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Comparative Effects of Sodium-Glucose Cotransporter 2 Inhibitor and Thiazolidinedione Treatment on Risk of Stroke among Patients with Type 2 Diabetes Mellitus
CONCLUSION: In this real-world data, the risk of stroke was comparable in T2DM patients treated with SGLT-2i or TZD.PMID:35130688 | DOI:10.4093/dmj.2021.0160
Source: Diabetes and Metabolism Journal - February 8, 2022 Category: Endocrinology Authors: Seung Eun Lee Hyewon Nam Han Seok Choi Hoseob Kim Dae-Sung Kyoung Kyoung-Ah Kim Source Type: research

Myocardial Infarction, Stroke, and All-Cause Mortality According to Low-Density Lipoprotein Cholesterol Level in the Elderly, a Nationwide Study
CONCLUSION: Among the elderly, lower LDL-C was associated with decreased risks of MI and stroke. Lower LDL-C achieved by statins in the elderly was associated with a decreased risk of all-cause death during follow-up, suggesting that LDL-C paradox for the premature death risk in the elderly should not be applied to statin users. Intensive statin therapy should not be hesitated for older adults with cardiovascular risk factors including diabetes.PMID:35255552 | DOI:10.4093/dmj.2021.0225
Source: Diabetes and Metabolism Journal - March 7, 2022 Category: Endocrinology Authors: You-Bin Lee Minji Koo Eunjin Noh Soon Young Hwang Jung A Kim Eun Roh So-Hyeon Hong Kyung Mook Choi Sei Hyun Baik Geum Joon Cho Hye Jin Yoo Source Type: research

The Risk of Myocardial Infarction and Ischemic Stroke According to Waist Circumference in 21,749,261 Korean Adults: A Nationwide Population-Based Study.
CONCLUSION: WC had a significant linear relationship with the risk of MI and IS and the risk began to increase from a WC that was lower than expected. PMID: 30604597 [PubMed - as supplied by publisher]
Source: Diabetes and Metabolism Journal - January 5, 2019 Category: Endocrinology Tags: Diabetes Metab J Source Type: research

Metabolic Syndrome Severity Score for Predicting Cardiovascular Events: A Nationwide Population-Based Study from Korea.
Conclusion: The newly developed age- and sex-specific continuous MS score for the Korean population is an independent predictor of ischemic stroke and MI in Korean middle-aged adults even after adjusting for confounding factors. PMID: 33516167 [PubMed - as supplied by publisher]
Source: Diabetes and Metabolism Journal - February 2, 2021 Category: Endocrinology Tags: Diabetes Metab J Source Type: research

Cardiovascular Safety of Sodium Glucose Cotransporter 2 Inhibitors as Add-on to Metformin Monotherapy in Patients with Type 2 Diabetes Mellitus.
Conclusion: SGLT2 inhibitors can be a good second-line drug to reduce the incidence of cardiovascular diseases compared with DPP-4 inhibitors or sulfonylureas in people with type 2 diabetes mellitus. PMID: 33120439 [PubMed - as supplied by publisher]
Source: Diabetes and Metabolism Journal - October 31, 2020 Category: Endocrinology Tags: Diabetes Metab J Source Type: research

Being Metabolically Healthy, the Most Responsible Factor for Vascular Health.
Authors: Rhee EJ Abstract The prevalence of obesity is rapidly increasing worldwide. One-thirds of world population is suffering from the deleterious effects of excessive fat and adipose tissue in their body. At the same time, the average life expectancy is becoming higher and higher every decade. Therefore, living healthy and longer is the dream for everyone. Simply being obese is not the primary cause for the consequence of obesity; rather, the depot where the fat is accumulated, is the primary key for the deleterious effects of obesity. Results from historical research suggest that visceral fat increases the ris...
Source: Diabetes and Metabolism Journal - March 6, 2018 Category: Endocrinology Tags: Diabetes Metab J Source Type: research

Asian Subpopulations May Exhibit Greater Cardiovascular Benefit from Long-Acting Glucagon-Like Peptide 1 Receptor Agonists: A Meta-Analysis of Cardiovascular Outcome Trials.
CONCLUSION: Long-acting GLP-1 RAs reduced risks of MACE and CV deaths in high-risk patients with type 2 diabetes mellitus. Our findings of a particularly effective reduction in CV events with GLP-1 RA in Asian populations merits further exploration and dedicated trials in specific populations. PMID: 30604598 [PubMed - as supplied by publisher]
Source: Diabetes and Metabolism Journal - January 5, 2019 Category: Endocrinology Tags: Diabetes Metab J Source Type: research

Increased Risk of Cardiovascular Disease and Mortality in Patients with Diabetes and Coexisting Depression: A Nationwide Population-Based Cohort Study.
Conclusion: Coexisting depression in patients with diabetes has a deleterious effect on the development of CVD and mortality. We suggest that more attention should be given to patients with diabetes who present with depressive symptoms. PMID: 33297602 [PubMed - as supplied by publisher]
Source: Diabetes and Metabolism Journal - December 13, 2020 Category: Endocrinology Tags: Diabetes Metab J Source Type: research

Association between Low-Density Lipoprotein Cholesterol Level and Cardiovascular Outcomes in Korean Adults: A Nationwide Cohort Study
CONCLUSION: We confirmed the incidence of CVD was increased in higher LDL-C range. The risk of CVD increased from ≥70 mg/dL of LDL-C in very high-risk and high-risk groups, and from ≥130 mg/dL of LDL-C in moderate-risk and low-risk groups in Korean adults.PMID:36727164 | DOI:10.4093/dmj.2021.0320
Source: Diabetes and Metabolism Journal - February 2, 2023 Category: Endocrinology Authors: Junghyun Noh Min Kyong Moon Eun-Jung Rhee Sang Hyun Park Hyeon Chang Kim Byung Jin Kim Hae Jin Kim Seonghoon Choi Jin Oh Na Young Youl Hyun Bum Joon Kim Kyung-Do Han In-Kyung Jeong Source Type: research

Cardiovascular Outcomes according to Comorbidities and Low-Density Lipoprotein Cholesterol in Korean People with Type 2 Diabetes Mellitus
CONCLUSION: For primary prevention of CVD in Korean adults with T2DM, it can be helpful to lower LDL-C targets when there are chronic kidney disease, HT, a long duration of diabetes mellitus, or three or more CV risk factors.PMID:36727163 | DOI:10.4093/dmj.2021.0344
Source: Diabetes and Metabolism Journal - February 2, 2023 Category: Endocrinology Authors: Min Kyong Moon Junghyun Noh Eun-Jung Rhee Sang Hyun Park Hyeon Chang Kim Byung Jin Kim Hae Jin Kim Seonghoon Choi Jin Oh Na Young Youl Hyun Bum Joon Kim Kyung-Do Han In-Kyung Jeong Source Type: research

Association between Low-Density Lipoprotein Cholesterol Level and Cardiovascular Outcomes in Korean Adults: A Nationwide Cohort Study
CONCLUSION: We confirmed the incidence of CVD was increased in higher LDL-C range. The risk of CVD increased from ≥70 mg/dL of LDL-C in very high-risk and high-risk groups, and from ≥130 mg/dL of LDL-C in moderate-risk and low-risk groups in Korean adults.PMID:36727164 | DOI:10.4093/dmj.2021.0320
Source: Diabetes and Metabolism Journal - February 2, 2023 Category: Endocrinology Authors: Junghyun Noh Min Kyong Moon Eun-Jung Rhee Sang Hyun Park Hyeon Chang Kim Byung Jin Kim Hae Jin Kim Seonghoon Choi Jin Oh Na Young Youl Hyun Bum Joon Kim Kyung-Do Han In-Kyung Jeong Source Type: research

Cardiovascular Outcomes according to Comorbidities and Low-Density Lipoprotein Cholesterol in Korean People with Type 2 Diabetes Mellitus
CONCLUSION: For primary prevention of CVD in Korean adults with T2DM, it can be helpful to lower LDL-C targets when there are chronic kidney disease, HT, a long duration of diabetes mellitus, or three or more CV risk factors.PMID:36727163 | DOI:10.4093/dmj.2021.0344
Source: Diabetes and Metabolism Journal - February 2, 2023 Category: Endocrinology Authors: Min Kyong Moon Junghyun Noh Eun-Jung Rhee Sang Hyun Park Hyeon Chang Kim Byung Jin Kim Hae Jin Kim Seonghoon Choi Jin Oh Na Young Youl Hyun Bum Joon Kim Kyung-Do Han In-Kyung Jeong Source Type: research

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