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Diabetes mellitus related biomarker: the predictive role of growth-differentiation factor-15
Publication date: Available online 9 October 2015 Source:Diabetes & Metabolic Syndrome: Clinical Research & Reviews Author(s): Alexander E. Berezin Growth differentiation factor-15 (GDF-15) is a stress-responsive cytokine, which belongs to super family of the transforming growth factor beta. GDF-15 is widely presented in the various cells (macrophages, vascular smooth muscle cells, adipocytes, cardiomyocytes, endothelial cells, fibroblasts), tissues (adipose tissue, vessels, tissues of central and peripheral nervous system) and organs (heart, brain, liver, placenta) and it plays an important role in the ...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - October 10, 2015 Category: Endocrinology Source Type: research

Prevalence of Type 2 Diabetes Mellitus Complications among Palestinians with T2DM
Conclusions The present cross-sectional study shows poor glycemic control in Palestine, while blood pressure and lipids are less poorly controlled. The study emphasizes the need to optimize the glucose-lowering treatment and to implement diabetes care program that could face the challenge of high uncontrolled diabetes as well as complications of diabetes.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - June 3, 2017 Category: Endocrinology Source Type: research

Cardiovascular risk assessment in prediabetic patients in a hypertensive population: The role of cystatin C
Conclusions Prediabetes was associated with an increased risk of CV events, when compared with the non-prediabetic patients. Age and cystatin C were found as significant risk factors for CV events in the prediabetic cohort.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - April 10, 2018 Category: Endocrinology Source Type: research

Chronic kidney disease among US adults with type 2 diabetes and cardiovascular diseases: A national estimate of prevalence by KDIGO 2012 classification
ConclusionsThis study confirms the high prevalence of CKD in patients with multiple comorbidities: T2D and CVD. It also provides estimates of the prevalence of CKD categories based on KDIGO 2012 classification for US adults with T2D.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - November 3, 2018 Category: Endocrinology Source Type: research

Albuminuric and non-albuminuric patterns of chronic kidney disease in type 2 diabetes
Publication date: Available online 3 November 2018Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Vadim V. Klimontov, Anton I. KorbutAbstractA growing body of evidence supports a shift in the natural history of chronic kidney disease (CKD) in subjects with diabetes. Specifically, normoalbuminuric chronic kidney disease (NA-CKD), which is characterized by a decline in the glomerular filtration rate in the absence of a preceding or accompanying elevation of albuminuria, has become a widely prevalent variant of renal impairment in diabetes. Diabetic women and nonsmoking individuals with better gly...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - November 3, 2018 Category: Endocrinology Source Type: research

The morphofunctional features of platelets against the background of metabolic syndrome in patients with generalized marginal periodontitis
Conclusion: The presented data provide strong evidence for changes in the morphofunctional state of peripheral blood platelets in patients with generalized marginal periodontitis of mild and moderate degree against the background of metabolic syndrome.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - December 7, 2018 Category: Endocrinology Source Type: research