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Condition: Asthma
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IL-24 Contributes to Neutrophilic Asthma in an IL-17A-Dependent Manner and Is Suppressed by IL-37
CONCLUSIONS: IL-24 aggravated neutrophilic airway inflammation by increasing epithelium-derived IL-17A production, which could be suppressed by IL-37. Targeting the IL-24/IL-17A signaling axis is a potential strategy, and IL-37 is a potential candidate agent for alleviating neutrophilic airway inflammation in asthma.PMID:36174993 | PMC:PMC9523421 | DOI:10.4168/aair.2022.14.5.505
Source: Allergy, Asthma and Immunology Research - September 29, 2022 Category: Allergy & Immunology Authors: Kang-Ni Feng Ping Meng Min Zhang Xiao-Ling Zou Shuang Li Chu-Qin Huang Ke-Fang Lai Hong-Tao Li Tian-Tuo Zhang Source Type: research
