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The efficacy of selective transcranial magnetic stimulation with functional near-infrared spectroscopy and intensive speech therapy on individuals with post-stroke aphasia
Introduction: To examine the efficacy of selective repetitive transcranial magnetic stimulation (rTMS) therapy guided by functional near-infrared spectroscopy (fNIRS) combined with intensive speech therapy(ST) on post-stroke patients with aphasia, and right hemisphere high-frequency rTMS combined with intensive ST on patients who were right hemisphere-activated in a language task.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: T. Hara, M. Abo, K. Kakita Source Type: research

Sequential Theta burst stimulation changes language function after stroke - Preliminary analysis in Chinese survivors
Introduction: Theta burst stimulation (TBS) is a patterned repetitive transcranial magnetic stimulation (rTMS) protocol with relatively short stimulation period and strong power. Controlled trial of sequential TBS in post-stroke aphasia has been scarce. We aimed to investigate the potential therapeutic effect of consecutive suppressive-facilitatory TBS on language outcome after stroke.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: W. He, K. Lee, T. Leung, H. Leung, Q. Zhang, L. Wong Source Type: research

Transcranial Direct Current Stimulation and neural reorganisation after aphasia treatment
This study aims to investigate the effect of LH anodal tDCS on the neural reorganisation of language in the context of aphasia treatment.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: R.M.A. Blom-Smink, K. Spielmann, C.P.M. Orellana, M. Smits, J. Crinion, W.M.E. van de Sandt-Koenderman, G.M. Ribbers Source Type: research

Effects of rTMS based on brain activation during language performance in stroke patients with non-fluent Aphasia (Pilot Study)
Introduction: In post-stroke aphasia rehabilitation, repetitive transcranial stimulation (rTMS) aimed to reinforce the activity of the brain regions in the left hemisphere. Most conventional rTMS studies employed an inhibitory low frequency protocol for the contralesional homologs of Broca's area. In the present pilot study, we performed functional near-infrared spectroscopy (fNIRS) prior to excitatory rTMS treatment for selection of the most appropriate application of stimulation. The purpose of this study is to assess the safety and clinical efficacy of high frequency repetitive transcranial magnetic stimulation based on...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: B.S. Kwon, N.-J. Paik, W.-S. Kim, J.-H. Park, S. Kwon Source Type: research

Effects of prefrontal transcranial direct current stimulation on language production in post-stroke aphasia
A successful interplay between prefrontal and domain-specific language areas has been shown to be crucial for language processing. Non-invasive brain stimulation is increasingly being used as a promising therapeutic tool for neurological diseases. The aim of the present study is to investigate the effects of transcranial direct current stimulation (tDCS) of the prefrontal cortex (PFC) on language production in chronic post-stroke aphasic patients.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: M.I. Pestalozzi, M. Di Pietro, G. Gaytanidis, L. Chouiter, L. Spierer, A. Schnider, J.M. Annoni, L.B. Jost Source Type: research

Considerations for Research Treatment of Aphasia Combining Neuromodulation and Speech-Language Intervention
Aphasia, commonly defined as impairment or loss of language functions, is a frequent and often chronic consequence of left-hemispheric stroke. The effects of aphasia on patient independence and quality of life are often lifelong. Although beneficial in some cases, the effectiveness of behavioral speech-language therapy is often limited. Therefore, in these last decades, new treatment designs combining speech-language therapy and noninvasive brain stimulation techniques such as transcranial direct current stimulation (tDCS) have been developed with the goal of maximizing the recovery process.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - December 31, 2016 Category: Neurology Authors: Elizabeth E. Galletta, Adam Buchwald, Jessica Richardson, Julius Fridriksson, Roy Hamilton, Peter Turkeltaub, Paola Marangolo Source Type: research

Use of computational modeling to inform tDCS electrode montages for the promotion of language recovery in post-stroke aphasia
Although pilot trials of transcranial direct current stimulation (tDCS) in aphasia are encouraging, protocol optimization is needed. Notably, it has not yet been clarified which of the varied electrode montages investigated is the most effective in enhancing language recovery.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - July 2, 2015 Category: Neurology Authors: Elizabeth E. Galletta, Andrea Cancelli, Carlo Cottone, Ilaria Simonelli, Franca Tecchio, Marom Bikson, Paola Marangolo Source Type: research

Broca's Area Damage is Necessary but not Sufficient to Induce After-effects of cathodal tDCS on the Unaffected Hemisphere in Post-stroke Aphasia
The inter-individual variability of behavioral effects after tDCS applied to the unaffected right hemisphere in stroke may be related to factors such as the lesion location.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 13, 2014 Category: Neurology Authors: C. Rosso, V. Perlbarg, R. Valabregue, C. Arbizu, S. Ferrieux, B. Alshawan, P. Vargas, A. Leger, C. Zavanone, J.C. Corvol, S. Meunier, S. Lehéricy, Y. Samson Tags: Transcranial Direct Current Stimulation (tDCS)/Transcranial Alternating Current Stimulation (tACS) Source Type: research

Can enhancing left lateralization using transcranial direct current stimulation improve recovery from post-stroke aphasia?
One third of stroke victims suffer from aphasia, an acquired language disorder for which there are few effective medical treatments. Aphasia often does not resolve completely, resulting in substantial long-term disability. After a stroke that causes aphasia, the reorganization of language networks in the brain involves compensatory recruitment of brain tissue in the left hemisphere as well as potentially maladaptive recruitment of symmetric areas in the right hemisphere. One avenue for intervention might be to externally “left lateralize” the brain, enhancing activity of the left frontal lobe while inhibiting the right...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 1, 2014 Category: Neurology Authors: Mackenzie Fama, Elizabeth Lacey, Alexa Desko, Lauren Taylor, Laura Hussey, Peter Turkeltaub Tags: Abstracts Presented at NYC Neuromodulation 2013 Source Type: research

Talking and tDCS Treatment for Stroke Survivors with Aphasia
This pilot study involves the use of transcranial direct current stimulation (tDCS), in conjunction with speech-language therapy for aphasia. In recent years, researchers have investigated the use of noninvasive brain stimulation techniques such as TMS (transcranial magnetic stimulation) and tDCS for the modulation of brain activity to improve function post stroke. In contrast to TMS, administering speech-language therapy at the same time is feasible with tDCS since the environment is quiet. Although several studies include behavioral therapy, the specifics regarding the speech-language treatment have not been described, a...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 1, 2014 Category: Neurology Authors: Elizabeth Galletta, Amy Vogel, Steven Baumann Tags: Abstracts Presented at NYC Neuromodulation 2013 Source Type: research

HD-tDCS to enhance behavioral treatment for aphasia: A feasibility study
Transcranial direct current stimulation (tDCS) enhances treatment outcomes post-stroke. Effects depend largely on which cortical areas are targeted. Feasibility and tolerability of high-definition (HD) tDCS, a technique that is thought to increase current focality and intensity, for consecutive weekdays as an adjunct to behavioral treatment in a clinical population has not been demonstrated.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 1, 2014 Category: Neurology Authors: Jessica D. Richardson, Abhishek Datta, Jacek Dmochowski, Lucas Parra, Julius Fridriksson Tags: Abstracts Presented at NYC Neuromodulation 2013 Source Type: research

Treatment of severe expressive dysphasia with rTMS and language therapy after childhood stroke.
Childhood stroke causes lifelong language disability. Expressive dysphasia accompanies left inferior frontal gyrus (IFG/Broca) injury. Recovery and therapy effects may relate to interhemispheric balance with homologous, contralesional IFG. Inhibiting contralesional IFG with repetitive transcranial magnetic stimulation (rTMS) may improve adult stroke dysphasia but is unexplored in children.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 1, 2014 Category: Neurology Authors: Helen L. Carlson, Aleksandra Mineyko, Omar Damji, Zeanna Zadavji, Rebecca Patzelt, Anya Mazur-Mosiewicz, Adam Kirton Tags: Abstracts Presented at NYC Neuromodulation 2013 Source Type: research

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