• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Bio-Distribution of Infused Human Umbilical Cord Blood Cells in Alzheimer's Disease-Like Murine Model.
In this report, we followed the bioavailability of HUCBCs in AD-like transgenic PSAPP mice and non-transgenic Sprague-Dawley rats. HUCBCs were injected in tail veins of mice or rats at a single dose of 1 x 10(6) or 2.2 x 10(6) cells, respectively, prior to harvesting of tissues at 24 hours, 7 days, and 30 days after injection. For determination of HUCBC distribution, tissues from both species were subjected to total DNA isolation and PCR amplification of the gene for human glycerol-3-phosphate dehydrogenase. Our results show a relatively similar bio-distribution and retention of HUCBCs in both mouse and rat organs. HUCBCs ...
Source: Cell Transplantation - September 25, 2015 Category: Cytology Tags: Cell Transplant Source Type: research

Adipose Tissue Derived Stem Cells in Neural Regenerative Medicine.
In this study, several human clinical trials using ADSCs for neuronal disorders were investigated. It is suggested that ADSCs are one of the choices among various stem cells for translating into clinical application in the near future. PMID: 25647067 [PubMed - as supplied by publisher]
Source: Cell Transplantation - February 2, 2015 Category: Cytology Authors: Yeh DC, Chan TM, Harn HJ, Chiou TW, Chen HS, Lin ZS, Lin SZ Tags: Cell Transplant Source Type: research

Direct reprogrammed neuronal cells as a novel resource for cell transplantation therapy.
Abstract Cell transplantation/ replacement therapy is attractive as a novel strategy for neurological diseases such as Parkinson?s disease, Alzheimer?s disease, and stroke. To realize this therapy, safer and more therapeutic effective cell resources are now required. Since induced pluripotent stem (iPS) cells can retain high replication competence and pluripotency when they differentiate into various kinds of cells, they are regarded as a promising cell source for cell transplantation therapy. However, high tumorigenesis of iPS has to be overcome for clinical applications. Recent progress includes the combination ...
Source: Cell Transplantation - March 11, 2014 Category: Cytology Authors: Yamashita T, Abe K Tags: Cell Transplant Source Type: research