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Condition: Arthritis
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Total 2071 results found since Jan 2013.
Distinctive Expression of Bone Metabolism-related Genes between PBMCs from Condylar Hyperplasia, Rheumatoid Arthritis, and Ankylosing Spondylitis Patients
Iran J Allergy Asthma Immunol. 2020 Oct 18;19(5):539-544. doi: 10.18502/ijaai.v19i5.4471.ABSTRACTBone morphogenetic proteins (BMPs) and wingless (Wnt) signaling molecules and their antagonists, such as sclerostin and noggin, have been identified to have different effects on bone metabolism. This research intended to evaluate the transcript levels of CTNNB1 (catenin beta 1protein), SOST (sclerostin protein), BMP4 (Bone Morphogenetic Protein 4 protein), and NOG (noggin protein) bone metabolism-related genes in peripheral blood mononuclear cells (PBMCs) from condylar hyperplasia (CH) patients in comparison to rheumatoid arthr...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 19, 2021 Category: Allergy & Immunology Authors: Reza Amirzargar Gholamreza Shirani Shokoufeh Raisian Maryam Davoudi Saeed Aslani Shiva Poursani Shaghayegh Khanmohammadi Mahdi Mahmoudi Mohammad Bayat Source Type: research
MicroRNAs as the Important Regulators of T Helper 17 Cells: A Narrative Review
Iran J Allergy Asthma Immunol. 2020 Dec 19;19(6):589-601. doi: 10.18502/ijaai.v19i6.4928.ABSTRACTT helper (Th)-17 cells are a distinct and important subset of Th cells and their functions are due to the ability of production and secretion of key cytokines in the immune system such as interleukin (IL)-17, IL-22, IL-21, and tumor necrosis factor-α (TNF-α). According to these cytokines, these cells have vital roles in the pathogenesis of the disease such as rheumatoid arthritis (RA) and osteoarthritis (OA). Nowadays, microRNAs (miRNAs) are defined as essential regulators of cell function by targeting transcription factors a...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 19, 2021 Category: Allergy & Immunology Authors: Mahdi Atabaki Zhaleh Shariati-Sarabi Mehdi Barati Jalil Tavakkol-Afshari Mojgan Mohammadi Source Type: research
Distinctive Expression of Bone Metabolism-related Genes between PBMCs from Condylar Hyperplasia, Rheumatoid Arthritis, and Ankylosing Spondylitis Patients
Iran J Allergy Asthma Immunol. 2020 Oct 18;19(5):539-544. doi: 10.18502/ijaai.v19i5.4471.ABSTRACTBone morphogenetic proteins (BMPs) and wingless (Wnt) signaling molecules and their antagonists, such as sclerostin and noggin, have been identified to have different effects on bone metabolism. This research intended to evaluate the transcript levels of CTNNB1 (catenin beta 1protein), SOST (sclerostin protein), BMP4 (Bone Morphogenetic Protein 4 protein), and NOG (noggin protein) bone metabolism-related genes in peripheral blood mononuclear cells (PBMCs) from condylar hyperplasia (CH) patients in comparison to rheumatoid arthr...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 19, 2021 Category: Allergy & Immunology Authors: Reza Amirzargar Gholamreza Shirani Shokoufeh Raisian Maryam Davoudi Saeed Aslani Shiva Poursani Shaghayegh Khanmohammadi Mahdi Mahmoudi Mohammad Bayat Source Type: research
Association of rs3135500 and rs3135499 Polymorphisms in the MicroRNA-binding Site of Nucleotide-binding Oligomerization Domain 2 (NOD2) Gene with Susceptibility to Rheumatoid Arthritis
Iran J Allergy Asthma Immunol. 2021 Apr 17;20(2):178-187.ABSTRACTThe nucleotide-binding oligomerization domain 2 (NOD2) is the key regulator of inflammatory responses and has been involved in the pathogenesis of rheumatoid arthritis (RA). Laboratory and in silico evaluations have demonstrated that some polymorphisms in 3'UTR of NOD2 gene could influence the secondary structure of this region and similarly thermodynamic features of hybridization site and finally deregulate the expression of NOD2. In the current study, for the first time, we evaluated the possible association between single nucleotide polymorphisms (SNPs) rs...
Source: Iranian Journal of Allergy, Asthma and Immunology - April 27, 2021 Category: Allergy & Immunology Authors: Naeim Ehtesham Behrang Alani Deniz Mortazavi Sara Azhdari Taiebe Kenarangi Emran Esmaeilzadeh Bahram Pakzad Source Type: research
