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Condition: Renal Failure
Drug: Metformin

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Total 653 results found since Jan 2013.

Appraisal of guidelines for managing contrast medium in patients with metformin: consensuses, controversies, and gaps
ConclusionsMost guidelines recommend withdrawing metformin before using contrast agents in diabetic patients with severely impaired kidney function but disagree on the renal function thresholds. Furthermore, the gaps regarding discontinuing metformin with moderate renal impairment (30  mL/min/1.73 m2 <  eGFR <  60 mL/min/1.73 m2) must be considered in future studies.Key Points•Guidelines involving metformin and contrast agents are reliable and optimal.•Most guidelines advocate discontinuing metformin before using contrast agents in diabetic patients with advanced renal failure, but there are controversi...
Source: European Radiology - May 3, 2023 Category: Radiology Source Type: research

Metforminassosiert laktacidose
Tidsskr Nor Laegeforen. 2023 Feb 20;143(3). doi: 10.4045/tidsskr.22.0719. Print 2023 Feb 21.ABSTRACTBACKGROUND: Metformin accumulation is associated with lactic acidosis and haemodynamic instability.CASE PRESENTATION: A woman in her seventies with diabetes, renal failure and hypertension presented unresponsive with severe acidosis, lactataemia, bradycardia and hypotension. After the initial survey, hypotension and bradycardia were noted before she went into cardiac arrest. After resuscitation and intubation, she was moved to the intensive care unit for dialysis and supportive care. After seven hours of dialysis, her hypote...
Source: Tidsskrift for den Norske Laegeforening - February 22, 2023 Category: General Medicine Authors: Olav Langedrag Fj ære Christer Arthurson Kjetil Gorseth Ringdal P ål Christian Wold Morberg Source Type: research