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Condition: Autoimmune Disease
Procedure: MRI Scan
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Total 65 results found since Jan 2013.
Mitochondrial Myopathy in a 21-Year-Old Man Presenting With Bilateral Lower Extremity Weakness and Swelling
We report a case of a 21-year-old student who developed bilateral lower limb weakness, pain, and swelling diagnosed with mitochondrial myopathy on muscle biopsy. Initial laboratory tests revealed elevated creatinine kinase, brain natriuretic peptide, troponin, myoglobin, and lactic acid and reduced serum bicarbonate. Cardiac workup revealed systolic heart failure with a reduced ejection fraction. Endomyocardial biopsy revealed punctate foci of lymphocytic myocarditis. However, cardiac magnetic resonance imaging did not reveal either myocarditis or an infiltrative cardiac disease. An extensive autoimmune and infection work-...
Source: Primary Care - May 10, 2023 Category: Primary Care Authors: Kavya Bharathidasan Abbie Evans Fabiana Monte Alegre Olmos Fernandez Arunee Tansrisook Motes Kenneth Nugent Source Type: research
A Case of Inflammatory Myopathy in Graft vs Host Disease - A Potential Role for Ibrutinib
Idiopathic inflammatory myopathies are a group of systemic autoimmune conditions with dominant manifestations on skeletal muscle and include the subgroups dermatomyositis, polymyositis, inclusion body myositis and necrotising myopathy. These subgroups share the clinical features of skeletal muscle weakness, raised serum levels of creatine kinase (CK), myopathic changes on electromyography and magnetic resonance imaging, but are distinguished by autoantibody profiles, and importantly by muscle histopathology which reflects the distinct pathogenetic mechanisms [1].
Source: Neuromuscular Disorders - July 4, 2021 Category: Neurology Authors: Michael Wilkinson, David Yeung, Vidya Limaye Tags: Case report Source Type: research
Not just eosinophilic fasciitis
J Med Life. 2021 Jan-Mar;14(1):121-124. doi: 10.25122/jml-2021-0015.ABSTRACTThis case report describes a rare case of progressive muscle weakness in a patient treated for eosinophilic fasciitis (EF) for many years before being diagnosed with a second autoimmune disease: dermatomyositis. Our case is a report of a 65-year-old male diagnosed with eosinophilic fasciitis 7 years before being evaluated in our service at Mayo Clinic in Jacksonville, Florida, due to progressive muscle weakness despite the chronic treatment with methotrexate. Contrast-enhanced magnetic resonance imaging of the lower extremity showed enhancement thr...
Source: Journal of Medicine and Life - March 26, 2021 Category: General Medicine Authors: Razvan Chirila Elena Raluca Cristea Monica Roxana Purcarea Laura Carina Tribus Source Type: research
