles Source Type: research

Screening for atrial fibrillation: If I was left to my own devices
Atrial fibrillation (AF) is established as the most prevalent clinical arrhythmia, and a major risk factor for stroke, death, heart failure, cognitive decline, and hospitalisation [1]. Ranking these complications is difficult, however ischemic stroke caused by AF is posing a significant burden to patients, their next of kin, to physicians and to the health care system. The stroke risk in AF patients can be markedly lowered by oral anticoagulation (OAC) treatment [2], but many patients with AF have few or no symptoms [3], hence health care contacts and arrhythmia detection might be lacking [4].
Source: International Journal of Cardiology - November 16, 2021 Category: Cardiology Authors: Emma Svennberg, Johan Engdahl Tags: Editorial Source Type: research

Prognostic importance of atrial fibrillation in asymptomatic aortic stenosis: The Simvastatin and Ezetimibe in Aortic Stenosis study
Conclusion: Rate of AF is moderate in asymptomatic AS. Longstanding but not episodic AF was, independently predictive of increased risk of heart failure and non-hemorrhagic stroke. New-onset AF was associated with cardiac decompensation.
Source: International Journal of Cardiology - October 13, 2011 Category: Cardiology Authors: Anders M. Greve, Eva Gerdts, Kurt Boman, Christa Gohlke-Baerwolf, Anne B. Rossebø, Christoph A. Nienaber, Simon Ray, Kenneth Egstrup, Terje R. Pedersen, Lars Køber, Ronnie Willenheimer, Kristian Wachtell Tags: Original Articles Source Type: research

Left ventricular hypertrophy reduction and clinical events. A meta-regression analysis of 14 studies in 12,809 hypertensive patients
Abstract: Background: Left ventricular hypertrophy (LVH) is an independent risk factor for clinical events (CE), and regression of LVH is associated with reduction of cardiovascular risk. However, whether a continuous relationship between reduction of LVH and risk of CE exists has not been investigated.Methods: Randomized clinical trials evaluating LVH at baseline and reporting quantitative LVH changes and CE, stroke or new onset heart failure) were included. Meta-regression analysis was performed to test the relationship between changes in LVH and incidence of the composite outcome (all-cause death, MI, stroke or new onse...
Source: International Journal of Cardiology - July 16, 2012 Category: Cardiology Authors: Pierluigi Costanzo, Gianluigi Savarese, Giuseppe Rosano, Francesca Musella, Laura Casaretti, Enrico Vassallo, Stefania Paolillo, Fabio Marsico, Giuseppe Rengo, Dario Leosco, Pasquale Perrone-Filardi Tags: Original Articles Source Type: research

Women hospitalized with atrial fibrillation: Gender differences, trends and outcome from a 20-year registry in a middle eastern country (1991–2010)
Conclusions: Women hospitalized with atrial fibrillation were older in age and had higher prevalence of co-morbid cardiovascular risk factors compared to men whereas, mortality and stroke rates were comparable.
Source: International Journal of Cardiology - November 19, 2012 Category: Cardiology Authors: Amar M. Salam, Hajar A. AlBinali, Abdul Wahid Al-Mulla, Nidal Asaad, Rajvir Singh, Awad Al-Qahtani, Jassim Al Suwaidi Tags: Original Articles Source Type: research

The CHA2DS2-VASc score predicts 320-slice CT-based coronary artery plaques and >50% stenosis in subjects with chronic and paroxysmal atrial fibrillation
The CHADS2 score is a simple score to evaluate the risk of occurrence of cerebral infarction in subjects with atrial fibrillation (AF) that includes the variables of age (≥75yrs), hypertension, diabetes mellitus, previous stroke, and heart failure. Furthermore the CHA2DS2-VASc score is a more detailed assessment scheme than the CHADS2 score to further stratify the risk of occurrence of cerebral infarction in subjects with AF considering the following factors; female sex, presence of vascular disease, and age (≥65yrs) as stroke risk factors. Since both CHADS2 score and CHA2DS2-VASc score include coronary risk factors, t...
Source: International Journal of Cardiology - January 23, 2014 Category: Cardiology Authors: Nobusada Funabashi, Masae Uehara, Hiroyuki Takaoka, Yoshio Kobayashi Tags: Online Letters to the Editor Source Type: research

Beyond age, the need for useful parameters to identify heart failure patients in sinus rhythm that can benefit from oral anticoagulation
It is still unclear whether oral anticoagulant or aspirin therapy is superior for patients with heart failure (HF) who are in sinus rhythm. The subanalyses of the warfarin vs. aspirin in Reduced Cardiac Ejection Fraction (WARCEF) trial, that have been recently published , were aimed to identify subgroups of patients with reduced left ventricular ejection fraction (LVEF≤35%) in sinus rhythm that may benefit from warfarin or aspirin. They showed that patients under 60years have an improved outcome with warfarin over aspirin concerning the composite outcome of ischemic stroke, intracerebral hemorrhage and overall death, wha...
Source: International Journal of Cardiology - January 23, 2014 Category: Cardiology Authors: Enrico Ammirati, Dacia Dalla Libera, Maria Frigerio Tags: Online Letters to the Editor Source Type: research

The value of CHADS score in predicting new-onset atrial fibrillation in Chinese patients with acute myocardial infarction
Previous studies have shown that new-onset atrial fibrillation (AF) in the setting of acute myocardial infarction (AMI) was associated with increased in-hospital and long term mortality [1,2]. Therefore, it was crucial to recognize the patients with AMI who were on the increased risk for developing new-onset AF. CHADS2 score (congestive heart failure, hypertension, age≥75years, diabetes and previous stroke or transient ischemic attack) was a very useful and convenient scoring system, which was widely used for the stroke risk stratification in the patients with non-valvular AF [3].
Source: International Journal of Cardiology - August 5, 2014 Category: Cardiology Authors: Xiaowei Zhang, Guangping Li, Zhiqiang Zhao, Yanmin Xu, Tong Liu Source Type: research

Relation between left ventricular ejection time and pulmonary hemodynamics in pulmonary hypertension
In patients with precapillary pulmonary hypertension (PH), stroke volume is preserved in the early stages of disease as the right ventricle (RV) adapts adequately to the increased afterload. At more evolved stages, adaptive mechanisms become inefficient and stroke volume decreases, progressing to right heart failure and death [1]. We have recently demonstrated that shortened left ventricular ejection time (LVET) is predictive of worse prognosis in precapillary PH with right heart failure [2]. However, the literature remains inconclusive regarding the exact impact of PH on LVET [3–6].
Source: International Journal of Cardiology - February 28, 2015 Category: Cardiology Authors: S. Günther, B. Sztrymf, L. Savale, E.M. Lau, D. Montani, P. Hervé, F. Lador, X. Jaïs, F. Parent, G. Simonneau, O. Sitbon, M. Humbert, D. Chemla Tags: Letter to the Editor Source Type: research