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IJERPH, Vol. 19, Pages 15486: Intermittent Use of Anti-Hormonal Agents for the Endocrine Therapy of Sex-Hormone-Dependent Breast and Prostate Cancer: A Protocol for a Systematic Review
üs Therapies with the continuous administration of anti-hormonal agents in sex-hormone-dependent malignancies such as prostate and breast carcinomas often lead to the development of resistant tumor cells. A systematic evaluation of the use and effects of the intermittent application of endocrine therapy could provide information on the state of knowledge in this research area. PubMed, Cochrane Library, Embase, and Web of Science will be systematically searched using pretested search strategies. Randomized and non-randomized controlled trials, pragmatic trials, case–control, and comparative cohort studies...
Source: International Journal of Environmental Research and Public Health - November 22, 2022 Category: Environmental Health Authors: Keszty üs K ämpfer Keszty üs Tags: Protocol Source Type: research

IJERPH, Vol. 18, Pages 8500: Impact of Sexual Activity on the Risk of Male Genital Tumors: A Systematic Review of the Literature
Calace Manfredi Most cancers are related to lifestyle and environmental risk factors, including smoking, alcohol consumption, dietary habits, and environment (occupational exposures). A growing interest in the association between sexual activity (SA) and the development of different types of tumors in both men and women has been recorded in recent years. The aim of the present systematic review is to describe and critically discuss the current evidence regarding the association between SA and male genital cancers (prostatic, penile, and testicular), and to analyze the different theories and biological mechanisms...
Source: International Journal of Environmental Research and Public Health - August 11, 2021 Category: Environmental Health Authors: Crocetto Arcaniolo Napolitano Barone La Rocca Capece Caputo Imbimbo De Sio Calace Manfredi Tags: Review Source Type: research

IJERPH, Vol. 17, Pages 1345: Shift Work and Prostate Cancer: An Updated Systematic Review and Meta-Analysis
-Moleón The International Agency of Research in Cancer (IARC) has recently confirmed shift work as a type 2A carcinogen. The results presented in published epidemiological studies regarding prostate cancer are inconsistent and the association remains controversial. The aims of this study were: (a) to investigate the possible association between shift work and prostate cancer incidence, identifying possible sources of heterogeneity; and (b) to analyze the potential effect of publication bias. A search for cohort and case-control studies published from January 1980 to November 2019 was conducted. The quality of the art...
Source: International Journal of Environmental Research and Public Health - February 18, 2020 Category: Environmental Health Authors: Rivera-Izquierdo Mart ínez-Ruiz Castillo-Ruiz Manzaneda-Nav ío P érez-Gómez Jim énez-Moleón Tags: Review Source Type: research