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Specialty: Neurology
Source: Neurology
Condition: Anxiety

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Total 31 results found since Jan 2013.

DNA methylation predicts stroke outcome better: The epigenetic clock is ticking
As a leading cause of disability worldwide, stroke renders people disabled through several mechanisms. Over half of patients have sensorimotor and cognitive deficits, one-third experience depression and social disability, and half never return to work. Our ability to predict recurrent stroke and disability poststroke remains poor despite modern medical advances.1 The uncertainty surrounding the recovery process creates critical knowledge gaps for clinicians deciding on the most appropriate care plan, and leads to substantial anxiety for patients and their families. Identification of factors that affect prognosis after stro...
Source: Neurology - August 21, 2017 Category: Neurology Authors: Wang, L., Pare, G., Rundek, T. Tags: EDITORIALS Source Type: research

HELIAD study: Dementia prevalence in Greece (P3.095)
Conclusions:The prevalence of dementia and its subtypes in Greece is similar or at the lower range of that reported in many other European countries and globally. In our sample, increased age and decreased level of education status, but not gender, were predictive of a diagnosis of dementia with age being the strongest predictive factor.Study Supported by:Funding/Support: IIRG-09-133014 from the Alzheimer’s Association; 189 10276/8/9/2011 from the ESPA-EU program Excellence Grant (ARISTEIA) which is co-funded by the European Social Fund and Greek National resources; and Y2β/o.51657/14.4.2009 from the Ministry fo...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Sakka, P., Kosmidis, M., Yannakoulia, M., Dardiotis, E., Hadjigeorgiou, G., Scarmeas, N. Tags: Aging and Dementia: Epidemiologic Studies Source Type: research

Post-acute delivery of GABAA receptor alpha5-antagonist S44819 promotes motor-coordination recovery, prevents secondary brain atrophy and reduces astrocytic scar formation after transient middle cerebral artery occlusion in mice (P3.109)
Conclusions:Our data provide strong evidence that S44819 enhances neurological recovery in the post-acute stroke phase.Disclosure: Dr. Wang has nothing to disclose. Dr. Sanchez-Mendoza has nothing to disclose. Dr. de Carvalho has nothing to disclose. Dr. Kaltwasser has nothing to disclose. Dr. Machado has received personal compensation as an employee of Servier (France), Dr. Doeppner has nothing to disclose. Dr. Bassetti has received personal compensation for activities with Servier as an Advisory Board Member. Dr. Bassetti has received research support from Servier. Dr. Hermann has received personal compensation for activ...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Wang, Y.-c., Sanchez-Mendoza, E., de Carvalho, T. S., Kaltwasser, B., Machado, P., Doeppner, T. R., Bassetti, C. L., Hermann, D. M. Tags: Cerebrovascular Disease and Interventional Neurology Poster Discussion Session Source Type: research

Hemorrhagic stroke following consumption of energy drink (P3.271)
Conclusions:Apart from high levels of caffeine, Red Line also contains multiple other compunds like B-Phenylethylamine hydrochloride, Yohimbine, Toothed club moss extract and 5-hydroxytryptophan. Many of these agents are known to have sympathomimetic activity of their own. There is limited awareness of the potential interactions between these agents, and their safety when combined with caffeine. The Red Line bottle recommends that people with hypertension not use it, but our patient had not read these instructions. In conclusion, intracranial hemorrhage must be added to the list of side effects associated with energy drink...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Venkatraman, A., Khawaja, A., Shapshak, A. Tags: Cerebrovascular Disease Case Reports II Source Type: research

Stroke risk factors, post stroke anxiety and neurocognitive function (s36.003)
Conclusions:As in other contexts, the prevalence of clinically significant anxiety after stroke in this low income population is high. It is frequently co-morbid with depression and associated with cognitive impairment in stroke survivors.Study Supported by:National Institute of Neurological Disorders and Stroke (NINDS-U01 NS079179) and GACD.Disclosure: Dr. Owolabi has nothing to disclose. Dr. Akinyemi has nothing to disclose. Dr. Akinyemi has nothing to disclose. Dr. Gebregziabher has nothing to disclose. Dr. Uvere has nothing to disclose. Dr. Ovbiagele has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Owolabi, M., Akinyemi, R., Akinyemi, J., Gebregziabher, M., Uvere, E., Ovbiagele, B. Tags: Cerebrovascular Disease and Interventional Neurology: Epidemiology Source Type: research

Predictive Variables of Cognitive Dysfunction in Patients with Lupus (P1.340)
Conclusions:Duration of disease and low educational level are predictors of CD in patients with SLE. Depression and anxiety did not influence cognitive performance. Although cardiovascular comorbidity is a risk factor for dementia in general population, those variables might play a minor role in SLE patients.Study Supported by:Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) and São Paulo Research Foundation (FAPESP) (grant #2015/08833-7) supported this study.Disclosure: Dr. Alessi has nothing to disclose. Dr. Dutra Antonio has nothing to disclose. Dr. Maria has nothing...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Alessi, H., Dutra, L. A., Maria, L., Xavier, P., Couce, P., Kayser, C., Barsottini, O. Tags: CNS Inflammatory Diseases and Differential Diagnosis I Source Type: research

Identification of a novel TRPA1 mutation associated with carbamazepine-responsive cramp-fasciculation syndrome (S45.008)
Conclusions:Autosomal dominant CFS is associated with a novel mutation in the putative selectivity filter of TRPA1. These findings further clarify the functional role of human TRPA1, and underscore the importance of this ion channel as a potential therapeutic target.Study Supported by: This work was supported by the National Institute of Neurological Disorders and Stroke of the National Institute of Health (R01NS079388). MJN also receives support from the New York Stem Cell Foundation.Disclosure: Dr. Biller has nothing to disclose. Dr. Paisan-Ruiz has nothing to disclose. Dr. Gilbert has nothing to disclose. Dr. Chaouni ha...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Biller, T. M., Paisan-Ruiz, C., Gilbert, R. M., Chaouni, R., Nirenberg, M. J. Tags: Peripheral Nerve Disorders Source Type: research

Have clinicians adopted the use of brain MRI for patients with TIA and minor stroke?
Conclusions: Within a national health system, about 40% of patients with TIA/minor stroke had MRI performed within 2 days. Performance of MRI appeared to be influenced by several patient and facility-level variables, suggesting that there has been partial acceptance of the previous guideline that endorsed MRI for patients with TIA.
Source: Neurology - January 15, 2017 Category: Neurology Authors: Chaturvedi, S., Ofner, S., Baye, F., Myers, L. J., Phipps, M., Sico, J. J., Damush, T., Miech, E., Reeves, M., Johanning, J., Williams, L. S., Arling, G., Cheng, E., Yu, Z., Bravata, D. Tags: CT, MRI, All Cerebrovascular disease/Stroke ARTICLE Source Type: research

Neuro-Psychiatry Diseases Predisposing to Mental Status Changes in Patients with Community-Acquired Pneumonia (P1.313)
Conclusions: This study indicates that MSC is frequent in patients with CAP presenting to hospital emergency departments. The etiology of MSC is diverse, with approximately half of the cases due to neuro-psychiatric conditions. In patients presenting to the emergency department with MSC, a high index of suspicion should be maintained regarding the diagnosis of pneumonia.Disclosure: Dr. Kolikonda has nothing to disclose. Dr. Wiemken has nothing to disclose. Dr. Arnold has nothing to disclose. Dr. Nakamatsu has nothing to disclose. Dr. Raghuram has nothing to disclose. Dr. Ramirez has nothing to disclose. Dr. Peyrani has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Kolikonda, M., Wiemken, T., Arnold, F., Nakamatsu, R., Raghuram, A., Ramirez, J., Peyrani, P. Tags: Other Bacterial Infections Source Type: research

A Survey of Functional Movement Disorders at the National Institutes of Health (P1.073)
OBJECTIVE: To better characterize the clinical presentation of functional movement disorders. BACKGROUND: Functional (psychogenic) movement disorders are receiving greater attention as valid and treatable neurologic disorders. Unfortunately, the often long list of complaints with variable presentations may hamper timely diagnosis and treatment. METHODS: We reviewed 113 charts retrospectively of patients presenting to the National Institutes of Health. Patients were referred from 44 states and the District of Columbia, with the majority presenting from the local Washington D.C. metropolitan area. Most patients were diagnose...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Ahmad, O., Maurer, C., Villegas, M. A. F., Lungu, C., Hallett, M. Tags: Movement Disorders: Miscellaneous Source Type: research

Nursing Home Residents with Seizure Disorders/Epilepsy: Prevalence, Characteristics, and Treatment Patterns (P1.080)
Conclusions: NHRs with seizure disorder/epilepsy have substantial physical and cognitive impairment. Nearly half were prescribed combination AED therapy, and >20[percnt] took 蠅3 different AEDs, suggesting refractory epilepsy. Additional research is needed to assess treatment outcomes and further define optimal care in this population.Disclosure: Dr. Zarowitz has nothing to disclose. Dr. Allen has nothing to disclose. Dr. OShea has nothing to disclose. Dr. Wang has nothing to disclose. Dr. Semenchuk has nothing to disclose. Dr. Barghout has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Zarowitz, B., Allen, C., OShea, T., Wang, Z., Semenchuk, M., Barghout, V. Tags: Epilepsy/Clinical Neurophysiology: Geriatric Epilepsy, Epidemiology, and Health Services Source Type: research

A Randomized Sham-Controlled Trial of Continuous Positive Airway Pressure in Patients Undergoing Intensive Inpatient Rehabilitation after Acute Stroke (P3.308)
Conclusions: A sham-controlled CPAP trial among stroke rehabilitation patients is feasible and treatment with CPAP may benefit recovery, especially of cognitive function. Tolerance and adherence must be improved before the full benefits of CPAP on functional recovery can be accurately assessed in larger trials.Disclosure: Dr. Khot has received research support from Philips Respironics. Dr. Davis has nothing to disclose. Dr. Crane has nothing to disclose. Dr. Patricia has nothing to disclose. Dr. Li Lue has nothing to disclose. Dr. Claflin has nothing to disclose. Dr. Becker has received research support from NIH and AHA. D...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Khot, S., Davis, A., Crane, D., Patricia, T., Li Lue, D., Claflin, E., Becker, K., Longstreth, W. T., Watson, N., Billings, M. Tags: Neurorehabilitation Source Type: research

Sleep duration is associated with worse neurocognitive function in Hispanic/Latinos: Results of the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) (I9-4A)
CONCLUSIONS: Sleep duration had an inverted J-shaped curvilinear association with neurocognitive function, such that those with longer sleep duration had worse neurocognitive scores. Study Supported by: The Hispanic Community Health Study/Study of Latinos was carried out as a collaborative study supported by contracts from the National Heart, Lung, and Blood Institute (NHLBI) to the University of North Carolina (N01-HC65233), University of Miami (N01-HC65234), Albert Einstein College of Medicine (N01-HC65235), Northwestern University (N01-HC65236), and San Diego State University (N01-HC65237). The following Institutes/Cent...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Ramos, A., Tarraf, W., Daviglus, M., Davis, S., Gallo, L., Mossavar-Rahmani, Y., Penedo, F., Redline, S., Rundek, T., Sacco, R., Sotres-Alvarez, D., Wright, C., Zee, P., Gonzalez, H. Tags: Treating Dementia in an Age of Mixed Disease Data Blitz Presentations Source Type: research

Sleep duration is associated with worse neurocognitive function in Hispanic/Latinos: Results of the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) (P1.100)
CONCLUSIONS: Sleep duration had an inverted J-shaped curvilinear association with neurocognitive function, such that those with longer sleep duration had worse neurocognitive scores. Study Supported by: The Hispanic Community Health Study/Study of Latinos was carried out as a collaborative study supported by contracts from the National Heart, Lung, and Blood Institute (NHLBI) to the University of North Carolina (N01-HC65233), University of Miami (N01-HC65234), Albert Einstein College of Medicine (N01-HC65235), Northwestern University (N01-HC65236), and San Diego State University (N01-HC65237). The following Institutes/Cent...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Ramos, A., Tarraf, W., Daviglus, M., Davis, S., Gallo, L., Mossavar-Rahmani, Y., Penedo, F., Redline, S., Rundek, T., Sacco, R., Sotres-Alvarez, D., Wright, C., Zee, P., Gonzalez, H. Tags: Neuroepidemiology: Cerebrovascular Disease, Critical Care, Epilepsy, Child Neurology, and Sleep Source Type: research

Post-stroke depression (PSD) in sub-Saharan Africans- validation of the Japanese stroke scale for depression. (JSS-D). (P7.129)
CONCLUSIONS:JSS-D could be used for PSD with acceptable sensitivity and specificity in sub-Saharan Africans. Study Supported by:NONEDisclosure: Dr. Imarhiagbe has nothing to disclose. Dr. Afolabi has nothing to disclose. Dr. Kubeyinje has nothing to disclose. Dr. AKEMOKWE has nothing to disclose. Dr. Odiase has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Imarhiagbe, F., Afolabi, O., Kubeyinje, A., Akemokwe, F., Odiase, F. Tags: Cerebrovascular Disease and Interventional Neurology: Stroke, Depression, and Anxiety Source Type: research