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Source: Circulation
Condition: Coronary Heart Disease

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Total 66 results found since Jan 2013.

Seafood Long-Chain n-3 Polyunsaturated Fatty Acids and Cardiovascular Disease: A Science Advisory From the American Heart Association.
on; Council on Cardiovascular Disease in the Young; Council on Cardiovascular and Stroke Nursing; and Council on Clinical Cardiology Abstract Since the 2002 American Heart Association scientific statement "Fish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease," evidence from observational and experimental studies and from randomized controlled trials continues to emerge to further substantiate the beneficial effects of seafood long-chain n-3 polyunsaturated fatty acids and cardiovascular disease. A recent American Heart Association science advisory addressed the specific effect of n-3 polyuns...
Source: Circulation - May 17, 2018 Category: Cardiology Authors: Rimm EB, Appel LJ, Chiuve SE, Djoussé L, Engler MB, Kris-Etherton PM, Mozaffarian D, Siscovick DS, Lichtenstein AH, American Heart Association Nutrition Committee of the Council on Lifestyle and Cardiometabolic Health; Council on Epidemiology and Prevent Tags: Circulation Source Type: research

Erectile Dysfunction as an Independent Predictor of Future Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis.
Abstract Vascular erectile dysfunction (ED) and cardiovascular disease (CVD) share common risk factors including obesity, hypertension, metabolic syndrome, diabetes mellitus, and smoking. ED and CVD also have common underlying pathological mechanisms, including endothelial dysfunction, inflammation, and atherosclerosis.1 Despite these close relationships, the evidence documenting ED as an independent predictor of future CVD events is limited.We therefore leveraged the MESA study (Multi-Ethnic Study of Atherosclerosis), an ethnically diverse, community-based, multisite prospective cohort study, to examine the value...
Source: Circulation - June 11, 2018 Category: Cardiology Authors: Uddin SMI, Mirbolouk M, Dardari Z, Feldman DI, Cainzos-Achirica M, DeFilippis AP, Greenland P, Blankstein R, Billups KL, Miner M, Nasir K, Blaha MJ Tags: Circulation Source Type: research

Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality: An Individual-Level Pooled Analysis of 30 Cohort Studies.
CONCLUSIONS: In pooled global analyses, higher in vivo circulating and tissue levels of LA and possibly AA were associated with lower risk of major cardiovascular events. These results support a favorable role for LA in CVD prevention. PMID: 30971107 [PubMed - as supplied by publisher]
Source: Circulation - April 10, 2019 Category: Cardiology Authors: Marklund M, Wu JHY, Imamura F, Del Gobbo LC, Fretts A, de Goede J, Shi P, Tintle N, Wennberg M, Aslibekyan S, Chen TA, de Oliveira Otto MC, Hirakawa Y, Eriksen HH, Kröger J, Laguzzi F, Lankinen M, Murphy RA, Prem K, Samieri C, Virtanen J, Wood AC, Wong K Tags: Circulation Source Type: research

Use of Genetic Variants Related to Antihypertensive Drugs to Inform on Efficacy and Side Effects.
CONCLUSIONS: Genetic variants can be used to explore the efficacy and side effects of antihypertensive medications. The identified potential effect of nondihydropyridine CCBs on diverticulosis risk could have clinical implications and warrants further investigation. PMID: 31234639 [PubMed - as supplied by publisher]
Source: Circulation - June 24, 2019 Category: Cardiology Authors: Gill D, Georgakis MK, Koskeridis F, Jiang L, Feng Q, Wei WQ, Theodoratou E, Elliott P, Denny JC, Malik R, Evangelou E, Dehghan A, Dichgans M, Tzoulaki I Tags: Circulation Source Type: research

Women's Participation in Cardiovascular Clinical Trials From 2010 to 2017.
CONCLUSIONS: Among cardiovascular trials in the current decade, men still predominate overall, but the representation of women varies with disease and trial characteristics, and has improved in stroke and heart failure trials. PMID: 32065763 [PubMed - in process]
Source: Circulation - February 17, 2020 Category: Cardiology Authors: Jin X, Chandramouli C, Allocco B, Gong E, Lam CSP, Yan LL Tags: Circulation Source Type: research

Exercise-Related Acute Cardiovascular Events and Potential Deleterious Adaptations Following Long-Term Exercise Training: Placing the Risks Into Perspective-An Update: A Scientific Statement From the American Heart Association.
and Stroke Nursing; Council on Clinical Cardiology; and Stroke Council Abstract Epidemiological and biological plausibility studies support a cause-and-effect relationship between increased levels of physical activity or cardiorespiratory fitness and reduced coronary heart disease events. These data, plus the well-documented anti-aging effects of exercise, have likely contributed to the escalating numbers of adults who have embraced the notion that "more exercise is better." As a result, worldwide participation in endurance training, competitive long distance endurance events, and high-intensity interval training...
Source: Circulation - February 25, 2020 Category: Cardiology Authors: Franklin BA, Thompson PD, Al-Zaiti SS, Albert CM, Hivert MF, Levine BD, Lobelo F, Madan K, Sharrief AZ, Eijsvogels TMH, American Heart Association Physical Activity Committee of the Council on Lifestyle and Cardiometabolic Health; Council on Cardiovascula Tags: Circulation Source Type: research

Temporal Trends in the Remaining Lifetime Risk of Cardiovascular Disease Among Middle-Aged Adults Across 6 Decades: The Framingham Study
Conclusions: Over the past 6 decades, mean life expectancy increased and the RLR of ASCVD decreased in the community based, predominantly White Framingham study. The residual burden of ASCVD underscores the importance of continued and effective primary prevention efforts with better screening for risk factors and their effective treatment.PMID:35430874 | DOI:10.1161/CIRCULATIONAHA.121.057889
Source: Circulation - April 18, 2022 Category: Cardiology Authors: Ramachandran S Vasan Danielle M Enserro Vanessa Xanthakis Alexa S Beiser Sudha Seshadri Source Type: research

Blood Pressure Management in the 21st Century: Maximizing Gains and Minimizing Waste.
Abstract The development of effective pharmacological strategies for lowering blood pressure was one of medical science's major success stories of the 20(th) century. Blood pressure was proven beyond doubt to be causally and continuously related to future risk of cardiovascular events,(1) and lowering blood pressure was proven to reduce that risk.(2-4) Pooled data from randomized trials collectively showed that lowering systolic blood pressure by 10 mmHg reduced coronary heart disease risk by about a quarter and risk of stroke by about a third, irrespective of prior disease history, initial blood pressure level, o...
Source: Circulation - November 4, 2013 Category: Cardiology Authors: Rahimi K, Macmahon S Tags: Circulation Source Type: research

Assessing Neighborhood-Level Effects on Disparities in Cardiovascular Diseases.
Abstract Despite declines in mortality from cardiovascular diseases (CVD) and many CVD risk factors, CVD remains the leading cause of death in the US and racial and ethnic disparities persist. In 2010, rates of CVD mortality per 100,000 were: 192.2 for White women; 260.5 for Black women; 278.4 for White men; and 369.2 for Black men(1). In 2009-2010, metrics of ideal cardiovascular health factors (i.e., blood pressure, physical activity, healthy diet, healthy weight, smoking status, and glucose) were noted to be lower for Blacks and Mexican Americans than for Whites or other racial groups(1). In 2012, the following...
Source: Circulation - December 1, 2014 Category: Cardiology Authors: Correa A, Greer S, Sims M Tags: Circulation Source Type: research

Age at Menarche and Risks of Coronary Heart and Other Vascular Diseases in a Large UK Cohort.
CONCLUSIONS: -In this cohort, the relation of age at menarche to vascular disease risk was U-shaped, with both early and late menarche being associated with increased risk. Associations were weaker for cerebrovascular and hypertensive disease than for CHD. PMID: 25512444 [PubMed - as supplied by publisher]
Source: Circulation - December 15, 2014 Category: Cardiology Authors: Canoy D, Beral V, Balkwill A, Wright FL, Kroll ME, Reeves GK, Green J, Cairns BJ Tags: Circulation Source Type: research

Frequent Physical Activity May not Reduce Vascular Disease Risk as Much as Moderate Activity: Large Prospective Study of UK Women.
CONCLUSIONS: -Moderate physical activity is associated with a lower risk of CHD, VTE and cerebrovascular disease than inactivity. However, among active women there is little to suggest progressive reductions in risk of vascular diseases with increasing frequency of activity. PMID: 25688148 [PubMed - as supplied by publisher]
Source: Circulation - February 16, 2015 Category: Cardiology Authors: Armstrong ME, Green J, Reeves GK, Beral V, Cairns BJ Tags: Circulation Source Type: research

A Cluster-Randomized Controlled Trial of a Simplified Multifaceted Management Program for Individuals at High Cardiovascular Risk (SimCard Trial) in Rural Tibet, China, and Haryana, India.
CONCLUSIONS: -The results indicate that the simplified cardiovascular management program improved quality of primary care and clinical outcomes in resource-poor settings in China and India. Larger trials in more places are needed to ascertain potential impacts on mortality and morbidity outcomes. Clinical Trial Registration Information-clinicaltrials.gov. Identifier: NCT01503814. PMID: 26187183 [PubMed - as supplied by publisher]
Source: Circulation - July 17, 2015 Category: Cardiology Authors: Tian M, Ajay V, Dunzhu D, Hameed S, Li X, Liu Z, Li C, Chen H, Cho K, Li R, Zhao X, Jindal D, Rawal I, Ali MK, Peterson ED, Ji J, Amarchand R, Krishnan A, Tandon N, Xu LQ, Wu Y, Prabhakaran D, Yan L Tags: Circulation Source Type: research

Utility of Non-Traditional Risk Markers in Individuals Ineligible for Statin Therapy According to the 2013 ACC/AHA Cholesterol Guidelines.
CONCLUSIONS: -In this generally low-risk population sample, a large proportion of ASCVD events occurred among adults with a 10-yr. cPCE risk <7.5%. We found that the CAC, hsCRP, FH and ABI recommendations by the ACC/AHA cholesterol guidelines (Class IIB) identify small subgroups of asymptomatic population with <7.5% 10 yr. cPCE but with observed ASCVD event rates higher than 7.5% who may warrant statin therapy considerations. PMID: 26224808 [PubMed - as supplied by publisher]
Source: Circulation - July 29, 2015 Category: Cardiology Authors: Yeboah J, Polonsky TS, Young R, McClelland RL, Delaney JC, Dawood F, Blaha MJ, Miedema MD, Sibley CT, Carr JJ, Burke GL, Goff DC, Psaty BM, Greenland P, Herrington DM Tags: Circulation Source Type: research

Examining Dietary Patterns in Relation to Chronic Disease: Matching Measures and Methods to Questions of Interest.
Abstract In this issue of Circulation, Shikany and colleagues add to the growing body of literature on dietary patterns and their relation to health outcomes.(1) The purpose of their paper was to test the hypothesis that dietary patterns extracted through factor analysis are associated with risk of acute coronary heart disease (CHD) in the Reasons for Geographic and Racial Differences in Stroke Study. The authors note that studies examining associations between dietary patterns and CHD in samples with sociodemographic and regional diversity are lacking. Understanding the drivers of health disparities is critically...
Source: Circulation - August 10, 2015 Category: Cardiology Authors: Krebs-Smith SM, Subar AF, Reedy J Tags: Circulation Source Type: research