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Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation
Condition: Aphasia

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Total 28 results found since Jan 2013.

Can enhancing left lateralization using transcranial direct current stimulation improve recovery from post-stroke aphasia?
One third of stroke victims suffer from aphasia, an acquired language disorder for which there are few effective medical treatments. Aphasia often does not resolve completely, resulting in substantial long-term disability. After a stroke that causes aphasia, the reorganization of language networks in the brain involves compensatory recruitment of brain tissue in the left hemisphere as well as potentially maladaptive recruitment of symmetric areas in the right hemisphere. One avenue for intervention might be to externally “left lateralize” the brain, enhancing activity of the left frontal lobe while inhibiting the right...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 1, 2014 Category: Neurology Authors: Mackenzie Fama, Elizabeth Lacey, Alexa Desko, Lauren Taylor, Laura Hussey, Peter Turkeltaub Tags: Abstracts Presented at NYC Neuromodulation 2013 Source Type: research

Treatment of severe expressive dysphasia with rTMS and language therapy after childhood stroke.
Childhood stroke causes lifelong language disability. Expressive dysphasia accompanies left inferior frontal gyrus (IFG/Broca) injury. Recovery and therapy effects may relate to interhemispheric balance with homologous, contralesional IFG. Inhibiting contralesional IFG with repetitive transcranial magnetic stimulation (rTMS) may improve adult stroke dysphasia but is unexplored in children.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 1, 2014 Category: Neurology Authors: Helen L. Carlson, Aleksandra Mineyko, Omar Damji, Zeanna Zadavji, Rebecca Patzelt, Anya Mazur-Mosiewicz, Adam Kirton Tags: Abstracts Presented at NYC Neuromodulation 2013 Source Type: research

Effects of rTMS based on brain activation during language performance in stroke patients with non-fluent Aphasia (Pilot Study)
Introduction: In post-stroke aphasia rehabilitation, repetitive transcranial stimulation (rTMS) aimed to reinforce the activity of the brain regions in the left hemisphere. Most conventional rTMS studies employed an inhibitory low frequency protocol for the contralesional homologs of Broca's area. In the present pilot study, we performed functional near-infrared spectroscopy (fNIRS) prior to excitatory rTMS treatment for selection of the most appropriate application of stimulation. The purpose of this study is to assess the safety and clinical efficacy of high frequency repetitive transcranial magnetic stimulation based on...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: B.S. Kwon, N.-J. Paik, W.-S. Kim, J.-H. Park, S. Kwon Source Type: research

Sequential Theta burst stimulation changes language function after stroke - Preliminary analysis in Chinese survivors
Introduction: Theta burst stimulation (TBS) is a patterned repetitive transcranial magnetic stimulation (rTMS) protocol with relatively short stimulation period and strong power. Controlled trial of sequential TBS in post-stroke aphasia has been scarce. We aimed to investigate the potential therapeutic effect of consecutive suppressive-facilitatory TBS on language outcome after stroke.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: W. He, K. Lee, T. Leung, H. Leung, Q. Zhang, L. Wong Source Type: research

Abstract #7: HD-tDCS to contralesional hemisphere to enhance treatment outcomes in persons with stroke-induced aphasia
Background: Chronic aphasia, or language difficulty persisting beyond one year post-stroke, affects over 2.5 million individuals in the United States. Treatment response varies and language abilities are rarely restored. Intact, connected ipsilesional language areas and improved interhemispheric balance following stroke are consistent predictors of recovery. A promising approach to target these brain dynamics is using high-definition transcranial direct current stimulation (HD-tDCS) to deliver focal cathodal current to right frontal areas in the contralesional hemisphere, combined with efficacious behavioral treatment that...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: J.D. Richardson, S.G.H. Dalton, J.F. Cavanagh, C. Shultz, J. Adams Source Type: research

Transcranial alternating current stimulation enhances speech comprehension in chronic post-stroke aphasia patients: A single-blind sham-controlled study
Aphasia is one of the most devastating complications following stroke [1]. Speech and language therapy (SLT) [2] is recommended for post-stroke aphasia (PSA), but the benefits remain limited. Several recent studies have examined the potential efficacy of combining SLT with various forms of non-invasive brain stimulation (NIBS), including transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS). While tDCS is accepted by clinicians and patients due to low cost and documented safety, it has not proven effective for improving speech comprehension [3].
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - December 6, 2022 Category: Neurology Authors: Xiaohui Xie, Panpan Hu, Yanghua Tian, Kai Wang, Tongjian Bai Source Type: research

Talking and tDCS Treatment for Stroke Survivors with Aphasia
This pilot study involves the use of transcranial direct current stimulation (tDCS), in conjunction with speech-language therapy for aphasia. In recent years, researchers have investigated the use of noninvasive brain stimulation techniques such as TMS (transcranial magnetic stimulation) and tDCS for the modulation of brain activity to improve function post stroke. In contrast to TMS, administering speech-language therapy at the same time is feasible with tDCS since the environment is quiet. Although several studies include behavioral therapy, the specifics regarding the speech-language treatment have not been described, a...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 1, 2014 Category: Neurology Authors: Elizabeth Galletta, Amy Vogel, Steven Baumann Tags: Abstracts Presented at NYC Neuromodulation 2013 Source Type: research

Broca's Area Damage is Necessary but not Sufficient to Induce After-effects of cathodal tDCS on the Unaffected Hemisphere in Post-stroke Aphasia
The inter-individual variability of behavioral effects after tDCS applied to the unaffected right hemisphere in stroke may be related to factors such as the lesion location.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 13, 2014 Category: Neurology Authors: C. Rosso, V. Perlbarg, R. Valabregue, C. Arbizu, S. Ferrieux, B. Alshawan, P. Vargas, A. Leger, C. Zavanone, J.C. Corvol, S. Meunier, S. Lehéricy, Y. Samson Source Type: research

Effects of prefrontal transcranial direct current stimulation on language production in post-stroke aphasia
A successful interplay between prefrontal and domain-specific language areas has been shown to be crucial for language processing. Non-invasive brain stimulation is increasingly being used as a promising therapeutic tool for neurological diseases. The aim of the present study is to investigate the effects of transcranial direct current stimulation (tDCS) of the prefrontal cortex (PFC) on language production in chronic post-stroke aphasic patients.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: M.I. Pestalozzi, M. Di Pietro, G. Gaytanidis, L. Chouiter, L. Spierer, A. Schnider, J.M. Annoni, L.B. Jost Source Type: research

The efficacy of selective transcranial magnetic stimulation with functional near-infrared spectroscopy and intensive speech therapy on individuals with post-stroke aphasia
Introduction: To examine the efficacy of selective repetitive transcranial magnetic stimulation (rTMS) therapy guided by functional near-infrared spectroscopy (fNIRS) combined with intensive speech therapy(ST) on post-stroke patients with aphasia, and right hemisphere high-frequency rTMS combined with intensive ST on patients who were right hemisphere-activated in a language task.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: T. Hara, M. Abo, K. Kakita Source Type: research

The current level of evidence for using transcranial direct current stimulation (tDCS) to improve naming ability in post-stroke aphasia: a critical review
Transcranial Direct Current Stimulation (tDCS) is a non-invasive neuromodulation tool that can be used to manipulate cortical brain activity to induce measurable behavioral changes. Although there is growing evidence that tDCS combined with behavioural language therapy could boost language recovery in patients with post-stroke aphasia, there is great variability in patient characteristics, treatment protocols, and outcome measures in these studies that poses challenges for analyzing the evidence.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 18, 2017 Category: Neurology Authors: Mohammed F. ALHarbi, Susan Armijo-Olivo, Esther S. Kim Source Type: research

Effect of different frequencies in repetitive transcranial magnetic stimulation for the patients with post-stroke motor aphasia
In this study, we applied low and high frequency rTMS targeting the bilateral hemispheres. The purpose of this study is to evaluate the efficacy of two types of rTMS for post-stroke motor aphasia.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: R. Awa, H. Tokimura, H. Yamanaka, Y. Tokimura, S. Etoh, K. Todoroki, K. Takasaki, M. Atsuchi, M. Atsuchi Source Type: research

Personalized functional imaging-guided rTMS on the superior frontal gyrus for post-stroke aphasia: A randomized sham-controlled trial
Aphasia affects approximately one-third of stroke patients and yet its rehabilitation outcomes are often unsatisfactory. More effective strategies are needed to promote recovery.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - August 29, 2023 Category: Neurology Authors: Jianxun Ren, Weijing Ren, Ying Zhou, Louisa Dahmani, Xinyu Duan, Xiaoxuan Fu, Yezhe Wang, Ruiqi Pan, Jingdu Zhao, Ping Zhang, Bo Wang, Weiyong Yu, Zhenbo Chen, Xin Zhang, Jian Sun, Mengying Ding, Jianting Huang, Liu Xu, Shiyi Li, Weiwei Wang, Wuxiang Xie, Source Type: research

Brain stimulation in aphasia rehabilitation: Current state and future projects
Stroke remains the leading cause for severe long-term disability despite all successes in treating or even preventing acute stroke. Persistent language deficits lead not only to impairment in activities of daily living, failure to return to work, and profound personal and family suffering including limited social participation.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: A. Fl öel, R. Darkow, M. Meinzer Source Type: research