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Source: Atherosclerosis
Condition: Heart Failure
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Total 212 results found since Jan 2013.
The Potential Cardiometabolic Effects of Long-Chain Omega-3 Polyunsaturated Fatty Acids: Recent Updates and Controversies
Adv Nutr. 2023 Apr 7:S2161-8313(23)00283-1. doi: 10.1016/j.advnut.2023.03.014. Online ahead of print.ABSTRACTVarious health-related effects of long-chain (LC) omega-3 polyunsaturated fatty acids (PUFAs), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been suggested. LC omega-3 PUFAs reduce triglyceride levels and have anti-inflammatory, immunomodulatory, antiplatelet, and vascular protective effects. Controversially, they might help in restoring glucose homeostasis via the gut microbiota. However, previous studies have not shown the clear benefits of LC omega-3 PUFAs for cardiovascular diseases. REDUCE-IT...
Source: Atherosclerosis - April 9, 2023 Category: Cardiology Authors: Jae Hyun Bae Hyunjung Lim Soo Lim Source Type: research
For Your Eyes Only: 007 Tips for the Management of Cardiovascular Risk Factors in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis
J Rheumatol. 2023 Apr 15:jrheum.2023-0219. doi: 10.3899/jrheum.2023-0219. Online ahead of print.ABSTRACTPremature atherosclerosis has been observed during the course of different systemic inflammatory diseases, such as rheumatoid arthritis (RA), systemic lupus erythematosus, and antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV).1-3 As a result, cardiovascular (CV) events, including myocardial infarction, stroke, heart failure, coronary artery disease, and death, occur 1.65 to 3 times more commonly in patients with AAV as compared to the general population, and the risk appears to be highest in the firs...
Source: Atherosclerosis - April 15, 2023 Category: Cardiology Authors: Jan Willem Cohen Tervaert Source Type: research
How much does hypertension in pregnancy affect the risk of future cardiovascular events?
Eur Heart J Suppl. 2023 Apr 21;25(Suppl B):B111-B113. doi: 10.1093/eurheartjsupp/suad085. eCollection 2023 Apr.ABSTRACTHypertensive disorders in pregnancy (HDP) include essential (or secondary) hypertension occurring before 20 weeks of gestation or in women already on antihypertensive therapy prior to pregnancy, gestational hypertension, developing after 20 weeks of gestation without significant proteinuria, and pre-eclampsia or AH onset after 20 weeks of pregnancy in the presence of proteinuria. The development of HDP is associated with a higher incidence of long-term cardiovascular (CV) adverse events, such as myocardial...
Source: Atherosclerosis - April 24, 2023 Category: Cardiology Authors: Gian Francesco Mureddu Source Type: research
Pollution from fine particulate matter and atherosclerosis: A narrative review
Environ Int. 2023 Apr 10;175:107923. doi: 10.1016/j.envint.2023.107923. Online ahead of print.ABSTRACTAccording to the WHO, the entire global population is exposed to air pollution levels higher than recommended for health preservation. Air pollution is a complex mixture of nano- to micro-sized particles and gaseous components that poses a major global threat to public health. Among the most important air pollutants, causal associations have been established between particulate matter (PM), mainly < 2.5 μm, and cardiovascular diseases (CVD), i.e., hypertension, coronary artery disease, ischemic stroke, congestive heart...
Source: Atherosclerosis - April 29, 2023 Category: Cardiology Authors: Chiara Macchi Cesare R Sirtori Alberto Corsini Pier Mannuccio Mannucci Massimiliano Ruscica Source Type: research
Mesenchymal stem cell-derived exosomes in cardiovascular and cerebrovascular diseases: From mechanisms to therapy
Biomed Pharmacother. 2023 May 2;163:114817. doi: 10.1016/j.biopha.2023.114817. Online ahead of print.ABSTRACTCardiovascular and cerebrovascular diseases (CVDs) remain an intractable problem and have high morbidity and mortality worldwide, as well as substantial health and economic burdens, representing an urgent clinical need. In recent years, the focus of research has shifted from the use of mesenchymal stem cells (MSCs) for transplantation to the use of their secretory exosomes (MSC-exosomes) for the treatment of numerous CVDs, including atherosclerosis, myocardial infarction (MI), heart failure (HF), ischemia/reperfusio...
Source: Atherosclerosis - May 4, 2023 Category: Cardiology Authors: Yanhong Pan Weipeng Wu Xiaoxin Jiang Yunhong Liu Source Type: research
Spleen tyrosine kinase (SYK) signals are implicated in cardio-cerebrovascular diseases
Heliyon. 2023 Apr 22;9(5):e15625. doi: 10.1016/j.heliyon.2023.e15625. eCollection 2023 May.ABSTRACTPost-translational modifications regulate numerous biochemical reactions and functions through covalent attachment to proteins. Phosphorylation, acetylation and ubiquitination account for over 90% of all reported post-translational modifications. As one of the tyrosine protein kinases, spleen tyrosine kinase (SYK) plays crucial roles in many pathophysiological processes and affects the pathogenesis and progression of various diseases. SYK is expressed in tissues outside the hematopoietic system, especially the heart, and is i...
Source: Atherosclerosis - May 14, 2023 Category: Cardiology Authors: Mohan Li Pengbo Wang Yuanming Zou Wenbin Wang Yuanhui Zhao Mengke Liu Jianlong Wu Ying Zhang Naijin Zhang Yingxian Sun Source Type: research
U-shaped association between the triglyceride-glucose index and atrial fibrillation incidence in a general population without known cardiovascular disease
CONCLUSIONS: A U-shaped association between the TyG index and AF incidence is observed in Americans without known cardiovascular diseases. Female sex may be a modifier in the association between the TyG index and AF incidence.PMID:37208737 | DOI:10.1186/s12933-023-01777-9
Source: Atherosclerosis - May 19, 2023 Category: Cardiology Authors: Xiao Liu Ayiguli Abudukeremu Yuan Jiang Zhengyu Cao Maoxiong Wu Jianyong Ma Runlu Sun Wanbing He Zhiteng Chen Yangxin Chen Peng Yu Wengen Zhu Yuling Zhang Jingfeng Wang Source Type: research
Neighborhood socioeconomic deprivation and individual-level socioeconomic status are associated with dopamine-mediated changes to monocyte subset CCR2 expression via a cAMP-dependent pathway
Brain Behav Immun Health. 2023 May 14;30:100640. doi: 10.1016/j.bbih.2023.100640. eCollection 2023 Jul.ABSTRACTSocial determinants of health (SDoH) include socioeconomic, environmental, and psychological factors that impact health. Neighborhood socioeconomic deprivation (NSD) and low individual-level socioeconomic status (SES) are SDoH that associate with incident heart failure, stroke, and cardiovascular mortality, but the underlying biological mechanisms are not well understood. Previous research has demonstrated an association between NSD, in particular, and key components of the neural-hematopoietic-axis including amyg...
Source: Atherosclerosis - May 30, 2023 Category: Cardiology Authors: Yvonne Baumer Mario A Pita Briana S Turner Andrew S Baez Lola R Ortiz-Whittingham Cristhian A Gutierrez-Huerta Sam J Neally Nicole Farmer Valerie M Mitchell Billy S Collins Tiffany M Powell-Wiley Source Type: research
Cognitive Impairment in Patients With Cardiac Disease: Implications for Clinical Practice
Stroke. 2023 Jun 5. doi: 10.1161/STROKEAHA.123.040499. Online ahead of print.ABSTRACTCognitive impairment is common in patients with cardiovascular disease. One in 3 patients presenting at cardiology clinics have some degree of cognitive impairment, depending on the cardiac condition, comorbidities, and age. In up to half of these cases cognitive impairment may go unrecognized; however, it may affect self-management and treatment adherence. The high prevalence of cognitive impairment in patients with cardiac disease is likely due to shared risk factors, as well as direct consequences of cardiac dysfunction on the brain. Mo...
Source: Atherosclerosis - June 5, 2023 Category: Cardiology Authors: Astrid C van Nieuwkerk Ronak Delewi Frank J Wolters Majon Muller Mat Daemen Geert Jan Biessels Heart-Brain Connection Consortium Source Type: research
Blood phytosterols in relation to cardiovascular diseases and mediating effects of blood lipids and hematological traits: a Mendelian randomization analysis
CONCLUSION: The study suggests that genetic predisposition to higher blood total sitosterol is linked to a greater risk of major CVDs. Moreover, blood nonHDL-C and apolipoprotein B might mediate a significant proportion of the associations between sitosterol and coronary diseases.PMID:37270173 | DOI:10.1016/j.metabol.2023.155611
Source: Atherosclerosis - June 3, 2023 Category: Cardiology Authors: Yimin Zhao Zhenhuang Zhuang Yueying Li Wendi Xiao Zimin Song Ninghao Huang Wenxiu Wang Xue Dong Jinzhu Jia Tao Huang Source Type: research
