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Questionnaire-based exposome-wide association studies (ExWAS) reveal expected and novel risk factors associated with cardiovascular outcomes in the Personalized Environment and Genes Study
In conclusion, using statistics and machine learning, these findings identify novel potential risk factors for CVD, enable hypothesis generation, provide insights into the complex relationships between risk factors and CVD, and highlight the importance of considering multiple exposures when examining CVD outcomes.PMID:35605674 | DOI:10.1016/j.envres.2022.113463
Source: Atherosclerosis - May 23, 2022 Category: Cardiology Authors: Eunice Y Lee Farida Akhtari John S House Ross J Simpson Charles P Schmitt David C Fargo Shepherd H Schurman Janet E Hall Alison A Motsinger-Reif Source Type: research

A causal relationship between irritability and cardiovascular diseases: a Mendelian randomization study
CONCLUSION: Our findings support the first genetic evidence of the causality of genetically predicted irritability with the risk of developing into CVDs. Our results deliver a viewpoint that more early active interventions to manage an individual's anger and related unhealthy lifestyle habits are needed to prevent the occurrence of adverse cardiovascular events.PMID:37324625 | PMC:PMC10267866 | DOI:10.3389/fcvm.2023.1174329
Source: Atherosclerosis - June 16, 2023 Category: Cardiology Authors: Dihui Cai Yin Fu Yongfei Song Hui Lin Yanna Ba Jiangfang Lian Source Type: research

Effects of colchicine on major adverse cardiac events in next 6-month period after acute coronary syndrome occurrence; a randomized placebo-control trial
CONCLUSION: The addition of colchicine to standard medical therapy in ACS patients significantly reduces MACE occurrence and improves survival rate over the time.PMID:34876021 | DOI:10.1186/s12872-021-02393-9
Source: Atherosclerosis - December 8, 2021 Category: Cardiology Authors: Mehdi Akrami Peyman Izadpanah Mehdi Bazrafshan Unes Hatamipour Navid Nouraein Hamed Bazrafshan Drissi Alireza Manafi Source Type: research

Clinical Outcomes of Acute Myocardial Infarction Hospitalizations with Systemic Lupus Erythematosus: An Analysis of Nationwide Readmissions Database
CONCLUSION: Patients with AMI and SLE had higher inpatient mortality during the index hospitalization and higher 30-day hospital readmissions compared to AMI patients without SLE. There were no significant differences in most of the other major inpatient outcomes between the two cohorts.PMID:34936910 | DOI:10.1016/j.cpcardiol.2021.101086
Source: Atherosclerosis - December 22, 2021 Category: Cardiology Authors: Shazib Sagheer Pallav Deka Dola Pathak Umair Khan Syeda Humna Zaidi Anum Akhlaq James Blankenship Ann Annis Source Type: research

Effect of a low dose of empagliflozin on short-term outcomes in type 2 diabetics with acute coronary syndrome after percutaneous coronary intervention
CONCLUSION: The results of this study showed that adding low dose empagliflozin to standard care of ACS diabetic patients after PCI was associated with no significant reduction in negative cardiovascular outcomes during 6 months.PMID:35537720 | DOI:10.15537/smj.2022.43.5.20220018
Source: Atherosclerosis - May 10, 2022 Category: Cardiology Authors: Seyed Mohammad H Adel Fateme Jorfi Hoda Mombeini Homeira Rashidi Saad Fazeli Source Type: research

A Randomized Controlled Trial Evaluating Outcome Impact of Cilostazol in Patients with Coronary Artery Disease or at a High Risk of Cardiovascular Disease
In conclusion, these results suggest cilostazol may have beneficial effects in patients with CAD or at a high risk of CV disease.PMID:35743723 | DOI:10.3390/jpm12060938
Source: Atherosclerosis - June 24, 2022 Category: Cardiology Authors: Jia-Ling Lin Wei-Kung Tseng Po-Tseng Lee Cheng-Han Lee Shih-Ya Tseng Po-Wei Chen Hsien-Yuan Chang Ting-Hsing Chao Source Type: research