• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Cognitive deficits of pure subcortical vascular dementia vs Alzheimer disease: PiB-PET-based study
Conclusions: Patients with PiB(–) SVaD were better at memory but worse at frontal function than patients with PiB(+) AD. The differences in memory/frontal functions observed between the 2 groups, however, could not differentiate all individual data due to some overlap in the cutoff threshold.
Source: Neurology - February 4, 2013 Category: Neurology Authors: Yoon, C. W., Shin, J. S., Kim, H. J., Cho, H., Noh, Y., Kim, G. H., Chin, J. H., Oh, S. J., Kim, J. S., Choe, Y. S., Lee, K.-H., Lee, J.-H., Seo, S. W., Na, D. L. Tags: All Cognitive Disorders/Dementia, Vascular dementia, Cognitive neuropsychology in dementia, Assessment of cognitive disorders/dementia ARTICLE Source Type: research

Prognostic Risk Profiles for Dementia: A Machine Learning Approach (P1.091)
Conclusions: These results suggest that vascular factors may play a greater role in dementia pathogenesis than currently thought. Furthermore, using this method we were able to achieve prediction accuracies that compare favorably with the existing literature.Disclosure: Dr. Morgenstern has nothing to disclose. Dr. Daley has nothing to disclose. Dr. Hachinski has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Morgenstern, J., Daley, M., Hachinski, V. Tags: Epidemiology of Aging and Dementias Source Type: research

CSF biomarkers suggest a strong role of glial inflammation in the pathogenesis of frontotemporal dementia (P6.104)
Conclusions:FTD features increased YKL-40, sTREM2 and NfL, a profile that distinguishes it from controls and AD. The dynamic relationship between CSF neuroinflammatory and injury biomarkers and disease severity support a strong role for neuroinflammation in the progression of FTD.Study Supported by:NIH 2T32 AG023481, National Institutes of Health, 4-Repeat Tauopathy Neuroimaging Initiative (4RTNI, AG03879); the National Center for Advancing Translational Science (NCATS) and National Institute of Neurological Disorders and Stroke (NINDS), Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL, NS09208...
Source: Neurology - April 17, 2017 Category: Neurology Authors: -Martinez, J. R., Calvet, M. S., Karydas, A., Kleinberger, G., Kramer, J., Rosen, H., Rabinovici, G., Miller, B., Fagan, A., Haass, C., Boxer, A. Tags: Aging and Dementia Poster Discussion Session: Novel Approaches in Neurodegenerative Diseases: Genetics, Biomarkers, and Therapies Source Type: research