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Source: Canadian Journal of Cardiology
Condition: Bleeding
Countries: Canada Health

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Total 38 results found since Jan 2013.

An Invasive vs a Conservative Approach in Elderly Patients with Non –ST-Segment Elevation Myocardial Infarction: Systematic Review and Meta-Analysis
Conclusion The overall benefit with invasive strategy comes from the data of observational studies that are prone to selection bias. We believe that there is a need for a large randomized study in the elderly patients regarding management of NSTEMI.
Source: Canadian Journal of Cardiology - February 21, 2018 Category: Cardiology Source Type: research

Design of a Randomized Placebo-Controlled Trial to Assess Dabigatran and Omeprazole in Patients with Myocardial Injury after Noncardiac Surgery (MANAGE)
Conclusion MANAGE is the first randomized controlled trial to evaluate a potential treatment of patients who suffered MINS.
Source: Canadian Journal of Cardiology - February 3, 2018 Category: Cardiology Source Type: research

Aortic Arch Reconstructive Surgery with Conventional Techniques versus Frozen Elephant Trunk: A Systematic Review and Meta-Analysis
Conclusion Current evidence suggests that FET surgery is associated with lower mortality in patients with thoracic aneurysmal disease and dissections, without a significant increase in stroke, bleeding or operative times. However, the risk of spinal cord ischemia is increased in FET patients. A well powered randomized trial is needed to evaluate this evolving field. Teaser To our knowledge, we have performed the most detailed meta-analysis for the use of Frozen Elephant Trunk (FET) surgery, yielding a systematic review with the most number of patients studied. Our systematic review and meta-analysis uses the most up to dat...
Source: Canadian Journal of Cardiology - December 26, 2017 Category: Cardiology Source Type: research

Invasive or Conservative Approach in Elderly Patients with Non-ST-segment Elevation Myocardial Infarction: Systematic Review and Meta-Analysis
Conclusion The “overall” benefit with “invasive” strategy comes from the data of observational studies that are prone to selection bias. We believe that there is a need for a large randomised study in the elderly patients regarding management of NSTEMI. Teaser Trials comparing invasive with conservation treatment for elderly patients presenting with NSTEMI are limited resulting in considerable variation in the management of such patients. In the current systematic review, we tried to consolidate the current evidence on these 2 modes of treatment. There was a reduction in mortality with the invasive approach. Howeve...
Source: Canadian Journal of Cardiology - December 6, 2017 Category: Cardiology Source Type: research

Antiplatelet Effect of Different Loading Doses of Ticagrelor in Patients With Non –ST-Elevation Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: The APELOT Trial
Conclusions Doubling the ticagrelor LD achieved faster onset and greater platelet inhibition without an increase in adverse events in patients with NSTE-ACS undergoing PCI.
Source: Canadian Journal of Cardiology - December 3, 2017 Category: Cardiology Source Type: research

The Relationship Between Cardiologist Care and Clinical Outcomes in Patients With New-Onset Atrial Fibrillation
Conclusions Cardiologist care was associated with a reduction in death in patients with new-onset AF. Further study to obtain a greater understanding of the processes of care associated with the observed survival improvement is warranted.
Source: Canadian Journal of Cardiology - December 3, 2017 Category: Cardiology Source Type: research

Antiplatelet Effect of Different Loading Doses of Ticagrelor in Non-ST-Elevation Acute Coronary Syndrome Patients Undergoing PCI: The APELOT Trial
Conclusions Doubling the ticagrelor loading dose achieved faster onset and greater platelet inhibition without an increase in adverse events in patients with NSTE-ACS undergoing PCI.
Source: Canadian Journal of Cardiology - September 13, 2017 Category: Cardiology Source Type: research

Transcatheter vs Surgical Aortic Valve Replacement for Aortic Stenosis in Low-Intermediate Risk Patients: A Meta-analysis
Conclusions Although there was no difference in 30-day and late mortality, the rate of complications differed between TAVR and SAVR in the low-intermediate surgical risk population.
Source: Canadian Journal of Cardiology - August 25, 2017 Category: Cardiology Source Type: research