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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Bleeding

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Total 88 results found since Jan 2013.

Cerebellar Hemorrhage Following an Uncomplicated Lumbar Spine Surgery: Case Report
We present a case of remote cerebellar hemorrhage following uncomplicated lumbar spinal decompression and fusion without CSF leakage.
Source: Journal of Stroke and Cerebrovascular Diseases - May 14, 2019 Category: Neurology Authors: Ryan C. Hofler, Michael P. Wemhoff, Stephen J. Johans, Russ P. Nockels Tags: Case Report Source Type: research

Cerebral Hemorrhage of a 50-Year-Old Female Patient with Polycythemia Vera
Polycythemia vera is a chronic myeloproliferative neoplasm, which is primarily characterized by elevated erythrocyte count with the risk of thrombosis, hemorrhage, and vasomotor symptoms. More common reported about bleeding events are gastrointestinal, mucosal, and cutaneous bleeding. Spontaneous cerebral hemorrhage/bleeding is seldom reported. Here, we report the case of a 50-year-old female with polycythemia vera who developed a spontaneous cerebral hemorrhage. She improved significantly after hydroxyurea agent and red cell apheresis, and the hematocrit decreased from 74% to 40%.
Source: Journal of Stroke and Cerebrovascular Diseases - May 20, 2019 Category: Neurology Authors: Lei Chen, Han Xiao, Zhiping Hu Tags: Case Report Source Type: research

Intraoperative Aneurysm Rupture during Resection for Presumed Metastasis
A 54-year-old male with metastatic melanoma, including a presumed brain metastasis underwent elective surgery when there was sudden onset of extensive bleeding upon resection. An emergent cerebral angiogram revealed a fusiform left posterior cerebral artery aneurysm. Malignant melanoma commonly metastasizes to the brain and has shown to assume a wide variety of appearances with involvement of almost any intracranial structures. The unexpected intraoperative finding required immediate action and strategic rethinking.
Source: Journal of Stroke and Cerebrovascular Diseases - August 8, 2019 Category: Neurology Authors: Anna L. K ühn, Katyucia de Macedo Rodrigues, Ajit S. Puri Tags: Case Report Source Type: research

Intracranial Hemorrhage Diagnosed with Transcranial Ultrasound in a Comatose, Postliver Transplant Patient
We report a case of an intracranial hemorrhage first suspected during a trans-cranial Doppler assessment of a postorthotopic liver transplant patient. The patient was at considerable risk of bleeding, due to a primary graft nonfunction, but he had also elevated ammonium levels, justifying the comatose state, and no focal neurological deficits.
Source: Journal of Stroke and Cerebrovascular Diseases - September 4, 2019 Category: Neurology Authors: Amedeo Bianchini, Rocco D'Andrea, Berin Lepic, Lorenzo Querci, Cristiana Laici, Antonio Siniscalchi Tags: Case Report Source Type: research

Cryptogenic Intracranial Hemorrhagic Strokes Associated with Hypervitaminosis E and Acutely Elevated α-Tocopherol Levels
Objectives: Up to 41% of intracerebral hemorrhages (ICH) are considered cryptogenic despite a thorough investigation to determine etiology. Certain over-the-counter supplements may increase proclivity to bleeding, and we hypothesize that specifically vitamin E may have an association with ICH and acutely elevated serum levels of α-tocopherol. Our aim is to report 3 cases of recently admitted patients with hypervitaminosis E and otherwise cryptogenic ICH. Methods: At our institution between January and December 2018, 179 patients were admitted with ICH with 73 imputed to be “cryptogenic” (without clear etiology as per ...
Source: Journal of Stroke and Cerebrovascular Diseases - March 5, 2020 Category: Neurology Authors: Nicole K. Le, Tigran Kesayan, Jane Y. Chang, David Z. Rose Source Type: research

Cerebral Small Vessel Disease among US minority Survivors of Intracerebral Hemorrhage
Black and Hispanic survivors of Intracerebral Hemorrhage (ICH) are at higher risk of recurrent intracranial bleeding when compared to their white counterparts. While established differences in hypertension severity after ICH play a role, they do not fully account for this health disparity. MRI-based markers of chronic Cerebral Small Vessel Disease (CSVD) are consistently associated with increased risk of recurrent ICH. We therefore sought to investigate whether differences in CSVD subtype and/or severity exist among self-reported race/ethnicity groups.
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Juan Pablo Castello Tags: Poster 15 Source Type: research

Is smoking a risk factor for bleeding in adult men with cerebral arteriovenous malformations? A single-center regression study from China
To assess whether smoking increases the risk of bleeding in patients with cerebral arteriovenous malformations (CAVM).
Source: Journal of Stroke and Cerebrovascular Diseases - August 15, 2020 Category: Neurology Authors: Shuai Zhang, Chenguang Zhou, Dong Liu, Yongjun Piao, Fuqiang Zhang, Jie Hu, Zongqian Ma, Zhanyang Wei, Weisheng Zhu, Ming Lv Source Type: research

Clinical Trial Based Rationale for the Successful Use of DOAC in the Treatment of Cerebral Venous Sinus Thrombosis (CVST): A Case Report
In cerebral venous sinus thrombosis (CVST), venous sinus occlusion increases venous pressure and disrupts venous return, resulting in progression to venous infarction and venous hemorrhage, with poor neurologic outcome. Therefore, early recanalization of the major venous sinus is critical.Anticoagulant therapy with continuous intravenous infusion of heparin and subsequent oral anticoagulant administration is the recommended first line of treatment for CVST. Some large clinical trials for venous thromboembolism (VTE) have shown that direct oral anticoagulant (DOAC) is non-inferior to the standard therapy with heparin or war...
Source: Journal of Stroke and Cerebrovascular Diseases - September 3, 2020 Category: Neurology Authors: Toshiaki Bando, Yasushi Ueno, Daisuke Shimo, Takahiro Kuroyama, Kazuyuki Mikami, Shinya Hori, Osamu Hirai Tags: Case Report Source Type: research

Aspirin Use and Risk of Subdural Hematoma: Updated Meta-Analysis of Randomized Trials
Subdural hematomas are an uncommon, but a serious, bleeding complication of antithrombotic therapies. We update our previous inconclusive meta-analysis to better estimate the risk of subdural hematoma associated with aspirin use.
Source: Journal of Stroke and Cerebrovascular Diseases - June 13, 2021 Category: Neurology Authors: Robert G. Hart, Lesly A. Pearce, Philip B. Gorelick, Ben J. Connolly, Luciana Catanese Source Type: research

Systemic Inflammation Response Index and Systemic Immune-inflammation Index for Predicting the Prognosis of Patients with Aneurysmal Subarachnoid Hemorrhage
An aneurysmal subarachnoid hemorrhage (aSAH) can result in disability and high mortality.1 Re-bleeding, poor admission neurologic status, thick SAH, vasospasm, and delayed cerebral ischemia (DCI) are known as predicting factors for exacerbated prognosis of aSAH.2 –5 Similar to other cerebrovascular diseases, aSAH can causes a pronounced peripheral inflammatory/immune response. Systemic changes are also associated with outcomes of patients with SAH.6,7 Although the exact mechanism has not yet been fully revealed, inflammation is known to plays an important role in the progress of aSAH by inducing early brain damage, vasos...
Source: Journal of Stroke and Cerebrovascular Diseases - May 22, 2021 Category: Neurology Authors: Seonyong Yun, Ho Jun Yi, Dong Hoon Lee, Jae Hoon Sung Source Type: research

“Asymptomatic” Moyamoya Angiopathy: Is it Truly Asymptomatic?
Moyamoya angiopathy (MMA) is a chronic progressive occlusive intracranial vasculopathy characterized by angiographic findings of stenosis or occlusion at the terminal portion of the internal carotid artery (ICA) or proximal anterior cerebral artery (ACA) and/or middle cerebral artery (MCA) together with the abnormal vascular network (classically appears to be like “puff of smoke”) at the base of the brain.1,2 “Asymptomatic” MMA has been defined by previous absence of clinical and radiological evidence of ischemic or hemorrhagic episode in an angiographically proven MMA patient who are neurologically free, excluding...
Source: Journal of Stroke and Cerebrovascular Diseases - March 31, 2022 Category: Neurology Authors: Shambaditya Das, Biman Kanti Ray, Ritwik Ghosh, Souvik Dubey Source Type: research

P2Y12 reaction units and ischemic and bleeding events after neuro-endovascular treatment
To investigate the associations of perioperative P2Y12 reaction units (PRU) measured using VerifyNow with ischemic and bleeding events, and to determine the PRU threshold in the setting of elective neuro-endovascular treatment (EVT) for intracranial/extracranial vascular disease in patients taking aspirin and clopidogrel.
Source: Journal of Stroke and Cerebrovascular Diseases - July 15, 2022 Category: Neurology Authors: Kyohei Fujita, Shoko Fujii, Sakyo Hirai, Hiroto Yamaoka, Mariko Ishikawa, Jun Karakama, Kazunori Miki, Masataka Yoshimura, Shigeru Nemoto, Kazutaka Sumita Source Type: research

Tranexamic acid as a novel adjunct in the management of vessel perforation complicating Endovascular Clot Retrieval
To assess the safety and utility of tranexamic acid (TXA) as an adjunct salvage therapy in iatrogenic vessel perforation complicating endovascular clot retrieval. Iatrogenic vessel perforation and extravasation are known and potentially fatal complications of endovascular clot retrieval (ECR). Various methods of establishing haemostasis post perforation have been reported. TXA is widely utilised intraoperatively to reduce bleeding in various surgical specialities. The use of TXA in endovascular procedures has not been previously described in the literature.
Source: Journal of Stroke and Cerebrovascular Diseases - April 4, 2023 Category: Neurology Authors: Kerelus Morkos, Julian Maingard, Christen Barras, Hong Kuan Kok, Jonathan Hall, Jeremy Russell, Vincent Thijs, Lee-Anne Slater, Winston Chong, Ronil Chandra, Ashu Jhamb, Mark Brooks, Hamed Asadi Source Type: research