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Safety of recanalization therapy in acute ischemic stroke patients on direct oral anticoagulant therapy: An updated systematic review and meta-analysis
Yanxing Zhang, Huan Tang, Xiaohong Gui, Ye Du, Chenglong WuAnnals of Indian Academy of Neurology 2022 25(6):1036-1046 This review provides an updated assessment of the safety of recanalization therapy for Acute Ischemic Stroke (AIS) patients receiving direct oral anticoagulants (DOAC) therapy. We checked the literature for published observational from 1st January 1950 to 31st March 2021. The rate of symptomatic intracerebral hemorrhage (sICH), arterial recanalization rate, good functional recovery, and mortality at 3 months were investigated, and data were expressed as Risk ratio (RR) with a 95% confidence inte...
Source: Annals of Indian Academy of Neurology - December 3, 2022 Category: Neurology Authors: Yanxing Zhang Huan Tang Xiaohong Gui Ye Du Chenglong Wu Source Type: research

Risk and prognostic factors in perinatal hemorrhagic stroke
Conclusion: Our findings showed that PHS was much more common in preterm infants. Mucosal bleeding and multiple lobes involvement were more common in term infants. PHS has high morbidity and mortality rates. Small for gestational age and mucosal bleeding were more common in infants who are dead.
Source: Annals of Indian Academy of Neurology - April 28, 2021 Category: Neurology Authors: H ü seyin Ç aksen Fatma Tuba K ö seoglu Ahmet Sami G ü ven H ü seyin Altunhan Mehmet Sinan Iyisoy Saim A ç ikg ö zoglu Source Type: research

The Efficacy and Safety of Intravenous Thrombolysis in Older Chinese Patients with Acute Ischemic Stroke
Ming Xu, Jiamei Guo, Xianming Tao, Kebin ZengNeurology India 2021 69(1):91-96 To study the efficacy and safety of intravenous thrombolysis for the older acute ischemic stroke patients, clinical data were prospectively analyzed from 168 patients with acute ischemic stroke including 42 older adult patients (ET group), 66 younger patients (NET group) treated with rt-PA, and 60 older adult patients treated without rt-PA (ENT group). Stroke severity was assessed with an NIHSS score at baseline, 1-day and 14-day after treatment. Functional outcomes were evaluated by the modified Rankin scale and a Barthel index. Adverse effects...
Source: Neurology India - February 24, 2021 Category: Neurology Authors: Ming Xu Jiamei Guo Xianming Tao Kebin Zeng Source Type: research

Critical Issues and Recent Advances in Anticoagulant Therapy: A Review
Angelika Batta, Bhupinder S Kalra, Raj KhirasariaNeurology India 2019 67(5):1200-1212 As the population is aging, clinicians are coming across more patients with atrial fibrillation and venous thromboembolism requiring anticoagulation to prevent stroke and systemic embolisms. Due to a high prevalence and unfavorable consequences, managing thromboembolic diseases have become areas of clinical concern. Traditional anticoagulants like heparin, low molecular weight heparin and warfarin have been used for the prevention and treatment of venous and arterial thromboses. But, issues of bleeding, parenteral route of administration...
Source: Neurology India - November 18, 2019 Category: Neurology Authors: Angelika Batta Bhupinder S Kalra Raj Khirasaria Source Type: research