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Incidence of atrial fibrillation in elderly patients with type 2 diabetes mellitus
CONCLUSIONS: Annually, 1 in 200 elderly Japanese patients with T2D are estimated to develop AF. Because elderly patients with T2D with AF are at an elevated risk for CVD, careful follow-up of this patient subgroup is necessary.TRIAL REGISTRATION NUMBER: NCT00110448.PMID:35361621 | DOI:10.1136/bmjdrc-2021-002745
Source: Atherosclerosis - April 1, 2022 Category: Cardiology Authors: Chisa Matsumoto Hisao Ogawa Yoshihiko Saito Sadanori Okada Hirofumi Soejima Mio Sakuma Izuru Masuda Masafumi Nakayama Naofumi Doi Hideaki Jinnouchi Masako Waki Takeshi Morimoto Source Type: research

Low-Dose Aspirin for Primary Prevention of Cardiovascular Events in Elderly Japanese Patients with Atherosclerotic Risk Factors: Subanalysis of a Randomized Clinical Trial (JPPP-70)
ConclusionsAspirin did not reduce the risk of the primary or secondary outcomes in old patients. Aspirin treatment may have reduced CVEs within a high CVE risk elderly population subgroup. Aspirin treatment in such a group requires caution, because of the increased risk of intracranial hemorrhage, severe extracranial hemorrhage requiring hospitalization or transfusion, and gastrointestinal bleeding in old patients receiving aspirin therapy.Clinical Trial RegistrationThe study is registered at ClinicalTrials.gov [NCT00225849].
Source: American Journal of Cardiovascular Drugs - December 18, 2018 Category: Cardiology Source Type: research