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Source: Neuroscience
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Drug: Neurontin

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Gabapentin prevents cortical spreading depolarization-induced disinhibition
Publication date: 11 October 2017 Source:Neuroscience, Volume 361 Author(s): Masoud Mesgari, Johanna Krüger, Christopher Theo Riemer, Maryam Khaleghi Ghadiri, Stjepana Kovac, Ali Gorji Cortical spreading depolarization (CSD) has an important role in brain diseases such as stroke, subarachnoid hemorrhage, migraine with aura, and epilepsy. Several anti-epileptic drugs (AEDs) are used to treat paroxysmal brain diseases and are thus known to suppress CSD. One of these AEDs is gabapentin (GBP) which has been traditionally used for treatment of some CSD-related neurological diseases. We applied intra- and extracellular recordi...
Source: Neuroscience - September 2, 2017 Category: Neuroscience Source Type: research