• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Anti ‐Inflammatory Therapy for Atherosclerosis:Interpreting Divergent Results from the CANTOS and CIRT Clinical Trials
This article is protected by copyright. All rights reserved.
Source: Journal of Internal Medicine - November 25, 2018 Category: Internal Medicine Authors: Paul M Ridker Tags: Commentary Source Type: research

Morbidity and cause ‐specific mortality in first‐time myocardial infarction with nonobstructive coronary arteries
ConclusionsPatients with first ‐time MINOCA have a considerable risk of adverse events. This stresses the need for a comprehensive search of the cause of MINOCA, thorough treatment of underlying disease triggers and close follow‐up.
Source: Journal of Internal Medicine - November 25, 2018 Category: Internal Medicine Authors: K. M. Eggers, M. Hjort, T. Baron, T. Jernberg, A. M. Nordenskj öld, P. Tornvall, B. Lindahl Tags: Original Article Source Type: research

Long ‐term use of proton pump inhibitors, dose–response relationship and associated risk of ischemic stroke and myocardial infarction
ConclusionUse of PPIs was associated with increased risks of first‐time ischemic stroke and MI, particularly amongst long‐term users and at high doses.
Source: Journal of Internal Medicine - November 7, 2017 Category: Internal Medicine Authors: T. S. G. Sehested, T. A. Gerds, E. L. Fosb øl, P. W. Hansen, M. G. Charlot, N. Carlson, M. A. Hlatky, C. Torp‐Pedersen, G. H. Gislason Tags: Original Article Source Type: research

Proton ‐Pump Inhibitor Use and the Risk of First‐Time Ischemic Stroke in the General Population
This article is protected by copyright. All rights reserved.
Source: Journal of Internal Medicine - October 28, 2017 Category: Internal Medicine Authors: Cong Dai, Min Jiang, Qin Cao Tags: Letter to the Editor Source Type: research

Long ‐term use of Proton Pump Inhibitors, Dose‐response Relationship, and Associated Risk of Ischemic Stroke and Myocardial Infarction
ConclusionUse of PPIs was associated with increased risks of first‐time ischemic stroke and MI, particularly among long‐term users and at high doses.This article is protected by copyright. All rights reserved.
Source: Journal of Internal Medicine - October 1, 2017 Category: Internal Medicine Authors: Thomas S. G. Sehested, Thomas A. Gerds, Emil L. Fosb øl, Peter W. Hansen, Mette G. Charlot, Nicholas Carlson, Mark A. Hlatky, Christian Torp‐Pedersen, Gunnar H. Gislason Tags: Original Source Type: research

Important factors affecting the choice of an oral anticoagulant may be missed in database studies
This article is protected by copyright. All rights reserved.
Source: Journal of Internal Medicine - September 7, 2017 Category: Internal Medicine Authors: Emma Aarnio, Risto Huupponen, Maarit Jaana Korhonen Tags: Letter to the Editor Source Type: research

Plasma stem cell factor levels are associated with risk of cardiovascular disease and death
ConclusionsThis prospective population‐based study demonstrates that subjects with high levels of SCF have a lower risk of cardiovascular events and death. The findings provide clinical support for a protective role of SCF in maintaining cardiovascular integrity.This article is protected by copyright. All rights reserved.
Source: Journal of Internal Medicine - August 26, 2017 Category: Internal Medicine Authors: Harry Bj örkbacka, Ingrid Yao Mattisson, Maria Wigren, Olle Melander, Gunilla Nordin Fredrikson, Eva Bengtsson, Isabel Gonçalves, Peter Almgren, Jens O. Lagerstedt, Marju Orho‐Melander, Gunnar Engström, Jan Nilsson Tags: Original Source Type: research

Initiation of anticoagulation in atrial fibrillation: which factors are associated with choice of anticoagulant?
ConclusionsAF patients who were initiated on apixaban had higher stroke risk scores than patients initiated on VKAs. Interestingly, opposite results were found for dabigatranThis article is protected by copyright. All rights reserved.
Source: Journal of Internal Medicine - May 8, 2017 Category: Internal Medicine Authors: Anna Gundlund, Laila Staerk, Emil Loldrup Fosb øl, Kasper Gadsboel, Caroline Sindet‐Pedersen, Anders Nissen Bonde, Gunnar H. Gislason, Jonas Bjerring Olesen Tags: Original Source Type: research

Role of exosomes and microvesicles in hypoxia‐associated tumour development and cardiovascular disease
Abstract Exosomes and microvesicles, collectively referred to as extracellular vesicles (EVs), can transfer complex biological information and induce a diverse signalling response in recipient cells with potential relevance in a wide array of pathological conditions. Tissue hypoxia constitutes a stress‐associated phenotype that is central to the malignant state of aggressive tumours as well as to ischaemic tissue in cardiovascular disorders. The adaptive response to hypoxic stress is largely dependent on intercellular communication in which EVs, and cellular exchange of EV cargo molecules, have recently been implicated. ...
Source: Journal of Internal Medicine - July 8, 2015 Category: Internal Medicine Authors: M. Belting, H. C. Christianson Tags: Review Source Type: research

Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross‐sectional study
ConclusionsMeasures of atherosclerotic burden are associated with clinically manifest CVD in subjects with T2D. In addition, vascular changes that are not directly related to known metabolic risk factors are important in the development of both atherosclerosis and CVD in T2D. A better understanding of the mechanisms involved is crucial for enabling better identification of CVD risk in T2D.This article is protected by copyright. All rights reserved.
Source: Journal of Internal Medicine - March 9, 2015 Category: Internal Medicine Authors: Angela C. Shore, Helen M. Colhoun, Andrea Natali, Carlo Palombo, Gerd Östling, Kunihiko Aizawa, Cecilia Kennbäck, Francesco Casanova, Margaretha Persson, Kim Gooding, Phillip E. Gates, Faisel Kahn, Helen C. Looker, Fiona Adams, Jill Belch, Silvia Pinnol Tags: Original Article Source Type: research

Cardiovascular risk in patients with sleep apnoea with or without continuous positive airway pressure therapy: follow‐up of 4.5 million Danish adults
ConclusionsSleep apnoea is associated with increased risk of ischaemic stroke and MI, particularly in patients younger than 50 years of age. CPAP therapy was not associated with a reduced rate of stroke or MI.
Source: Journal of Internal Medicine - September 17, 2014 Category: Internal Medicine Authors: M. Lamberts, O. W. Nielsen, G. Y. H. Lip, M. H. Ruwald, C. B. Christiansen, S. L. Kristensen, C. Torp‐Pedersen, M. L. Hansen, G. H. Gislason Tags: Original Article Source Type: research

Cardiovascular risk in patients with sleep apnea with or without continuous positive airway pressure therapy: follow‐up of 4.5 million Danish adults
ConclusionsSleep apnoea is associated with increased risk of ischaemic stroke and MI, particularly in patients younger than 50 years of age. CPAP therapy was not associated with a reduced rate of stroke or MI.This article is protected by copyright. All rights reserved.
Source: Journal of Internal Medicine - August 28, 2014 Category: Internal Medicine Authors: M. Lamberts, O. W. Nielsen, G. Y. H. Lip, M. H. Ruwald, C. B. Christiansen, S. L. Kristensen, C. Torp‐Pedersen, M. L. Hansen, G. H. Gislason Tags: Original Source Type: research

The emerging role of microRNAs in cardiovascular disease
This article is protected by copyright. All rights reserved.
Source: Journal of Internal Medicine - August 27, 2014 Category: Internal Medicine Authors: Lars Maegdefessel Tags: Review Source Type: research

Soluble urokinase plasminogen activator receptor levels are elevated and associated with complications in patients with type 1 diabetes
ConclusionThe suPAR level is higher in patients with type 1 diabetes, and is associated with diabetes duration and complications independent of other risk factors. suPAR is a potential novel risk marker for the management of diabetes.This article is protected by copyright. All rights reserved.
Source: Journal of Internal Medicine - May 15, 2014 Category: Internal Medicine Authors: Simone Theilade, Stig Lyngbæk, Tine W. Hansen, Jesper Eugen‐Olsen, Mogens Fenger, Peter Rossing, Jørgen L. Jeppesen Tags: Original Source Type: research

The collagen cross‐linking enzyme lysyl oxidase is associated with the healing of human atherosclerotic lesions
ConclusionsLOX may contribute to the healing of atherosclerotic lesions and to prevention of its lethal complications. Mediators of inflammation may control LOX expression in plaques and hence plaque stability.This article is protected by copyright. All rights reserved.
Source: Journal of Internal Medicine - February 1, 2014 Category: Internal Medicine Authors: Olga A. Ovchinnikova, Lasse Folkersen, Jonas Persson, Jan H. N. Lindeman, Thor Ueland, Pål Aukrust, Natalya Gavrisheva, Eugene Shlyakhto, Gabrielle Paulsson‐Berne, Ulf Hedin, Peder S. Olofsson, Göran K. Hansson Tags: Original Source Type: research

Pages: 1  2