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Source: BMC Cancer
Condition: Brain Tumor
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Total 4 results found since Jan 2013.
High epiregulin expression in human U87 glioma cells relies on IRE1alpha and promotes autocrine growth through EGF receptor
Conclusion:
EREG may contribute to glioma progression under the control of IRE1alpha, as exemplified here by the autocrine proliferation loop mediated in U87 cells by the growth factor through ErbB1.
Source: BMC Cancer - December 13, 2013 Category: Cancer & Oncology Authors: Gregor AufArnaud JabouilleMaylis DeluginSylvaine GuéritRaphael PineauSophie NorthNatalia PlatonovaMarlène MaitreAlexandre FavereauxPeter VajkoczyMasaharu SenoAndreas BikfalviDmitri MinchenkoOleksandr MinchenkoMichel Moenner Source Type: research
High epiregulin expression in human U87 glioma cells relies on IRE1¿ and promotes autocrine growth through EGF receptor
Conclusion:
EREG may contribute to glioma progression under the control of IRE1alpha, as exemplified here by the autocrine proliferation loop mediated in U87 cells by the growth factor through ErbB1.
Source: BMC Cancer - December 13, 2013 Category: Cancer & Oncology Authors: Gregor AufArnaud JabouilleMaylis DeluginSylvaine GuéritRaphael PineauSophie NorthNatalia PlatonovaMarlène MaitreAlexandre FavereauxPeter VajkoczyMasaharu SenoAndreas BikfalviDmitri MinchenkoOleksandr MinchenkoMichel Moenner Source Type: research
The roles of Notch1 expression in the migration of intrahepatic cholangiocarcinoma
Conclusion:
Notch1 may induce a migratory effect in ICC by causing an epithelial-mesenchymal transition and activating Rac1 and could serve as a novel diagnostic and therapeutic target in patients with ICC.
Source: BMC Cancer - May 20, 2013 Category: Cancer & Oncology Authors: Qi ZhouYafeng WangBaogang PengLijian LiangJiaping Li Source Type: research
Increased paired box transcription factor 8 has a survival function in Glioma
Conclusions:
PAX8 is increased in the majority of glioblastomas and promoted cell survival. Because PAX8 is absent in normal brain tissue, it may be a promising therapeutic target pathway for treating aggressive gliomas.
Source: BMC Cancer - March 6, 2014 Category: Cancer & Oncology Authors: Noelyn HungYu-Jen ChenAhmad TahaMagnus OlivecronaRonald BoetAnna WilesTracy WarrAlisha ShawRamona EiholzerBruce BaguleyMichael EcclesAntony BraithwaiteMartin MacFarlaneJanice RoydsTania Slatter Source Type: research
