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Revascularisation for Symptomatic Peripheral Artery Disease: External Applicability of the VOYAGER PAD Trial
CONCLUSION: Among patients in routine clinical practice, 27.1% were eligible for the VOYAGER PAD trial. These patients were older, had more severe vascular symptoms, higher bleeding risk, and worse prognosis than trial participants.PMID:34924303 | DOI:10.1016/j.ejvs.2021.10.026
Source: PubMed: Eur J Vasc Endovasc ... - December 20, 2021 Category: Surgery Authors: Mette S øgaard Peter B Nielsen Flemming Skj øth Torben B Larsen Nikolaj Eldrup Source Type: research

Editorial Commentary: The Current Evidence in Support of Tranexamic Acid in Arthroscopic Surgery Is Poor
Tranexamic acid (TXA) has been used to treat severe bleeding events for nearly 60 years and is on the list of World Health Organization essential medicines. Initially, it was described to treat heavy menstrual bleeding, but it is now used for a variety of applications. In orthopedic surgery, TXA is commonly used to reduce bleeding after total joint arthroplasty and spine surgery. The use of TXA for joint arthroplasty has been principally endorsed by various orthopedic societies, but they have also criticized a lack of evidence for high-risk patients with a history of pulmonary embolus, vascular stents, stroke, transient is...
Source: Arthroscopy - Journal of Arthroscopic and Related Surgery - February 1, 2022 Category: Surgery Authors: Erik Hohmann Tags: Editorial Commentary Source Type: research

Protamine for Heparin Reversal After Carotid Endarterectomy is Significantly Underutilised: Results from a UK National Survey
Protamine sulphate is widely used to reverse anticoagulation with heparin after various surgical and interventional procedures, and is currently the only drug licensed for this indication. Reversal of intra-operative heparin after carotid endarterectomy (CEA) to reduce the incidence of post-operative bleeding complications, particularly re-exploration for neck haematoma (NH) with airway compromise, has received renewed attention in recent years. Two meta-analyses have shown that intra-operative heparin reversal can be done without increasing the risk of post-operative stroke, myocardial infarction (MI), or death.
Source: European Journal of Vascular and Endovascular Surgery - February 17, 2022 Category: Surgery Authors: Aminder A. Singh, Jonathan R. Boyle, Ian Chetter, Florian Falter Tags: Research Letter Source Type: research

Mirror Mirror on the Wall, Which Is the Most Protective Antithrombotic Therapy of Them All?
Antiplatelet therapy remains a matter of controversy in patients undergoing carotid endarterectomy (CEA). It is still not clear whether the benefit of dual antiplatelet therapy (DAPT) in terms of peri-procedural stroke is counterbalanced by the increased risk of bleeding. To answer this question, Ku et  al.1 aimed to add new information compared with a recently published meta-analysis.2,3 Overall data from 47 411 patients (30% receiving DAPT; mixed symptomatic status) reported in 11 studies (two randomised controlled trials [RCTs]) were included.
Source: European Journal of Vascular and Endovascular Surgery - March 2, 2022 Category: Surgery Authors: Barbara Rantner, Gert J. de Borst Tags: Invited Commentary Source Type: research

Minimal access compared to sternotomy for aortic root and arch surgery
CONCLUSION: The partial upper sternotomy approach is safe and feasible for aortic root and arch surgery with morbidity and mortality rates similar to full sternotomy, with the advantages of less blood loss and transfusions need, faster extubation, and shorter length of hospital stay.PMID:35255771
Source: Acta Chirurgica Belgica - March 8, 2022 Category: Surgery Authors: Anastasia Boudart Alaaddin Yilmaz Abdullah Kaya Source Type: research

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