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Hydrogen sulfide in physiological and pathological mechanisms in brain.
Abstract Hydrogen sulfide (H2S) has been widely known as a toxic gas for more than 300 years in scientific community. However, the understanding about this small molecule has changed recently as many physiological and pathological roles of H2S have been identified. Presently, H2S is considered as a third gasotransmitter and neuromodulator after carbon monoxide (CO) and nitric oxide (NO). H2S plays an important role in memory and cognition through mechanisms that involve long-term potentiation (LTP) and calcium homeostasis in the neuronal cells. The disturbances in endogenous H2S levels and trans-sulfuration pathwa...
Source: CNS and Neurological Disorders Drug Targets - June 4, 2018 Category: Drugs & Pharmacology Authors: Kumar M, Sandhir R Tags: CNS Neurol Disord Drug Targets Source Type: research

A New Study Shows How Seriously Air Pollution Can Affect Your Heartbeat
For China’s 1.4 billion people, the simple act of breathing has long been something of a risk. Living in the ninth-dirtiest country in the world in terms of air quality, China’s residents lose an average of 2.6 years of life per capita due to atmospheric pollution alone. The greatest risk, of course, is pulmonary, with air pollution leading to shortness of breath, wheezing, coughing, asthma episodes, and chest pain. But pollution affects the heart too; the U.S. Environmental Protection Agency reports that exposure to fine-particulate matter as well as to nitrogen oxides alone can lead to premature aging in bloo...
Source: TIME: Health - May 1, 2023 Category: Consumer Health News Authors: Jeffrey Kluger Tags: Uncategorized climate change Climate Is Everything Environment healthscienceclimate Source Type: news