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Brain repair by hematopoietic growth factors in the subacute phase of traumatic brain injury.
CONCLUSIONS SCF + G-CSF treatment in the subacute phase of TBI restored TBI-impaired spatial learning and memory, prevented posttraumatic anxiety and risk-taking behavior, inhibited TBI-induced neurodegeneration, and enhanced neural network remodeling. These findings suggest the therapeutic potential of hematopoietic growth factors for brain repair in the subacute phase of TBI. PMID: 29372883 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - January 26, 2018 Category: Neurosurgery Authors: Toshkezi G, Kyle M, Longo SL, Chin LS, Zhao LR Tags: J Neurosurg Source Type: research

Validation of effectiveness of keyhole clipping in nonfrail elderly patients with unruptured intracranial aneurysms.
CONCLUSIONS Keyhole clipping for nonfrail elderly patients with relatively small anterior circulation UIAs did not significantly increase the complication, mortality, or morbidity rate; hospitalization period; or aneurysm recurrence compared with nonelderly patients, and it was associated with improvement in anxiety and depression. Keyhole clipping to treat UIAs in the nonfrail elderly is an effective and long-lasting treatment. PMID: 28059648 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - January 5, 2017 Category: Neurosurgery Authors: Mori K, Wada K, Otani N, Tomiyama A, Toyooka T, Fujii K, Kumagai K, Takeuchi S, Tomura S, Yamamoto T, Nakao Y, Arai H Tags: J Neurosurg Source Type: research