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Safeguarding Against Stroke Risk by Statins
Whereas mighty prospective randomized trials —and meta-analyses of these—rightly command the data used to drive guidelines and daily clinical practice, careful long-term follow-up of closely monitored cohorts can generate crucial discoveries not anticipated in a 5-year study. As just one example, findings from lifelong follow-up in the Ame rican Framingham studies and the Whitehall cohorts in the United Kingdom show a strong association between blood pressure in middle years and dementia in later life.
Source: Mayo Clinic Proceedings - September 1, 2023 Category: Internal Medicine Authors: Adrian J.B. Brady Tags: Editorial Source Type: research

Premature Atrial Contractions
Premature atrial contractions (PACs) can be seen in a broad spectrum of patients with and without heart disease and are often considered benign clinical phenomena. Recent studies have, however, shown an association between PACs and new-onset atrial fibrillation (AF), stroke, and all-cause mortality.1,2 Simultaneously, reporting of the association between cardiac arrhythmias such as AF, atrial structural disease, and cerebrovascular diseases such as stroke and dementia have expanded our understanding of the complex web of interaction between the heart and brain.
Source: Mayo Clinic Proceedings - May 1, 2021 Category: Internal Medicine Authors: Chaitra Janga, Malini Madhavan Tags: Editorial Source Type: research

In reply —Sauna Bathing and Healthy Sweating
We thank Eiser and Brooks for their comments about the health benefits of sauna bathing. Regular sauna bathing has some beneficial effects on blood pressure, cardiometabolic biomarkers, arterial compliance, and cardiovascular function.1 Our prospective studies have shown that higher frequency and duration of sauna bathing are related to a lower risk of cardiovascular mortality, sudden cardiac death, stroke, hypertension, pulmonary diseases, and dementia.1-3 The feelings of relaxation and promotion of mental health and well-being associated with sauna sessions might be linked to the increased production of circulating level...
Source: Mayo Clinic Proceedings - March 31, 2019 Category: Internal Medicine Authors: Jari A. Laukkanen, Tanjaniina Laukkanen, Setor Kunutsor Tags: Letter to the Editor Source Type: research

White Matter Hyperintensities on Magnetic Resonance Imaging: What Is a Clinician to Do?
As a neurologist, I am often asked to see patients because they have a magnetic resonance image (MRI) of the brain showing white matter hyperintensities (WMHs). These patients, and the clinicians who refer them to me, want to know the answers to several questions: What are WMHs and what causes them? Are they the same as a stroke? Are they a marker for impending stroke, dementia, or death? Do they get worse over time and can the progression be slowed? Studies such as the one by Hasan et  al1 in this issue of Mayo Clinic Proceedings have expanded our understanding of the etiology and clinical significance of WMHs.
Source: Mayo Clinic Proceedings - March 1, 2019 Category: Internal Medicine Authors: Jos é G. Merino Tags: Editorial Source Type: research

Palliative Care in Neurology
Palliative medicine is a specialty that focuses on improving the quality of life for patients with serious or advanced medical conditions, and it is appropriate at any stage of disease, including at the time of diagnosis. Neurologic conditions tend to have high symptom burdens, variable disease courses, and poor prognoses that affect not only patients but also their families and caregivers. Patients with a variety of neurologic conditions such as Parkinson disease, dementia, amyotrophic lateral sclerosis, brain tumors, stroke, and acute neurologic illnesses have substantial unmet needs that can be addressed through a combi...
Source: Mayo Clinic Proceedings - October 1, 2017 Category: Internal Medicine Authors: Maisha T. Robinson, Robert G. Holloway Tags: Symposium on neurosciences Source Type: research