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The plasticity of late-onset dementia: A nationwide cohort study in Denmark
DISCUSSION: Most of the observed plasticity in late-onset dementia is associated with a risk decline across successive birth cohorts that is independent of improvements in traditional risk factors.PMID:34569688 | DOI:10.1002/alz.12469
Source: The Journal of Alzheimers Association - September 27, 2021 Category: Psychiatry Authors: Emilie R Hegelund Amar J Mehta Laust H Mortensen Rudi G J Westendorp Source Type: research

Preventing dementia by preventing stroke: The Berlin Manifesto.
This article summarizes the evidence for translation into action. PMID: 31327392 [PubMed - in process]
Source: The Journal of Alzheimers Association - July 24, 2019 Category: Psychiatry Tags: Alzheimers Dement Source Type: research

Blood amyloid levels and risk of dementia in the Ginkgo Evaluation of Memory Study (GEMS): A longitudinal analysis.
We examined baseline plasma β-amyloid (Aβ) levels in relationship to incident dementia during a period of 8.5 years in 2840 subjects age >75 years; 2381 were cognitively normal (CN) and 450 mild cognitive impairment. RESULTS: Increased plasma Aβ1-40 and Aβ1-42 levels were associated with gender (women), age, low education, creatinine levels, history of stroke, and hypertension. CN participants who developed dementia had lower levels of Aβ1-42 and Aβ1-42/Aβ1-40 ratio compared with those who did not. Aβ levels did not predict dementia in mild cognitive impairment participants. DISCUSSION: There was an inv...
Source: The Journal of Alzheimers Association - July 2, 2019 Category: Psychiatry Tags: Alzheimers Dement Source Type: research

Delayed-onset dementia after stroke or transient ischemic attack.
DISCUSSION: Severe SVD contributes importantly to delayed-onset dementia after stroke and/or TIA. Future clinical trials aiming to prevent delayed-onset dementia after stroke and/or TIA should target this high-risk group. PMID: 27327542 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - June 23, 2016 Category: Psychiatry Tags: Alzheimers Dement Source Type: research

Development and validation of a brief dementia screening indicator for primary care.
CONCLUSIONS: The Dementia Screening Indicator is a simple tool that may be useful in primary care settings to identify high-risk patients to target for cognitive screening. PMID: 24491321 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - February 7, 2014 Category: Psychiatry Tags: Alzheimers Dement Source Type: research