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Source: Atherosclerosis
Condition: Heart Attack
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Total 556 results found since Jan 2013.
Microfluidic-to-macrofluidic: A simple < em > in vitro < /em > model of atherosclerosis induced by fluidic stimulation
Biomicrofluidics. 2023 Aug 29;17(4):044106. doi: 10.1063/5.0155267. eCollection 2023 Jul.ABSTRACTAtherosclerosis is the narrowing of the arteries due to the formation of fatty plaques, which is the main cause of myocardial infarction and stroke. It is important to develop an in vitro model that can combine multiple-type cell co-culture, vessel wall-like structure, and fluid condition to simulate the processes of atherosclerosis. Herein, we used a simple microfluidic chip made of three polydimethylsiloxane layers to co-culture endothelial and smooth muscle cells in a flat rectangular microchannel. After being connected with...
Source: Atherosclerosis - September 4, 2023 Category: Cardiology Authors: Jingang Cui Wei Jiang Jilei Su Jiazhen Zhang Yongliang Yu Yongsheng Ding Source Type: research
Causal associations between type 1 diabetes mellitus and cardiovascular diseases: a Mendelian randomization study
CONCLUSION: This MR study provided evidence supporting the causal effect of T1DM on peripheral atherosclerosis and coronary atherosclerosis, with hypertension partly mediating this effect.PMID:37659996 | PMC:PMC10475187 | DOI:10.1186/s12933-023-01974-6
Source: Atherosclerosis - September 2, 2023 Category: Cardiology Authors: Zirui Liu Haocheng Wang Zhengkai Yang Yu Lu Cao Zou Source Type: research
Carotid total plaque area as an independent predictor of short-term subclinical polyvascular atherosclerosis progression and major adverse cardiac and cerebrovascular events
CONCLUSION: In patients from 40 to 64 years of age with various cardiovascular risks, among the indicators of the cPB, only an increase in cTPA > 42.0 mm2 was shown to be independently associated with an increase in the relative risk (RR) of progression of subclinical polyvascular atherosclerosis by 2.38 (1.08-5.25) times, as well as with the development of MACCE by 3.10 (1.54-6.26) times.PMID:37655749 | DOI:10.1177/17539447231194861
Source: Atherosclerosis - September 1, 2023 Category: Cardiology Authors: Vadim Genkel Alla Kuznetsova Evgeniy Lebedev Alexey Salashenko Albina Savochkina Karina Nikushkina Lubov Pykhova Veronika Sumerkina Igor Shaposhnik Source Type: research
Cardiovascular events risk in patients with systemic autoimmune diseases: a prognostic systematic review and meta-analysis
CONCLUSION: Patients with SAD present an increased risk of CV morbidity and mortality, which should be considered when establishing therapeutic strategies. These findings support the role of systemic inflammation in the development of atherosclerosis-driven disease.PMID:37650912 | DOI:10.1007/s00392-023-02291-4
Source: Atherosclerosis - August 31, 2023 Category: Cardiology Authors: Claudia Asenjo-Lobos Leticia Gonz ález Juan Francisco Bulnes Marta Roque Paula Mu ñoz Venturelli Gonzalo Mart ínez Rodríguez Source Type: research
Evaluating Preoperative Intravenous Iron and Erythropoietin Treatment and Outcomes in Cardiac Surgery Patients
CONCLUSIONS: Infection (P = 0.258), mortality rate (P = 0.440), and RBC utilization (P = 0.469) in the two groups of injection and non-injection were not significantly different.PMID:37645003 | PMC:PMC10461381 | DOI:10.5812/aapm-130899
Source: Atherosclerosis - August 30, 2023 Category: Cardiology Authors: Alireza Jahangirifard Azita Chegini Amirhossein Maghari Source Type: research
Screening and Management of Coronary Artery Disease in Kidney Transplant Candidates
Diagnostics (Basel). 2023 Aug 20;13(16):2709. doi: 10.3390/diagnostics13162709.ABSTRACTCardiovascular disease (CVD) is a major cause of morbidity and mortality in patients with chronic kidney disease (CKD), especially in end-stage renal disease (ESRD) patients and during the first year after transplantation. For these reasons, and due to the shortage of organs available for transplant, it is of utmost importance to identify patients with a good life expectancy after transplant and minimize the transplant peri-operative risk. Various conditions, such as severe pulmonary diseases, recent myocardial infarction or stroke, and ...
Source: Atherosclerosis - August 26, 2023 Category: Cardiology Authors: Giuseppe Vadal à Chiara Alaimo Giancarlo Buccheri Luca Di Fazio Leandro Di Caccamo Vincenzo Sucato Manlio Cipriani Alfredo Ruggero Galassi Source Type: research
Angiotensin Receptor-Neprilysin Inhibitor Effects on Atherosclerotic Cardiovascular Disease Events: A Meta-Analysis of Randomized Controlled Trials
In conclusion, this meta-analysis found no association between ARNI therapy and improved ASCVD events in patients with HF.PMID:37619492 | DOI:10.1016/j.amjcard.2023.07.154
Source: Atherosclerosis - August 24, 2023 Category: Cardiology Authors: Lis Victoria Ravani Douglas Mesadri Gewehr Pedro Calomeni Mateus de Miranda Gauza Jussara Pereira Rhanderson Cardoso Henrique Barbosa Ribeiro Edimar Bocchi Source Type: research
Carotid Plaque Score for Stroke and Cardiovascular Risk Prediction in a Middle-Aged Cohort From the General Population
Conclusions The carotid plaque score is a strong predictor of ischemic stroke and major adverse cardiovascular events, and it provides incremental prognostic information to SCORE2 for risk prediction. A cutoff score of >3 seems to be suitable to discriminate high-risk subjects. Registration Information clinicaltrials.gov. Identifier: NCT01555411.PMID:37609981 | DOI:10.1161/JAHA.123.030739
Source: Atherosclerosis - August 23, 2023 Category: Cardiology Authors: H åkon Ihle-Hansen Thea Vigen Trygve Berge Marte M Walle-Hansen Guri Hagberg Hege Ihle-Hansen Bente Thommessen Inger Ariansen Helge R øsjø Ole Morten R ønning Arnljot Tveit Magnus Lyngbakken Source Type: research
Evaluation of Large-Scale Proteomics for Prediction of Cardiovascular Events
CONCLUSIONS AND RELEVANCE: A protein risk score was significantly associated with ASCVD events in primary and secondary event populations. When added to clinical risk factors, the protein risk score and polygenic risk score both provided statistically significant but modest improvement in discrimination.PMID:37606673 | DOI:10.1001/jama.2023.13258
Source: Atherosclerosis - August 22, 2023 Category: Cardiology Authors: Hannes Helgason Thjodbjorg Eiriksdottir Magnus O Ulfarsson Abhishek Choudhary Sigrun H Lund Erna V Ivarsdottir Grimur Hjorleifsson Eldjarn Gudmundur Einarsson Egil Ferkingstad Kristjan H S Moore Narimon Honarpour Thomas Liu Huei Wang Thomas Hucko Marc S S Source Type: research
Effect of Beta-Blocker on Long-Term Major Cardiovascular Events in High Atherosclerotic Risk Population
CONCLUSION: In patients with high atherosclerotic cardiovascular risk, taking beta-blockers had a higher risk of 3P-MACEs. Care should be taken when prescribing beta-blockers to patients without a clear indication.TRIAL REGISTRATION: TCTR20130520001 registered in Thai Clinical Trials Registry (TCTR) https://www.thaiclinicaltrials.org/ , date of registration 20 May 2013.PMID:37594650 | DOI:10.1007/s10557-023-07502-8
Source: Atherosclerosis - August 18, 2023 Category: Cardiology Authors: Nichanan Osataphan Kamol Udol Khanchai Siriwattana Bancha Sukanandachai Siriluck Gunaparn Wachiranun Sirikul Arintaya Phrommintikul Wanwarang Wongcharoen Source Type: research
The role of macrophage ion channels in the progression of atherosclerosis
Front Immunol. 2023 Jul 31;14:1225178. doi: 10.3389/fimmu.2023.1225178. eCollection 2023.ABSTRACTAtherosclerosis is a complex inflammatory disease that affects the arteries and can lead to severe complications such as heart attack and stroke. Macrophages, a type of immune cell, play a crucial role in atherosclerosis initiation and progression. Emerging studies revealed that ion channels regulate macrophage activation, polarization, phagocytosis, and cytokine secretion. Moreover, macrophage ion channel dysfunction is implicated in macrophage-derived foam cell formation and atherogenesis. In this context, exploring the regul...
Source: Atherosclerosis - August 17, 2023 Category: Cardiology Authors: Xin Wu Sidhant Singla Jianhua J Liu Liang Hong Source Type: research
Atherosclerosis Burden of Brain- and Heart-Supplying Arteries and the Relationship With Vascular Risk in Patients With Ischemic Stroke
Conclusions The single-territory AB of intracranial, cervical, aortic, or coronary arteries might be not reliable for vascular risk stratification in patients with ischemic stroke, and evaluating the TAB of BHAs by quantitatively integrating the single-territory AB is advisable.PMID:37581397 | DOI:10.1161/JAHA.123.029505
Source: Atherosclerosis - August 15, 2023 Category: Cardiology Authors: Qi Kong Xin Ma Luguang Li Chen Wang Xiangying Du Yungao Wan Source Type: research
