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Source: Atherosclerosis
Condition: Heart Failure
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Total 212 results found since Jan 2013.
Novel biomarkers and emerging tools to identify causal molecular pathways in hypertension and associated cardiovascular diseases
Kardiol Pol. 2023 Feb 5. doi: 10.33963/KP.a2023.0037. Online ahead of print.ABSTRACTHypertension (HT) is a modifiable risk factor for life-threatening cardiovascular diseases (CVDs) including coronary artery disease, heart failure or stroke. Despite significant progress in understanding of the pathophysiological mechanisms of the disease, the molecular pathways targeted by HT treatment still remain largely unchanged. This warrants the necessity for searching novel biomarkers, which are causally related to persistent high blood pressure (BP) and may be pharmacologically targeted. Data from large-scale biobanks, containing h...
Source: Atherosclerosis - February 5, 2023 Category: Cardiology Authors: Ewelina J ózefczuk Tomasz J Guzik Mateusz Siedlinski Source Type: research
Copper homeostasis and copper-induced cell death in the pathogenesis of cardiovascular disease and therapeutic strategies
Cell Death Dis. 2023 Feb 11;14(2):105. doi: 10.1038/s41419-023-05639-w.ABSTRACTCopper is a vital mineral, and an optimal amount of copper is required to support normal physiologic processes in various systems, including the cardiovascular system. Over the past few decades, copper-induced cell death, named cuproptosis, has become increasingly recognized as an important process mediating the pathogenesis and progression of cardiovascular disease (CVD), including atherosclerosis, stroke, ischemia-reperfusion injury, and heart failure. Therefore, an in-depth understanding of the regulatory mechanisms of cuproptosis in CVD may ...
Source: Atherosclerosis - February 11, 2023 Category: Cardiology Authors: Xinyue Chen Qi Cai Ruikai Liang Deju Zhang Xiao Liu Meiying Zhang Yan Xiong Minxuan Xu Qi Liu Pengyang Li Peng Yu Ao Shi Source Type: research
Bioactive Compounds (BACs): A Novel Approach to Treat and Prevent Cardiovascular Diseases
Curr Probl Cardiol. 2023 Feb 23:101664. doi: 10.1016/j.cpcardiol.2023.101664. Online ahead of print.ABSTRACTCardiovascular diseases (CVDs) are one of the leading disorders of serious death and cause huge economic loss to patients and society. It is estimated that about 18 million people have a high death ratio due to the incidence of CVDs such as (stroke, coronary heart disease, and non-ischemic heart failure). Bioactive compounds (BACs) are healthy nutritional ingredients providing beneficial effects and nutritional value to the human body. Epidemiological studies strongly shed light on several bioactive compounds that ar...
Source: Atherosclerosis - February 25, 2023 Category: Cardiology Authors: Syed Riaz Ud Din Sumbul Saeed Shahid Ullah Khan Mintao Zhong Source Type: research
Risk of Major Cardiovascular Disease after Exposure to Contrast Media: A Nationwide Population-Based Cohort Study on Dialysis Patients
Metabolites. 2023 Feb 13;13(2):266. doi: 10.3390/metabo13020266.ABSTRACTContrast associated kidney injury is caused by side effects of iodinated contrast media (ICM), including inflammation. Chronic inflammation among dialysis patient contributes to atherosclerosis, which leads to simultaneous conditions of the kidney, brain, and vasculature. Data to investigate the pathologic effects of ICM on cardiovascular complications in dialysis patients are lacking. Dialysis patients who had been exposed to ICM from computed tomography (ICM-CT) were allocated as the ICM-CT cohort (N = 3751), whereas dialysis patients without ICM exp...
Source: Atherosclerosis - February 25, 2023 Category: Cardiology Authors: Shih-Ting Huang Tung-Min Yu Chia-Hsin Chen Yun-Chung Cheng Ya-Wen Chuang Cheng-Hsu Cheng Jia-Sin Liu Chih-Cheng Hsu Ming-Ju Wu Source Type: research
Association of Serum BAFF Levels with Cardiovascular Events in ST-Segment Elevation Myocardial Infarction
CONCLUSIONS: This study suggests that higher BAFF levels in the acute phase are an independent predictor of the incidence of MACEs in patients with STEMI.PMID:36836225 | PMC:PMC9964977 | DOI:10.3390/jcm12041692
Source: Atherosclerosis - February 25, 2023 Category: Cardiology Authors: Ziyang Wang Yueying Wang Yuke Cui Zhiyong Chen Lei Yi Zhengbin Zhu Jingwei Ni Run Du Xiaoqun Wang Jinzhou Zhu Fenghua Ding Weiwei Quan Ruiyan Zhang Jian Hu Xiaoxiang Yan Source Type: research
Bioactive Compounds (BACs): A Novel Approach to Treat and Prevent Cardiovascular Diseases
Curr Probl Cardiol. 2023 Feb 23:101664. doi: 10.1016/j.cpcardiol.2023.101664. Online ahead of print.ABSTRACTCardiovascular diseases (CVDs) are one of the leading disorders of serious death and cause huge economic loss to patients and society. It is estimated that about 18 million people have a high death ratio due to the incidence of CVDs such as (stroke, coronary heart disease, and non-ischemic heart failure). Bioactive compounds (BACs) are healthy nutritional ingredients providing beneficial effects and nutritional value to the human body. Epidemiological studies strongly shed light on several bioactive compounds that ar...
Source: Atherosclerosis - February 25, 2023 Category: Cardiology Authors: Syed Riaz Ud Din Sumbul Saeed Shahid Ullah Khan Mintao Zhong Source Type: research
Outcomes of endovascular repair of infrarenal penetrating aortic ulcers
Conclusions: According to this registry data, endovascular repair of PAU is technically feasible with acceptable perioperative outcomes, but further studies investigating mid- and long-term data are needed before invasive treatment of PAU disease in an elderly and comorbid patient population should be recommended.PMID:36880201 | DOI:10.1024/0301-1526/a001060
Source: Atherosclerosis - March 7, 2023 Category: Cardiology Authors: Johannes Hatzl Christian-Alexander Behrendt Thomas Schmitz-Rixen Reinhart Thomas Grundmann Markus Steinbauer Dittmar B öckler Christian Uhl DIGG Investigators Source Type: research
Circulating ketone bodies and cardiovascular outcomes: the MESA study
CONCLUSION: The study found that elevated endogenous KB in a healthy community-based population is associated with a higher rate of CVD and mortality. Ketone bodies could serve as a potential biomarker for cardiovascular risk assessment.PMID:36881667 | DOI:10.1093/eurheartj/ehad087
Source: Atherosclerosis - March 7, 2023 Category: Cardiology Authors: Elad Shemesh Parag Anilkumar Chevli Tareq Islam Charles A German James Otvos Joseph Yeboah Fatima Rodriguez Christopher deFilippi Joao A C Lima Michael Blaha Ambarish Pandey Muthiah Vaduganathan Michael D Shapiro Source Type: research
Outcomes of endovascular repair of infrarenal penetrating aortic ulcers
Conclusions: According to this registry data, endovascular repair of PAU is technically feasible with acceptable perioperative outcomes, but further studies investigating mid- and long-term data are needed before invasive treatment of PAU disease in an elderly and comorbid patient population should be recommended.PMID:36880201 | DOI:10.1024/0301-1526/a001060
Source: Atherosclerosis - March 7, 2023 Category: Cardiology Authors: Johannes Hatzl Christian-Alexander Behrendt Thomas Schmitz-Rixen Reinhart Thomas Grundmann Markus Steinbauer Dittmar B öckler Christian Uhl DIGG Investigators Source Type: research
Clonal Hematopoiesis and the Heart: a Toxic Relationship
Curr Oncol Rep. 2023 Mar 15. doi: 10.1007/s11912-023-01398-1. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Clonal hematopoiesis (CH) refers to the expansion of hematopoietic stem cell clones and their cellular progeny due to somatic mutations, mosaic chromosomal alterations (mCAs), or copy number variants which naturally accumulate with age. CH has been linked to increased risk of blood cancers, but CH has also been linked to adverse cardiovascular outcomes.RECENT FINDINGS: A combination of clinical outcome studies and mouse models have offered strong evidence that CH mutations either correlate with or cause atheroscle...
Source: Atherosclerosis - March 15, 2023 Category: Cardiology Authors: Jeffrey L Jensen Saumya Easaw Travis Anderson Yash Varma Jiandong Zhang Brian C Jensen Catherine C Coombs Source Type: research
Complementary prognostic value of stress perfusion imaging and global coronary flow reserve derived from cardiovascular magnetic resonance: a long-term cohort study
CONCLUSIONS: During long-term follow-up, stress perfusion CMR and global CFR derived from CS flow measurement provided complementary prognostic value for prediction of cardiovascular events. Microvascular dysfunction or diffuse atherosclerosis as shown by impaired global CFR may play a role as important as that of ischemia due to epicardial coronary stenosis in the risk stratification of CAD patients.PMID:36927677 | PMC:PMC10018821 | DOI:10.1186/s12968-023-00930-3
Source: Atherosclerosis - March 17, 2023 Category: Cardiology Authors: Satoshi Nakamura Masaki Ishida Kei Nakata Masafumi Takafuji Shiro Nakamori Tairo Kurita Haruno Ito Kaoru Dohi Hajime Sakuma Source Type: research
ATP-binding cassette G1 membrane transporter-mediated cholesterol efflux capacity influences coronary atherosclerosis and cardiovascular risk in Rheumatoid Arthritis
CONCLUSION: ABCG1-CEC inversely associated with plaque burden and vulnerability, and plaque progression conditionally on cumulative inflammation and corticosteroid dose. ABCG1-CEC inversely associated with events specifically in patients with noncalcified plaques, lower inflammation and in prednisone users.PMID:36996698 | DOI:10.1016/j.jaut.2023.103029
Source: Atherosclerosis - March 30, 2023 Category: Cardiology Authors: George A Karpouzas Bianca Papotti Sarah R Ormseth Marcella Palumbo Elizabeth Hernandez Maria Pia Adorni Francesca Zimetti Matthew J Budoff Nicoletta Ronda Source Type: research
Association of non-HDL-C-to-HDL-C ratio with coronary lesions and its prognostic performance in first-onset NSTEMI
Conclusion: NON-HDL-C:HDL-C is associated with coronary lesions and prognosis in non-ST-segment elevation acute myocardial infarction.PMID:36994674 | DOI:10.2217/bmm-2022-0548
Source: Atherosclerosis - March 30, 2023 Category: Cardiology Authors: Qi Mao Jianhua Zhao Xiaohui Zhao Source Type: research
