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Source: Atherosclerosis
Condition: Heart Failure

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Total 212 results found since Jan 2013.

Percutaneous revascularization for atherosclerotic renal artery stenosis: a meta-analysis
CONCLUSIONS: Medication therapy alone is as effective and safe as PR.PMID:36263548 | DOI:10.26355/eurrev_202210_29884
Source: Atherosclerosis - October 20, 2022 Category: Cardiology Authors: Y Li W-H Cui J Wang X Chen C Zhang L-Z Zhu S-J Cui C-J Bian T Luo Source Type: research

Causal Relationships of Excessive Daytime Napping with Atherosclerosis and Cardiovascular Diseases: A Mendelian Randomization Study
CONCLUSION: Habitual daytime napping is causally associated with an increased risk of incident CVD primarily via the development of coronary atherosclerosis. An average napping duration of more than 60 minutes is associated with an elevated risk of CVD in all participants.PMID:36302037 | DOI:10.1093/sleep/zsac257
Source: Atherosclerosis - October 27, 2022 Category: Cardiology Authors: Jiayun Chen Jie Chen Tianren Zhu Yuanyuan Fu Io Hong Cheongi Kexin Yi Hui Wang Xue Li Source Type: research

The AIM2 Inflammasome: A Novel Biomarker and Target in Cardiovascular Disease
Pharmacol Res. 2022 Nov 1:106533. doi: 10.1016/j.phrs.2022.106533. Online ahead of print.ABSTRACTAbsent in melanoma 2(AIM2) is a cytoplasmic sensor that recognizes the double-strand DNA. AIM2 inflammasome is a protein platform in the cell that initiates innate immune responses by cleaving pro-caspase-1 and converting IL-1β and IL-18 to their mature forms. Additionally, AIM2 inflammasome promotes pyroptosis by converting Gasdermin-D(GSDMD) to GSDMD-N fragments. An increasing number of studies have indicated the important and decisive roles of the AIM2 inflammasome, IL-1β, and pyroptosis in cardiovascular diseases, such as...
Source: Atherosclerosis - November 4, 2022 Category: Cardiology Authors: Luping Du Xuyang Wang Siyuan Chen Xiaogang Guo Source Type: research

Artificial neuronal network analysis in investigating the relationship between oxidative stress and endoplasmic reticulum stress to address blocked vessels in cardiovascular disease
CONCLUSIONS: VPO1 and ATF4 might be potential biomarkers associated with coronary artery disease, especially in the follow-up and monitoring of treatment protocols, in addition to traditional risk factors.PMID:36381079 | PMC:PMC9636495 | DOI:10.5937/jomb0-33855
Source: Atherosclerosis - November 16, 2022 Category: Cardiology Authors: Fatma Kalay Toprak Muhammet Sait Hakan Ekmek çi Mine Kucur Bar ış İkitimur H üseyin Sönmez Zeynep G üngör Source Type: research

Diabetic retinopathy predicts cardiovascular disease independently of subclinical atherosclerosis in individuals with type 2 diabetes: A prospective cohort study
CONCLUSION: DR is a strong predictor of cardiovascular events in T2D individuals at primary CVD prevention, even after accounting for the presence of preclinical carotid atherosclerosis. These results may help to individualize CVD prevention strategies in T2D.PMID:36407461 | PMC:PMC9668891 | DOI:10.3389/fcvm.2022.945421
Source: Atherosclerosis - November 21, 2022 Category: Cardiology Authors: Esmeralda Castelblanco Minerva Granado-Casas Marta Hern ández Montserrat Pinyol Eudald Correig Josep Julve Marina Idalia Rojo-L ópez N úria Alonso Angelo Avogaro Emilio Ortega Didac Mauricio Source Type: research

Mechanism of Hypoxia-Mediated Smooth Muscle Cell Proliferation Leading to Vascular Remodeling
Biomed Res Int. 2022 Dec 24;2022:3959845. doi: 10.1155/2022/3959845. eCollection 2022.ABSTRACTVascular remodeling refers to changes in the size, contraction, distribution, and flow rate of blood vessels and even changes in vascular function. Vascular remodeling can cause cardiovascular and cerebrovascular diseases. It can also lead to other systemic diseases, such as pulmonary hypertension, pulmonary atherosclerosis, chronic obstructive pulmonary disease, stroke, and ascites of broilers. Hypoxia is one of the main causes of vascular remodeling. Prolonged hypoxia or intermittent hypoxia can lead to loss of lung ventilation,...
Source: Atherosclerosis - January 3, 2023 Category: Cardiology Authors: Xiaojuan Huang Elif Ece Akg ün Khalid Mehmood Hui Zhang Zhaoxin Tang Ying Li Source Type: research

Dual pathway inhibition for atherosclerotic cardiovascular disease: Recent advances
Kardiol Pol. 2022;80(12):1200-1210. doi: 10.33963/KP.a2022.0283.ABSTRACTAtherosclerotic cardiovascular disease (ASCVD), which includes coronary artery disease (CAD), cerebrovascular disease, and peripheral arterial disease (PAD) is associated with significant morbidity, mortality, and healthcare costs. Antiplatelet therapy has long been the mainstay of antithrombotic therapy for the prevention of first-ever and recurrent ASCVD events. More recently, however, randomized trials have demonstrated the benefits and cost-effectiveness of a dual pathway inhibition (DPI) strategy in acute and chronic ASCVD. When used in combinatio...
Source: Atherosclerosis - January 5, 2023 Category: Cardiology Authors: Stephanie Carlin Tim Ac de Vries Andrzej Budaj John Eikelboom Source Type: research

Air Pollution: Another Threat to HDL Function
Int J Mol Sci. 2022 Dec 24;24(1):317. doi: 10.3390/ijms24010317.ABSTRACTEpidemiological studies have consistently demonstrated a positive association between exposure to air pollutants and the incidence of cardiovascular disease, with the strongest evidence for particles with a diameter < 2.5 μm (PM2.5). Therefore, air pollution has been included among the modifiable risk factor for cardiovascular outcomes as cardiovascular mortality, acute coronary syndrome, stroke, heart failure, and arrhythmias. Interestingly, the adverse effects of air pollution are more pronounced at higher levels of exposure but were also sho...
Source: Atherosclerosis - January 8, 2023 Category: Cardiology Authors: Alice Ossoli Federica Cetti Monica Gomaraschi Source Type: research

Increased Risk of Cardiovascular Diseases in Rheumatoid Arthritis: A Systematic Review
This study systematically reviews various CV diseases that might occur with RA including heart failure (HF), coronary artery disease, acute coronary syndrome, ischemic heart disease, stroke, cardiac death, venous thromboembolism, and valvular diseases. The relation between these complications and RA is specifically assessed. Systematic search was carried out on literature reporting the risk of each of the CV diseases in RA patients from databases in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The databases searched were MEDLINE (through PubMed) and Google Scholar ...
Source: Atherosclerosis - January 12, 2023 Category: Cardiology Authors: Hadi Farhat Huma Irfan Kanmani Muthiah Namratha Pallipamu Sogand Taheri Suvedha S Thiagaraj Twisha S Shukla Sai Dheeraj Gutlapalli Sheiniz Giva Sai Sri Penumetcha Source Type: research

Multiple Prior Live Births are Associated with Cardiac Remodeling and Heart Failure Risk in Women
CONCLUSIONS: Greater number of live births are associated with worse cardiac structure and function. While there was no association with overall HF, a higher number of live births was associated with greater risk for incident HFrEF.PMID:36638956 | DOI:10.1016/j.cardfail.2022.12.014
Source: Atherosclerosis - January 13, 2023 Category: Cardiology Authors: Amy A Sarma Samantha M Paniagua Emily S Lau Dongyu Wang Elizabeth E Liu Martin G Larson Naomi M Hamburg Gary F Mitchell Jorge Kizer Bruce M Psaty Norrina B Allen A Titia Lely Ronald T Gansevoort Emily Rosenberg Kenneth Mukamal Emelia J Benjamin Ramachandr Source Type: research

Clinical Characteristics and Prognosis of MINOCA Caused by Atherosclerotic and Nonatherosclerotic Mechanisms Assessed by OCT
CONCLUSIONS: OCT identified a cause in 61.1% of MINOCA, in which Ath-MINOCA represents an important and distinct MINOCA subset. Ath-MINOCA were more common and associated with worse outcomes. (Incidence Rate of Heart Failure After Acute Myocardial Infarction With Optimal Treatment; NCT03297164) (Paradigm Shift in the Treatment of Patients With ACS; NCT02041650).PMID:36648054 | DOI:10.1016/j.jcmg.2022.10.023
Source: Atherosclerosis - January 17, 2023 Category: Cardiology Authors: Ming Zeng Chen Zhao Xiaoyi Bao Minghao Liu Luping He Yishuo Xu Wei Meng Yuhan Qin Ziqian Weng Boling Yi Dirui Zhang Shengfang Wang Xing Luo Ying Lv Xi Chen Qianhui Sun Xue Feng Zhanqun Gao Yanli Sun Abigail Demuyakor Ji Li Sining Hu Giulio Guagliumi Gary Source Type: research

Prognostic Implication of Small Dense LDL-Cholesterol Levels following Acute Coronary Syndrome
Conclusions: Small dense LDL-cholesterol level was a significant risk factor for cardiovascular events following presentations of acute coronary syndrome.PMID:36676782 | DOI:10.3390/medicina59010158
Source: Atherosclerosis - January 21, 2023 Category: Cardiology Authors: Teruhiko Imamura Masakazu Hori Nikhil Narang Hiroshi Ueno Koichiro Kinugawa Source Type: research