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New spectrum of the neurologic consequences of Zika
Zika virus infection represents a new neuropathological agent with association to a wide spectrum of neurological complications: a) Congenital Zika Syndrome by affecting the neural stem cells of the human fetal brain; b) Guillain-Barr é Syndrome by an autoimmune response against peripheral myelin and/or axonal components or probable direct inflammatory reaction; c) Encephalitis/meningoencephalitis and myelitis by a direct viral inflammatory process on the central nervous system; d) Sensory neuropathy by infecting directly the pe ripheral neurons and causing substantial cell death and pathogenic transcriptional dysregulati...
Source: Journal of the Neurological Sciences - October 31, 2017 Category: Neurology Authors: Marco T. Medina, Marco Medina-Montoya Tags: Editorial Source Type: research

ZIKA vasculitis: A new cause of stroke in children?
Viral infectious vasculitis is a cause of stroke in children. Zika virus infection is often asymptomatic. Neurological complications have however been reported: Guillain-Barr é, ADEM, meningoencephalitis, myelitis, microcephaly in the fetus of infected mothers. We discuss the case of a child presenting acute infection with ZIKV that was associated with a stroke. A 10-months-old boy without medical history presented after 2days of fever and cutaneous rash, conjunctivitis on day 5, a right hemiparesis on day 6.
Source: Journal of the Neurological Sciences - October 27, 2017 Category: Neurology Authors: Anne Landais, Audrey C ésaire, Manuel Fernandez, Sébastien Breurec, Cécile Herrmann, Fréderique Delion, Philippe Desprez Tags: Letter to the Editor Source Type: research