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Recurrent stroke and myocardial infarction in a young woman with severe osteoporosis and hyperparathyroidism
We have taken great interest in the recently published article entitled “ Effect of calcium or vitamin D supplementation on vascular outcomes: A meta-analysis of randomized controlled trial” . Likewise, since parathormone (PTH) is a vasoactive peptide, we, herein, wish to draw attention to the fact that primary hyperparathyroidism (pHPT) can –as well– be in association with increased risk of cardiovascular diseases (i.e. myocardial infarction (MI), heart failure, thrombosis or cardioembolism, hypertension), stroke and osteoporosis . In this regard, we exemplify the clinical scenario of one of our pertinent patients.
Source: International Journal of Cardiology - January 21, 2014 Category: Cardiology Authors: Murat Kara, Levent Özçakar, Hatice Gözde Sümer, Timur Ekiz, Sibel Özbudak Demir, Ayşen Akıncı Tags: Online Letters to the Editor Source Type: research

Stroke risk reduction with oral anticoagulation using CHADS-VASc in a Japanese AF population: a modeling analysis
Current clinical guidelines recommend that risk stratification for ischaemic stroke in patients with nonvalvular AF (NVAF) should be performed using the CHA2DS2-VASc score (Congestive heart failure, Hypertension, Age≥75years [double], Diabetes mellitus, previous thromboembolism [double], Vascular disease, Age 65–74 years, and female gender) to aid decision making for antithrombotic treatment, with a preference for Non-Vitamin K Oral Anticoagulants (NOACs) in those with CHA2DS2-VASc score ≥1. However, CHA2DS2-VASc score is not recommended in the 2014 Japanese Circulation Society (JCS) guidelines for patients with NVAF.
Source: International Journal of Cardiology - December 5, 2014 Category: Cardiology Authors: Keitaro Senoo, Deirdre A. Lane, Gregory Y.H. Lip Source Type: research