Filtered By:
Specialty: Cancer & Oncology
Condition: Heart Attack
Nutrition: Antidoxidants
This page shows you your search results in order of date.
Order by Relevance | Date
Total 1 results found since Jan 2013.
Intermittent treatment with farnesyltransferase inhibitor and sulforaphane improves cellular homeostasis in Hutchinson-Gilford progeria fibroblasts.
We report that co-administration of both drugs exerts a synergistic and additive positive effect on autophagy activity but was cytotoxic to HGPS cells. In contrast, intermittent treatment with lonafarnib followed by sulforaphane separately and in repeated cycles rescued the HGPS cellular phenotype. We propose that intermittent treatment with FTI and SFN separately might be a promising therapeutic avenue for children with HGPS.
PMID: 28740020 [PubMed - as supplied by publisher]
Source: Oncotarget - July 26, 2017 Category: Cancer & Oncology Tags: Oncotarget Source Type: research
