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Risk of dementia in elderly patients with the use of proton pump inhibitors.
Authors: Haenisch B, von Holt K, Wiese B, Prokein J, Lange C, Ernst A, Brettschneider C, König HH, Werle J, Weyerer S, Luppa M, Riedel-Heller SG, Fuchs A, Pentzek M, Weeg D, Bickel H, Broich K, Jessen F, Maier W, Scherer M Abstract Drugs that modify the risk of dementia in the elderly are of potential interest for dementia prevention. Proton pump inhibitors (PPIs) are widely used to reduce gastric acid production, but information on the risk of dementia is lacking. We assessed association between the use of PPIs and the risk of dementia in elderly people. Data were derived from a longitudinal, multicenter cohort s...
Source: European Archives of Psychiatry and Clinical Neuroscience - October 25, 2014 Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research

Risk of dementia in elderly patients with the use of proton pump inhibitors
Abstract Drugs that modify the risk of dementia in the elderly are of potential interest for dementia prevention. Proton pump inhibitors (PPIs) are widely used to reduce gastric acid production, but information on the risk of dementia is lacking. We assessed association between the use of PPIs and the risk of dementia in elderly people. Data were derived from a longitudinal, multicenter cohort study in elderly primary care patients, the German Study on Aging, Cognition and Dementia in Primary Care Patients (AgeCoDe), including 3,327 community-dwelling persons aged ≥75 years. From follow-up 1 to follow-up 4 (fol...
Source: European Archives of Psychiatry and Clinical Neuroscience - October 24, 2014 Category: Neuroscience Source Type: research