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Effectiveness and Safety of Dabigatran and Warfarin in Real-World US Patients With Non-Valvular Atrial Fibrillation: A Retrospective Cohort Study Health Services and Outcomes Research
Conclusions Dabigatran could be a safe and potentially more effective alternative to warfarin in patients with atrial fibrillation managed in routine practice settings.
Source: JAHA:Journal of the American Heart Association - April 10, 2015 Category: Cardiology Authors: Lauffenburger, J. C., Farley, J. F., Gehi, A. K., Rhoney, D. H., Brookhart, M. A., Fang, G. Tags: Health Services and Outcomes Research Source Type: research

Ideal Cardiovascular Health Predicts Functional Status Independently of Vascular Events: The Northern Manhattan Study Epidemiology
Conclusions Ideal CVH predicts functional status, even after accounting for incident vascular events. Vascular functional impairment is an important outcome that can be reduced by optimizing vascular health.
Source: JAHA:Journal of the American Heart Association - February 12, 2015 Category: Cardiology Authors: Dhamoon, M. S., Dong, C., Elkind, M. S. V., Sacco, R. L. Tags: Epidemiology Source Type: research

Lower Mortality Rate in Elderly Patients With Community-Onset Pneumonia on Treatment With Aspirin Epidemiology
Conclusions This study shows that chronic aspirin use is associated with lower mortality rate within 30 days after hospital admission in a large cohort of patients with pneumonia.
Source: JAHA:Journal of the American Heart Association - January 6, 2015 Category: Cardiology Authors: Falcone, M., Russo, A., Cangemi, R., Farcomeni, A., Calvieri, C., Barilla, F., Scarpellini, M. G., Bertazzoni, G., Palange, P., Taliani, G., Venditti, M., Violi, F. Tags: Epidemiology Source Type: research

The Effect of Hurricane Sandy on Cardiovascular Events in New Jersey Epidemiology
Conclusion In the 2 weeks following Hurricane Sandy, there were increases in the incidence of, and 30-day mortality from, MI and in the incidence of stroke.
Source: JAHA:Journal of the American Heart Association - December 8, 2014 Category: Cardiology Authors: Swerdel, J. N., Janevic, T. M., Cosgrove, N. M., Kostis, J. B., the Myocardial Infarction Data Acquisition System (MIDAS 24) Study Group Tags: Epidemiology Source Type: research

Prognostic Value of Estimated Functional Capacity Incremental to Cardiac Biomarkers in Stable Cardiac Patients Coronary Heart Disease
Conclusion A simple self-assessment tool of functional capacity in stable patients undergoing elective diagnostic cardiac evaluation provides independent and incremental prognostic value for prediction of both significant coronary angiographic disease and long-term adverse clinical events.
Source: JAHA:Journal of the American Heart Association - October 20, 2014 Category: Cardiology Authors: Tang, W. H. W., Topol, E. J., Fan, Y., Wu, Y., Cho, L., Stevenson, C., Ellis, S. G., Hazen, S. L. Tags: Coronary Heart Disease Source Type: research

HIV Infection and Cardiovascular Disease in Women Epidemiology
Conclusions HIV is associated with an increased risk of CVD in women.
Source: JAHA:Journal of the American Heart Association - October 16, 2014 Category: Cardiology Authors: Womack, J. A., Chang, C.-C. H., So-Armah, K. A., Alcorn, C., Baker, J. V., Brown, S. T., Budoff, M., Butt, A. A., Gibert, C., Goetz, M. B., Gottdiener, J., Gottlieb, S., Justice, A. C., Leaf, D., McGinnis, K., Rimland, D., Rodriguez-Barradas, M. C., Sico, Tags: Epidemiology Source Type: research

A Novel Protein Glycan Biomarker and Future Cardiovascular Disease Events Epidemiology
Conclusions In this prospective study of initially healthy women, baseline GlycA was associated with incident CVD, consistent with a possible role for protein glycans in inflammation and CVD. Clinical Trial Registration URL: http//clinicaltrials.gov/. Unique identifier NCT00000479.
Source: JAHA:Journal of the American Heart Association - September 23, 2014 Category: Cardiology Authors: Akinkuolie, A. O., Buring, J. E., Ridker, P. M., Mora, S. Tags: Epidemiology Source Type: research

Population Attributable Risks of Hypertension and Diabetes for Cardiovascular Disease and Stroke in the Northern Manhattan Study Epidemiology
Conclusions HTN and diabetes have important effects on the burden of stroke, particularly among those younger than age 80 and Hispanics. Public health campaigns targeted at specific risk factors in specific populations can lead to a greater reduction in CVD.
Source: JAHA:Journal of the American Heart Association - September 16, 2014 Category: Cardiology Authors: Willey, J. Z., Moon, Y. P., Kahn, E., Rodriguez, C. J., Rundek, T., Cheung, K., Sacco, R. L., Elkind, M. S. V. Tags: Epidemiology Source Type: research

Prognostic Implications of Left Ventricular Dyssynchrony for Major Adverse Cardiovascular Events in Asymptomatic Women and Men: The Multi-Ethnic Study of Atherosclerosis Heart Failure
Conclusions In an asymptomatic cohort, greater LV dyssynchrony determined by cardiac magnetic resonance imaging predicts adverse cardiovascular outcome in women but not in men. Clinical Trial Registration URL: http://clinicaltrials.gov. Unique identifier: NCT00005487.
Source: JAHA:Journal of the American Heart Association - August 4, 2014 Category: Cardiology Authors: Sharma, R. K., Volpe, G., Rosen, B. D., Ambale-Venkatesh, B., Donekal, S., Fernandes, V., Wu, C. O., Carr, J., Bluemke, D. A., Lima, J. A. C. Tags: Heart Failure Source Type: research

B-type Natriuretic Peptides for the Prediction of Cardiovascular Events in Patients With Stable Coronary Heart Disease: The Heart and Soul Study Coronary Heart Disease
Conclusions Both BNP and NT-proBNP were significant predictors of MACE in stable coronary heart disease; however, NT-proBNP was superior to BNP for net risk reclassification for MACE.
Source: JAHA:Journal of the American Heart Association - July 22, 2014 Category: Cardiology Authors: Mishra, R. K., Beatty, A. L., Jaganath, R., Regan, M., Wu, A. H. B., Whooley, M. A. Tags: Coronary Heart Disease Source Type: research

Socioeconomic Position and Incidence of Ischemic Stroke in Denmark 2003-2012. A Nationwide Hospital-Based Study Stroke
Conclusions In Denmark, there is a strong relation between low socioeconomic position and risk for hospitalization for stroke. Lifestyle, as indicated by smoking, obesity, and alcohol consumption, and diabetes appears to increase the risk for stroke in people with lower socioeconomic position.
Source: JAHA:Journal of the American Heart Association - July 16, 2014 Category: Cardiology Authors: Andersen, K. K., Steding-Jessen, M., Dalton, S. O., Olsen, T. S. Tags: Stroke Source Type: research

Plasma Levels of the Proinflammatory Chitin-Binding Glycoprotein YKL-40, Variation in the Chitinase 3-Like 1 Gene (CHI3L1), and Incident Cardiovascular Events Epidemiology
Conclusions Among initially healthy U.S. women, plasma levels of the proinflammatory chitenase-like protein, YKL-40, were influenced by environmental as well as genetic factors and predicted incident thromboembolic stroke, but not MI, a differential effect consistent with limited previous data.
Source: JAHA:Journal of the American Heart Association - June 23, 2014 Category: Cardiology Authors: Ridker, P. M., Chasman, D. I., Rose, L., Loscalzo, J., Elias, J. A. Tags: Epidemiology Source Type: research

Haptoglobin 2-2 Genotype is Not Associated With Cardiovascular Risk in Subjects With Elevated Glycohemoglobin--Results From the Bruneck Study Genetics
Conclusions Subjects with the Hp 2-2 genotype and elevated HbA1c compared with subjects with other Hp genotypes and elevated HbA1c did not show increased CVD risk.
Source: JAHA:Journal of the American Heart Association - May 16, 2014 Category: Cardiology Authors: Pechlaner, R., Kiechl, S., Willeit, P., Demetz, E., Haun, M., Weger, S., Oberhollenzer, F., Kronenberg, F., Bonora, E., Weiss, G., Willeit, J. Tags: Genetics Source Type: research

Cardiovascular and Mortality Risk of Apparent Resistant Hypertension in Women With Suspected Myocardial Ischemia: A Report From the NHLBI-Sponsored WISE Study Hypertension
Conclusions In this cohort of women with evidence of ischemia, aTRH was associated with a profoundly increased long-term risk of major adverse events, including death, that emerged early during follow-up.
Source: JAHA:Journal of the American Heart Association - February 28, 2014 Category: Cardiology Authors: Smith, S. M., Huo, T., Delia Johnson, B., Bittner, V., Kelsey, S. F., Vido Thompson, D., Noel Bairey Merz, C., Pepine, C. J., Cooper-DeHoff, R. M. Tags: Hypertension Source Type: research

New-Onset Atrial Fibrillation is Associated With Cardiovascular Events Leading to Death in a First Time Myocardial Infarction Population of 89 703 Patients With Long-Term Follow-Up: A Nationwide Study Coronary Heart Disease
Conclusions New-onset AF after first-time MI is associated with increased mortality, which is largely explained by more cardiovascular deaths. Focus on the prognostic impact of post-infarct AF is warranted.
Source: JAHA:Journal of the American Heart Association - January 21, 2014 Category: Cardiology Authors: Bang, C. N., Gislason, G. H., Greve, A. M., Bang, C. A., Lilja, A., Torp-Pedersen, C., Andersen, P. K., Kober, L., Devereux, R. B., Wachtell, K. Tags: Coronary Heart Disease Source Type: research

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