Stroke RSS Page 10

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Source: Atherosclerosis
Condition: Heart Failure

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Total 212 results found since Jan 2013.

Health-related quality of life and associated factors among hypertensive patients
CONCLUSIONS: Hypertensives had low HRQOL scores in all domains. Factors affecting their HRQOL should be taken into account when treating these patients.PMID:36027221 | DOI:10.1097/01.hjh.0000837808.51473.2f
Source: Atherosclerosis - August 26, 2022 Category: Cardiology Authors: Duy Tran Cong Hoa Chau Ngoc Source Type: research

State of target organs damage and prevalence of clinical associated conditions in patients with a hypertensive crisis and uncontrolled hypertension. (pilot study)
CONCLUSIONS: Patients with hypertensive crisis have more pronounced damage of target organs, as well as the most frequent prevalence of associated clinical conditions.PMID:36027392 | DOI:10.1097/01.hjh.0000838492.53623.dc
Source: Atherosclerosis - August 26, 2022 Category: Cardiology Authors: Tatyana Solntseva Anastasia Denisova Olga Sivakova Irina Chazova Source Type: research

Reduction in the risk of major adverse cardiovascular events with the BET protein inhibitor apabetalone in patients with recent acute coronary syndrome, type 2 diabetes, and moderate to high likelihood of non-alcoholic fatty liver disease
CONCLUSIONS: Amongst patients with T2DM, recent ACS, and a moderate-to-high likelihood of advanced liver fibrosis, apabetalone was associated with a significantly lower rate of ischemic MACE and HHF and attenuated the increase in hepatic FS over time.PMID:36039183 | PMC:PMC9419281 | DOI:10.1016/j.ajpc.2022.100372
Source: Atherosclerosis - August 30, 2022 Category: Cardiology Authors: Peter P Toth Gregory G Schwartz Stephen J Nicholls Aziz Khan Michael Szarek Henry N Ginsberg Jan O Johansson Kamyar Kalantar-Zadeh Ewelina Kulikowski Ken Lebioda Norman C W Wong Michael Sweeney Kausik K Ray BETonMACE Investigators Source Type: research

Similarities and differences in systemic risk factors for retinal artery occlusion and retinal vein occlusion: A nationwide case-control study
CONCLUSION: Differences in the level of associations with the included risk factors suggests differences in the pathophysiologies of the two diseases. The main pathophysiology associated with RAO was atherosclerosis, whereas the main pathophysiology associated with RVO was changes in the pressure gradients of the eyes.PMID:36056288 | DOI:10.1007/s10792-022-02483-3
Source: Atherosclerosis - September 2, 2022 Category: Cardiology Authors: Marie Ørskov Henrik Vorum Torben Bjerregaard Larsen Gregory Y H Lip Toke Bek Flemming Skj øth Source Type: research

CHARGE-AF: A useful score for atrial fibrillation prediction?
Curr Cardiol Rev. 2022 Sep 1. doi: 10.2174/1573403X18666220901102557. Online ahead of print.ABSTRACTAtrial fibrillation (AF) is the commonest arrhythmia in clinical practice and is associated with increased morbidity and mortality. Various predictive scores for new-onset AF have been proposed, but so far none has been widely used in clinical practice. CHARGE-AF score was developed from a pooled diverse population from three large cohorts (Atherosclerosis Risk in Communities study, Cardiovascular Health Study and Framingham Heart Study). A simple 5-year predictive model includes the variables of age, race, height, weight, s...
Source: Atherosclerosis - September 3, 2022 Category: Cardiology Authors: Christos Goudis Stylianos Daios Fotis Dimitriadis Tong Liu Source Type: research

Serum cholesterol loading capacity on macrophages is linked to coronary atherosclerosis and cardiovascular event risk in rheumatoid arthritis
CONCLUSION: CLC was linked to long-term cardiovascular event risk in RA and associated with high-risk low attenuation and obstructive coronary plaque presence and burden in bDMARD non-users. Its prospective validation as a predictive biomarker may be, therefore, warranted.PMID:36113961 | DOI:10.1136/rmdopen-2022-002411
Source: Atherosclerosis - September 16, 2022 Category: Cardiology Authors: George Athanasios Karpouzas Bianca Papotti Sarah Ormseth Marcella Palumbo Elizabeth Hernandez Maria Pia Adorni Francesca Zimetti Matthew Budoff Nicoletta Ronda Source Type: research

Higher mortality in acute coronary syndrome patients without standard modifiable risk factors: Results from a global meta-analysis of 1,285,722 patients
CONCLUSION: In this study level meta-analysis, SMuRF-less ACS patients demonstrate higher mortality compared with patients with at least one traditional atherosclerotic risk factor. Underuse of guideline-directed medical therapy amongst SMuRF-less patients is concerning. Unraveling novel risk factors amongst SMuRF-less individuals is the next important step.SUMMARY: Standard modifiable cardiovascular risk factors (SMuRF), comprising diabetes mellitus, hyperlipidemia, hypertension, and smoking, are often used for risk stratification in acute coronary syndrome (ACS). Recent studies showed an increasing proportion of SMuRF-le...
Source: Atherosclerosis - September 30, 2022 Category: Cardiology Authors: Gwyneth Kong Yip Han Chin Bryan Chong Rachel Sze Jen Goh Oliver Zi Hern Lim Cheng Han Ng Mark Muthiah Roger Foo Stephen T Vernon Poay Huan Loh Mark Y Chan Nicholas W S Chew Gemma A Figtree Source Type: research

RNA modifications in aging-associated cardiovascular diseases
Aging (Albany NY). 2022 Sep 29;14(undefined). doi: 10.18632/aging.204311. Online ahead of print.ABSTRACTCardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide that bears an enormous healthcare burden and aging is a major contributing factor to CVDs. Functional gene expression network during aging is regulated by mRNAs transcriptionally and by non-coding RNAs epi-transcriptionally. RNA modifications alter the stability and function of both mRNAs and non-coding RNAs and are involved in differentiation, development, and diseases. Here we review major chemical RNA modifications on mRNAs and non-co...
Source: Atherosclerosis - September 30, 2022 Category: Cardiology Authors: Xinyu Yang Priyanka Gokulnath H Immo Lehmann Zhitao Hou Sun Yang Liangzhen You Guoxia Zhang Yanwei Xing Ji Lei Guoping Li Shuwen Guo Hongcai Shang Source Type: research

Association of Bariatric Surgery With Cardiovascular Outcomes in Adults With Severe Obesity and Nonalcoholic Fatty Liver Disease
CONCLUSIONS AND RELEVANCE: Results of this study suggest that, compared with nonsurgical care, bariatric surgery was associated with significant reduction in CVD risk in individuals with severe obesity and NAFLD.PMID:36205997 | DOI:10.1001/jamanetworkopen.2022.35003
Source: Atherosclerosis - October 7, 2022 Category: Cardiology Authors: Mohamed I Elsaid You Li John F P Bridges Guy Brock Carlos D Minacapelli Vinod K Rustgi Source Type: research

Sodium-Glucose Cotransporter-2 Inhibitors: Impact on Atherosclerosis and Atherosclerotic Cardiovascular Disease Events
Heart Fail Clin. 2022 Oct;18(4):597-607. doi: 10.1016/j.hfc.2022.03.007.ABSTRACTSodium-glucose cotransporter-2 inhibitors (SGLT-2i) improve the risk for heart and kidney failure. However, their effects on major atherosclerotic cardiovascular events (MACE) are less clear. Although outcomes trials of drugs for diabetes were not powered to prove superiority, the totality of trial data yields an estimate of ∼11% relative reduction for MACE (HR 0.89, 95%CI 0.82-0.96) and neutral on stroke (HR 0.92, 95%CI 0.79-1.08). In animal models, SGLT-2i favorably affects plaque size, composition, and inflammatory pathways; human data in ...
Source: Atherosclerosis - October 10, 2022 Category: Cardiology Authors: Adam J Nelson Josephine L Harrington Ahmed A Kolkailah Neha J Pagidipati Darren K McGuire Source Type: research

Influence of clonal hematopoiesis on non-hematological diseases and aging processes
Inn Med (Heidelb). 2022 Oct 10. doi: 10.1007/s00108-022-01409-6. Online ahead of print.ABSTRACTThe occurrence of clonal hematopoiesis, caused by acquired somatic mutations of leukemia-associated genes in blood stem cells is very common in the population and increases with age. Besides an increased risk of developing myeloid neoplasms, an unexpected causal relationship between clonal hematopoiesis and cardiovascular diseases was recently discovered. Clonal hematopoiesis presents as a new independent and strong risk factor for cardiovascular diseases, such as atherosclerosis, coronary heart disease, heart failure, aortic val...
Source: Atherosclerosis - October 10, 2022 Category: Cardiology Authors: Michael A Rieger Source Type: research

Mediterranean Diet and Its Association with Cardiovascular Disease Risk Factors: A Scoping Review
Int J Environ Res Public Health. 2022 Oct 6;19(19):12762. doi: 10.3390/ijerph191912762.ABSTRACTAtherosclerosis is the underlying cause of cardiovascular diseases (CVD) and is interrelated to stroke, heart attack, and heart failure. The Mediterranean Diet (MedDiet) has been closely associated with reduced CVD morbidity and mortality, but research is not well explored for this relationship in individuals with diabetes (who experience greater CVD morbidity and mortality than individuals without diabetes). The aim of this review was to explore the literature related to the MedDiet and atherosclerosis and associated risk factor...
Source: Atherosclerosis - October 14, 2022 Category: Cardiology Authors: Leigh Ann Richardson Kenneth Izuora Arpita Basu Source Type: research

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